Tag: Notch Signaling

Biology

Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling

Newsemia
by Jian Heng, Peng Lv, Yifan Zhang, Xinjie Cheng, Lu Wang, Dongyuan Ma, Feng Liu It is well known that various developmental signals play diverse...
Biology

Inhibition of Notch signaling rescues cardiovascular development in Kabuki Syndrome

Newsemia
by Maria de los Angeles Serrano, Bradley L. Demarest, Tarlynn Tone-Pah-Hote, Martin Tristani-Firouzi, H. Joseph Yost Kabuki Syndrome patients have a spectrum of congenital disorders,...
Biology

Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ<sup>+</sup>CD8αα<sup>+</sup> T cells

Newsemia
by Chieko Ishifune, Shin-ichi Tsukumo, Yoichi Maekawa, Katsuto Hozumi, Doo Hyun Chung, Chihiro Motozono, Sho Yamasaki, Hiroyasu Nakano, Koji Yasutomo Intestinal intraepithelial lymphocytes (IELs) expressing...
Biology

A Notch-mediated, temporal asymmetry in BMP pathway activation promotes photoreceptor subtype diversification

Newsemia
by Elise Cau, Brice Ronsin, Laurianne Bessière, Patrick Blader Neural progenitors produce neurons whose identities can vary as a function of the time that specification...
Biology

Lens differentiation is controlled by the balance between PDGF and FGF signaling

Newsemia
by Hongge Li, Yingyu Mao, Michael Bouaziz, Honglian Yu, Xiuxia Qu, Fen Wang, Gen-Sheng Feng, Carrie Shawber, Xin Zhang How multiple receptor tyrosine kinases coordinate...
Biology

Gene expression in response to optical defocus of opposite signs reveals bidirectional mechanism of visually guided eye growth

Newsemia
by Tatiana V. Tkatchenko, David Troilo, Alexandra Benavente-Perez, Andrei V. Tkatchenko Myopia (nearsightedness) is the most common eye disorder, which is rapidly becoming one of...
Biology

<i>Jagged1/Notch2</i> controls kidney fibrosis via <i>Tfam</i>-mediated metabolic reprogramming

Newsemia
by Shizheng Huang, Jihwan Park, Chengxiang Qiu, Kiwung Chung, Szu-yuan Li, Yasemin Sirin, Seung Hyeok Han, Verdon Taylor, Ursula Zimber-Strobl, Katalin Susztak While Notch signaling...
Latest News

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

Newsemia
For the first time, Mount Sinai researchers have identified a way to make large numbers of immune cells that can help prevent cancer reoccurrence, according...

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