Tag : Neuronal dendrites

Biology

Dendritic integration in olfactory bulb granule cells upon simultaneous multispine activation: Low thresholds for nonlocal spiking activity

Newsemia
by Max Mueller, Veronica Egger The inhibitory axonless olfactory bulb granule cells form reciprocal dendrodendritic synapses with mitral and tufted cells via large spines, mediating...
Biology

Spastin depletion increases tubulin polyglutamylation and impairs kinesin-mediated neuronal transport, leading to working and associative memory deficits

Newsemia
by André T. Lopes, Torben J. Hausrat, Frank F. Heisler, Kira V. Gromova, Franco L. Lombino, Timo Fischer, Laura Ruschkies, Petra Breiden, Edda Thies, Irm...
Biology

CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles

Newsemia
by Alessandro Moro, Geeske M. van Woerden, Ruud F. Toonen, Matthijs Verhage Ca2+/calmodulin-dependent kinase II (CaMKII) regulates synaptic plasticity in multiple ways, supposedly including the...
Biology

ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons

Newsemia
by Jelmer Willems, Arthur P. H. de Jong, Nicky Scheefhals, Eline Mertens, Lisa A. E. Catsburg, Rogier B. Poorthuis, Fred de Winter, Joost Verhaagen, Frank...
Biology

BigBrain 3D atlas of cortical layers: Cortical and laminar thickness gradients diverge in sensory and motor cortices

Newsemia
by Konrad Wagstyl, Stéphanie Larocque, Guillem Cucurull, Claude Lepage, Joseph Paul Cohen, Sebastian Bludau, Nicola Palomero-Gallagher, Lindsay B. Lewis, Thomas Funck, Hannah Spitzer, Timo Dickscheid,...
Biology

The receptor tyrosine kinase Ror is required for dendrite regeneration in <i>Drosophila</i> neurons

Newsemia
by Derek M. R. Nye, Richard M. Albertson, Alexis T. Weiner, J. Ian Hertzler, Matthew Shorey, Deborah C. I. Goberdhan, Clive Wilson, Kevin A. Janes,...
Biology

Endosomal Wnt signaling proteins control microtubule nucleation in dendrites

Newsemia
by Alexis T. Weiner, Dylan Y. Seebold, Pedro Torres-Gutierrez, Christin Folker, Rachel D. Swope, Gregory O. Kothe, Jessica G. Stoltz, Madeleine K. Zalenski, Christopher Kozlowski,...
Biology

Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction

Newsemia
by Ashley L. Comer, Tushare Jinadasa, Balaji Sriram, Rhushikesh A. Phadke, Lisa N. Kretsge, Thanh P. H. Nguyen, Giovanna Antognetti, James P. Gilbert, Jungjoon Lee,...
Biology

SorCS1-mediated sorting in dendrites maintains neurexin axonal surface polarization required for synaptic function

Newsemia
by Luís F. Ribeiro, Ben Verpoort, Julie Nys, Kristel M. Vennekens, Keimpe D. Wierda, Joris de Wit The pre- and postsynaptic membranes comprising the synaptic...
Biology

Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons

Newsemia
by Naila Haq, Christoph Schmidt-Hieber, Fernando J. Sialana, Lorenza Ciani, Janosch P. Heller, Michelle Stewart, Liz Bentley, Sara Wells, Richard J. Rodenburg, Patrick M. Nolan,...
Biology

Differential role of pre- and postsynaptic neurons in the activity-dependent control of synaptic strengths across dendrites

Newsemia
by Mathieu Letellier, Florian Levet, Olivier Thoumine, Yukiko Goda Neurons receive a large number of active synaptic inputs from their many presynaptic partners across their...
Biology

Fast calcium transients in dendritic spines driven by extreme statistics

Newsemia
by Kanishka Basnayake, David Mazaud, Alexis Bemelmans, Nathalie Rouach, Eduard Korkotian, David Holcman Fast calcium transients (<10 ms) remain difficult to analyse in cellular microdomains,...
Biology

Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice

Newsemia
by Katarzyna O. Rojek, Joanna Krzemień, Hubert Doleżyczek, Paweł M. Boguszewski, Leszek Kaczmarek, Witold Konopka, Marcin Rylski, Jacek Jaworski, Lars Holmgren, Tomasz J. Prószyński The...
Biology

Serotonin receptor HTR6-mediated mTORC1 signaling regulates dietary restriction–induced memory enhancement

Newsemia
by Ling-Ling Teng, Guan-Ling Lu, Lih-Chu Chiou, Wei-Sheng Lin, Ya-Yun Cheng, Tai-En Hsueh, Yi-Ching Huang, Nai-Hsuan Hwang, Jin-Wei Yeh, Ruey-Ming Liao, Shou-Zen Fan, Jui-Hung Yen,...
Biology

Vocal practice regulates singing activity–dependent genes underlying age-independent vocal learning in songbirds

Newsemia
by Shin Hayase, Hongdi Wang, Eri Ohgushi, Masahiko Kobayashi, Chihiro Mori, Haruhito Horita, Katsuhiko Mineta, Wan-chun Liu, Kazuhiro Wada The development of highly complex vocal...
Biology

Axonal sodium channel Na<sub>V</sub>1.2 drives granule cell dendritic GABA release and rapid odor discrimination

Newsemia
by Daniel Nunes, Thomas Kuner Dendrodendritic synaptic interactions between olfactory bulb mitral and granule cells represent a key neuronal mechanism of odor discrimination. Dendritic release...

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