Tag : myeloid

Pharma / Biotech

Anti-FLT3 nanoparticles for acute myeloid leukemia: Preclinical pharmacology and pharmacokinetics.

Newsemia
Anti-FLT3 nanoparticles for acute myeloid leukemia: Preclinical pharmacology and pharmacokinetics. J Control Release. 2020 May 16;: Authors: Park M, Vaikari VP, Lam AT, Zhang Y,...
Pediatrics

Cardioprotective Drug Prevents Severe Cardiac Events in Children Undergoing Chemotherapy for Acute Myeloid Leukemia

Newsemia
The cardioprotective drug dexrazoxane preserved cardiac function in pediatric patients undergoing chemotherapy for acute myeloid leukemia (AML) without compromising overall patient survival and potentially improving...
Pharma / Biotech

Food-effect study of nilotinib in chronic myeloid leukaemia (NiFo study): enabling dose reduction and relief of treatment burden.

Newsemia
Related Articles Food-effect study of nilotinib in chronic myeloid leukaemia (NiFo study): enabling dose reduction and relief of treatment burden. Eur J Haematol. 2020 Apr...
Latest News

PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells

Newsemia
Foxall, E; Staszowska, A; Hirvonen, LM; Georgouli, M; Ciccioli, M; Rimmer, A; Williams, L; … Wells, CM; + view all Foxall, E; Staszowska, A; Hirvonen,...
Pharma / Biotech

Pharmacology of tyrosine kinase inhibitors in chronic myeloid leukemia; a clinician's perspective.

Newsemia
Related Articles Pharmacology of tyrosine kinase inhibitors in chronic myeloid leukemia; a clinician’s perspective. Daru. 2020 Jan 03;: Authors: Pushpam D, Bakhshi S Abstract OBJECTIVE:...
Pediatrics

ASH: Research revises classification of acute myeloid leukemia and myelodysplastic syndrome

Newsemia
Results from a study conducted by St. Jude Children’s Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the...
Dentistry

Serum Flt3 ligand is a biomarker of progenitor cell mass and prognosis in acute myeloid leukemia.

Newsemia
Serum Flt3 ligand is a biomarker of progenitor cell mass and prognosis in acute myeloid leukemia. Blood Adv. 2019 Oct 22;3(20):3052-3061 Authors: Milne P, Wilhelm-Benartzi...
Biology

PIKfyve Deficiency in Myeloid Cells Impairs Lysosomal Homeostasis in Macrophages and Promotes Systemic Inflammation in Mice [Research Article]

Newsemia
Macrophages are professional phagocytes that are essential for host defense and tissue homeostasis. Proper membrane trafficking and degradative functions of the endolysosomal system are known...
Latest News

Celgene Announces Phase 3 QUAZAR® AML-001 Study of CC-486 as Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia Met Primary and Key Secondary Endpoints

Newsemia
SUMMIT, N.J.–(BUSINESS WIRE)–Celgene Corporation (NASDAQ: CELG) today announced top-line results from the international phase 3, randomized, double-blind, placebo-controlled study, QUAZAR AML-001. The study evaluated the...
Latest News

Comparative analysis of melphalan versus busulphan T-cell deplete conditioning using alemtuzumab in unrelated donor stem cell transplantation for acute myeloid leukaemia

Newsemia
Sellar, RS; Mehra, V; Fox, TA; Grigg, A; Kulasekararaj, A; Sarma, A; de Lavallade, H; … Potter, VT; + view all Sellar, RS; Mehra, V;...
Latest News

Vor Biopharma Completes $42 Million Series A Financing Round to Advance Lead Cell Therapy Product Candidate for the Treatment of Acute Myeloid Leukemia

Newsemia
BOSTON–(BUSINESS WIRE)–Vor Biopharma, an immuno-oncology company, today announced a $42 million Series A financing round led by 5AM Ventures and RA Capital Management. Source link...

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