Tag: Mutagenesis

Biology

Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity

Newsemia
by Tony Ngo, Bryan S. Stephens, Martin Gustavsson, Lauren G. Holden, Ruben Abagyan, Tracy M. Handel, Irina Kufareva Chemokines and their receptors are orchestrators of...
Biology

Efficient Degradation of Poly(ethylene terephthalate) with Thermobifida fusca Cutinase Exhibiting Improved Catalytic Activity Generated using Mutagenesis and Additive-based Approaches

Newsemia
Efficient Degradation of Poly(ethylene terephthalate) with Thermobifida fusca Cutinase Exhibiting Improved Catalytic Activity Generated using Mutagenesis and Additive-based Approaches Source link...
Biology

Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins

Newsemia
by Rossana Colón-Thillet, Emily Hsieh, Laura Graf, Richard N. McLaughlin Jr, Janet M. Young, Georg Kochs, Michael Emerman, Harmit S. Malik Antagonistic interactions drive host–virus...
Biology

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

Newsemia
by Cynthia J. Sakofsky, Natalie Saini, Leszek J. Klimczak, Kin Chan, Ewa P. Malc, Piotr A. Mieczkowski, Adam B. Burkholder, David Fargo, Dmitry A. Gordenin...
Biology

Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature

Newsemia
by Natalya P. Degtyareva, Natalie Saini, Joan F. Sterling, Victoria C. Placentra, Leszek J. Klimczak, Dmitry A. Gordenin, Paul W. Doetsch Redox stress is a...
Biology

Creation of haemoglobin A1c direct oxidase from fructosyl peptide oxidase by combined structure-based site specific mutagenesis and random mutagenesis

Newsemia
The post Creation of haemoglobin A1c direct oxidase from fructosyl peptide oxidase by combined structure-based site specific mutagenesis and random mutagenesis appeared first on Biochemistry...
Biology

Heterochromatin delays CRISPR-Cas9 mutagenesis but does not influence the outcome of mutagenic DNA repair

Newsemia
by Eirini M. Kallimasioti-Pazi, Keerthi Thelakkad Chathoth, Gillian C. Taylor, Alison Meynert, Tracy Ballinger, Martijn J. E. Kelder, Sébastien Lalevée, Ildem Sanli, Robert Feil, Andrew...
AI/ML

Gene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicans.

Newsemia
Related Articles Gene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicans. MBio. 2018 Oct 30;9(5):...
Pharma / Biotech

ALBUTEROL (Albuterol Sulfate) Tablet [Mylan Pharmaceuticals Inc.]

Newsemia
Updated Date: Sep 26, 2018 EST...
Pharma / Biotech

DENAVIR (Penciclovir) Cream [Prestium Pharma, Inc.]

Newsemia
Updated Date: Sep 25, 2018 EST...
Pharma / Biotech

OVIDE (Malathion) Lotion [Taro Pharmaceuticals U.S.A., Inc.]

Newsemia
Updated Date: Jul 20, 2018 EST...

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