Tag : Mtorc1

Biology

The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

Newsemia
The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and...
Biology

Partial Inhibition of mTORC1 in Aged Rats Counteracts the Decline in Muscle Mass and Reverses Molecular Signaling Associated with Sarcopenia [Research Article]

Newsemia
There is a lack of pharmacological interventions available for sarcopenia, a progressive age-associated loss of muscle mass, leading to a decline in mobility and quality...
Latest News

mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β1-induced collagen biosynthesis

Newsemia
Selvarajah, B; Azuelos, I; Platé, M; Guillotin, D; Forty, EJ; Contento, G; Woodcock, HV; … Chambers, RC; + view all Selvarajah, B; Azuelos, I; Platé,...
Neurology

Chronic mTORC1 inhibition rescues behavioral and biochemical deficits resulting from neuronal Depdc5 loss in mice.

Newsemia
Related Articles Chronic mTORC1 inhibition rescues behavioral and biochemical deficits resulting from neuronal Depdc5 loss in mice. Hum Mol Genet. 2019 Jun 07;: Authors: Yuskaitis...
Biology

Serotonin receptor HTR6-mediated mTORC1 signaling regulates dietary restriction–induced memory enhancement

Newsemia
by Ling-Ling Teng, Guan-Ling Lu, Lih-Chu Chiou, Wei-Sheng Lin, Ya-Yun Cheng, Tai-En Hsueh, Yi-Ching Huang, Nai-Hsuan Hwang, Jin-Wei Yeh, Ruey-Ming Liao, Shou-Zen Fan, Jui-Hung Yen,...
Pediatrics

Scientists Identify a Protein Complex That Shapes the Destiny of T Cells

Newsemia
St. Jude Children’s Research Hospital scientists report the protein complex mTORC1 serves as a bridge between environmental signals and metabolic programs to influence the fate...

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