Tag : mouse

Neurology

Lanthionine ketimine ester improves outcome in an MPTP-induced mouse model of Parkinson's disease via suppressions of CRMP2 phosphorylation and microglial activation

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Parkinson’s disease (PD) is characterized by progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc). Levodopa (L-Dopa), the current main treatment for...
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Administering specialized lipids prevents memory loss, inflammation in Down syndrome mouse model

Newsemia
Individuals with Down syndrome are at a much greater risk of developing Alzheimer’s disease, with inflammation of the brain starting early in life and the...
AI/ML

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing.

Newsemia
Related Articles The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing. PLoS Pathog. 2020 Mar 12;16(3):e1008391...
AI/ML

Machine learning analysis of whole mouse brain vasculature.

Newsemia
Related Articles Machine learning analysis of whole mouse brain vasculature. Nat Methods. 2020 Mar 11;: Authors: Todorov MI, Paetzold JC, Schoppe O, Tetteh G, Shit...
Gastroenterology

Fructo-oligosaccharides ameliorate steatohepatitis, visceral adiposity, and associated chronic inflammation via increased production of short-chain fatty acids in a mouse model of non-alcoholic steatohepatitis

Newsemia
Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. Within the spectrum of NAFLD, non-alcoholic steatohepatitis (NASH) in combination with hepatic inflammation...
Gastroenterology

P150 ENHANCING EPITHELIAL BARRIER FUNCTION WITH NOVEL E-CADHERIN ACTIVATING MONOCLONAL ANTIBODIES REDUCES INFLAMMATORY BOWEL DISEASE PROGRESSION IN MOUSE MODELS

Newsemia
Deficits in gastrointestinal (GI) epithelial barrier function play important roles in the pathogenesis of Inflammatory Bowel Disease (IBD). The CDH1 gene encoding E-cadherin, a key...
Dentistry

Critical role of PD-L1 expression on non-tumor cells rather than on tumor cells for effective anti-PD-L1 immunotherapy in a transplantable mouse hematopoietic tumor model.

Newsemia
Related Articles Critical role of PD-L1 expression on non-tumor cells rather than on tumor cells for effective anti-PD-L1 immunotherapy in a transplantable mouse hematopoietic tumor...
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Prophylactic dendritic cell vaccination controls pancreatic cancer growth in a mouse model

Newsemia
Shangguan, A; Shang, N; Figini, M; Pan, L; Yang, J; Ma, Q; Hu, S; … Zhang, Z; + view all Shangguan, A; Shang, N; Figini,...

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