Tag: mitotic

Biology

Nocodazole-Induced Expression and Phosphorylation of Anillin and Other Mitotic Proteins Are Decreased in DNA-Dependent Protein Kinase Catalytic Subunit-Deficient Cells and Rescued by Inhibition of the Anaphase-Promoting Complex/Cyclosome with proTAME but Not Apcin [Research Article]

Newsemia
The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) has well-established roles in DNA double-strand break repair, and recently, nonrepair functions have also been reported. To better...
Biology

Mitotic phosphorylation of the ULK complex regulates cell cycle progression

Newsemia
by Akinori Yamasaki, Yui Jin, Yoshinori Ohsumi Autophagy is an intracellular degradation pathway targeting organelles and macromolecules, thereby regulating various cellular functions. Phosphorylation is a...
Biology

ULK1-ATG13 and their mitotic phospho-regulation by CDK1 connect autophagy to cell cycle

Newsemia
by Zhiyuan Li, Xiaofei Tian, Xinmiao Ji, Junjun Wang, Hanxiao Chen, Dongmei Wang, Xin Zhang Unc-51-like autophagy activating kinase 1 (ULK1)–autophagy-related 13 (ATG13) is the...
Biology

YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators

Newsemia
by Qili Fei, Zhongyu Zou, Ian A. Roundtree, Hui-Lung Sun, Chuan He The N6-methyladenosine (m6A) modification regulates mRNA stability and translation. Here, we show that...
Biology

Loss of MYO5B expression deregulates late endosome size which hinders mitotic spindle orientation

Newsemia
by Changsen Leng, Arend W. Overeem, Fernando Cartón-Garcia, Qinghong Li, Karin Klappe, Jeroen Kuipers, Yingying Cui, Inge S. Zuhorn, Diego Arango, Sven C. D. van...
Latest News

Phosphoproteome dynamics during mitotic exit in budding yeast

Newsemia
Touati, SA; Kataria, M; Jones, AW; Snijders, AP; Uhlmann, F; (2018) Phosphoproteome dynamics during mitotic exit in budding yeast. EMBO Journal , 37 (10) ,...
Latest News

Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression

Newsemia
Adib, R; Montgomery, JM; Atherton, J; O’Regan, L; Richards, MW; Straatman, KR; Roth, D; … Fry, AM; + view all Adib, R; Montgomery, JM; Atherton,...
Biology

Rapid antigen diversification through mitotic recombination in the human malaria parasite <i>Plasmodium falciparum</i>

Newsemia
by Xu Zhang, Noah Alexander, Irina Leonardi, Christopher Mason, Laura A. Kirkman, Kirk W. Deitsch Malaria parasites possess the remarkable ability to maintain chronic infections...
Pharma / Biotech

A class of novel tubulin polymerization inhibitors exert effective anti-tumor activity via mitotic catastrophe.

Newsemia
Related Articles A class of novel tubulin polymerization inhibitors exert effective anti-tumor activity via mitotic catastrophe. Eur J Med Chem. 2018 Dec 17;163:896-910 Authors: Zhang...

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