Tag : mitosis

Biology

Interphase-arrested <i>Drosophila</i> embryos activate zygotic gene expression and initiate mid-blastula transition events at a low nuclear-cytoplasmic ratio

Newsemia
by Isaac J. T. Strong, Xiaoyun Lei, Fang Chen, Kai Yuan, Patrick H. O’Farrell Externally deposited eggs begin development with an immense cytoplasm and a...
Biology

Dynamic centriolar localization of Polo and Centrobin in early mitosis primes centrosome asymmetry

Newsemia
by Emmanuel Gallaud, Anjana Ramdas Nair, Nicole Horsley, Arnaud Monnard, Priyanka Singh, Tri Thanh Pham, David Salvador Garcia, Alexia Ferrand, Clemens Cabernard Centrosomes, the main...
Biology

Acute inhibition of centriolar satellite function and positioning reveals their functions at the primary cilium

Newsemia
by Özge Z. Aydin, Sevket Onur Taflan, Can Gurkaslar, Elif Nur Firat-Karalar Centriolar satellites are dynamic, membraneless granules composed of over 200 proteins. They store,...
Biology

Mitotic phosphorylation of the ULK complex regulates cell cycle progression

Newsemia
by Akinori Yamasaki, Yui Jin, Yoshinori Ohsumi Autophagy is an intracellular degradation pathway targeting organelles and macromolecules, thereby regulating various cellular functions. Phosphorylation is a...
Biology

ULK1-ATG13 and their mitotic phospho-regulation by CDK1 connect autophagy to cell cycle

Newsemia
by Zhiyuan Li, Xiaofei Tian, Xinmiao Ji, Junjun Wang, Hanxiao Chen, Dongmei Wang, Xin Zhang Unc-51-like autophagy activating kinase 1 (ULK1)–autophagy-related 13 (ATG13) is the...
Latest News

Researchers discover physiological mechanisms underlying pediatric B-ALL

Newsemia
B-cell acute lymphoblastic leukemia (B-ALL) is characterized by the accumulation of abnormal immature B-cell precursors in the bone marrow and is the most common pediatric...
Biology

Evolutionary repair: Changes in multiple functional modules allow meiotic cohesin to support mitosis

Newsemia
by Yu-Ying Phoebe Hsieh, Vasso Makrantoni, Daniel Robertson, Adèle L. Marston, Andrew W. Murray The role of proteins often changes during evolution, but we do...
Biology

Image-based analysis of living mammalian cells using label-free 3D refractive index maps reveals new organelle dynamics and dry mass flux

Newsemia
by Patrick A. Sandoz, Christopher Tremblay, F. Gisou van der Goot, Mathieu Frechin Holo-tomographic microscopy (HTM) is a label-free microscopy method reporting the fine changes...
Biology

Spontaneously slow-cycling subpopulations of human cells originate from activation of stress-response pathways

Newsemia
by Mingwei Min, Sabrina L. Spencer Slow-cycling subpopulations exist in bacteria, yeast, and mammalian systems. In the case of cancer, slow-cycling subpopulations have been proposed...

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