Tag: mitochondrial

Cardiology

Inhibition of chymotrypsin-like activity of the proteasome by ixazomib prevents mitochondrial dysfunction during myocardial ischemia.

Newsemia
Related Articles Inhibition of chymotrypsin-like activity of the proteasome by ixazomib prevents mitochondrial dysfunction during myocardial ischemia. PLoS One. 2020;15(5):e0233591 Authors: Sánchez G, Chalmers S,...
Neurology

Primary hypoparathyroidism and multiple neuraxial involvement in mitochondrial disorder due to the variant m.15043G>A in MT-CYB

Newsemia
Mitochondrial disorders (MIDs) are a phenotypically and genotypically heterogeneous group of diseases characterized by multisystem involvement with defective mitochondrial metabolism, structure, or maintenance [1]. Phenotypic...
Neurology

Increased intra-mitochondrial lipofuscin aggregates with spherical dense body formation in mitochondrial myopathy

Newsemia
Lipofuscin aggregation may result from incomplete degradation of damaged mitochondria by autophagy-lysosome pathway, and intra-mitochondrial lipofuscin aggregation may exacerbate mitochondrial abnormalities in mitochondrial myopathy (MM)...

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