Tag : microtubules

Biology

Spastin depletion increases tubulin polyglutamylation and impairs kinesin-mediated neuronal transport, leading to working and associative memory deficits

Newsemia
by André T. Lopes, Torben J. Hausrat, Frank F. Heisler, Kira V. Gromova, Franco L. Lombino, Timo Fischer, Laura Ruschkies, Petra Breiden, Edda Thies, Irm...
Biology

Dynamic centriolar localization of Polo and Centrobin in early mitosis primes centrosome asymmetry

Newsemia
by Emmanuel Gallaud, Anjana Ramdas Nair, Nicole Horsley, Arnaud Monnard, Priyanka Singh, Tri Thanh Pham, David Salvador Garcia, Alexia Ferrand, Clemens Cabernard Centrosomes, the main...
Biology

Acute inhibition of centriolar satellite function and positioning reveals their functions at the primary cilium

Newsemia
by Özge Z. Aydin, Sevket Onur Taflan, Can Gurkaslar, Elif Nur Firat-Karalar Centriolar satellites are dynamic, membraneless granules composed of over 200 proteins. They store,...
Biology

The receptor tyrosine kinase Ror is required for dendrite regeneration in <i>Drosophila</i> neurons

Newsemia
by Derek M. R. Nye, Richard M. Albertson, Alexis T. Weiner, J. Ian Hertzler, Matthew Shorey, Deborah C. I. Goberdhan, Clive Wilson, Kevin A. Janes,...
Biology

Endosomal Wnt signaling proteins control microtubule nucleation in dendrites

Newsemia
by Alexis T. Weiner, Dylan Y. Seebold, Pedro Torres-Gutierrez, Christin Folker, Rachel D. Swope, Gregory O. Kothe, Jessica G. Stoltz, Madeleine K. Zalenski, Christopher Kozlowski,...
Biology

Tubulin mRNA stability is sensitive to change in microtubule dynamics caused by multiple physiological and toxic cues

Newsemia
by Ivana Gasic, Sarah A. Boswell, Timothy J. Mitchison The localization, mass, and dynamics of microtubules are important in many processes. Cells may actively monitor...
Biology

Morphology of mitochondria in spatially restricted axons revealed by cryo-electron tomography

Newsemia
by Tara D. Fischer, Pramod K. Dash, Jun Liu, M. Neal Waxham Neurons project axons to local and distal sites and can display heterogeneous morphologies...

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