Tag : Metabolites

Pharma / Biotech

Establishment of a simultaneous assay for lemborexant, a novel dual orexin receptor antagonist, and its three metabolites, and its application to a clinical protein binding study.

Newsemia
Related Articles Establishment of a simultaneous assay for lemborexant, a novel dual orexin receptor antagonist, and its three metabolites, and its application to a clinical...
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Blood test could help doctors identify patients at risk of developing type 2 diabetes

Newsemia
Scientists have identified metabolites in the blood that accurately predict whether a woman will develop type 2 diabetes after experiencing a transient form of illness...
Pharma / Biotech

Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression.

Newsemia
Related Articles Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression. Neuropsychopharmacology. 2020 Apr 06;: Authors: Farmer...
Pharma / Biotech

In vitro evaluation of reactive nature of E- and Z-guggulsterones and their metabolites in human liver microsomes using UHPLC-Orbitrap mass spectrometer.

Newsemia
Related Articles In vitro evaluation of reactive nature of E- and Z-guggulsterones and their metabolites in human liver microsomes using UHPLC-Orbitrap mass spectrometer. J Pharm...
Pharma / Biotech

Study on the Pharmacokinetics of Diazepam and Its Metabolites in Blood of Chinese People.

Newsemia
Related Articles Study on the Pharmacokinetics of Diazepam and Its Metabolites in Blood of Chinese People. Eur J Drug Metab Pharmacokinet. 2020 Mar 26;: Authors:...
Biology

Bacterially produced metabolites protect <i>C</i>. <i>elegans</i> neurons from degeneration

Newsemia
by Arles Urrutia, Víctor A. García-Angulo, Andrés Fuentes, Mauricio Caneo, Marcela Legüe, Sebastián Urquiza, Scarlett E. Delgado, Juan Ugalde, Paula Burdisso, Andrea Calixto Caenorhabditis elegans...
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Ulcerative colitis and a missing microbe in the gut

Newsemia
Ulcerative colitis is a seriously debilitating inflammatory disease of the bowel leading to crippling symptoms that can affect the quality of life severely. Researchers from...
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Wayne State researchers receive grant to develop new treatments for Barth syndrome

Newsemia
Barth syndrome is a rare and life-threatening, X-linked genetic disorder that primarily affects males and is passed from mother to son; women who are carriers...
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Scientists identify new biomarker for identifying individuals at risk of depression

Newsemia
Chronic pain, or inflammation, is believed to be one of the major factors in the onset of major depressive disorder. Source link...
Pharma / Biotech

Quantitative elucidation of maternal-to-fetal transfer of neonicotinoid pesticide clothianidin and its metabolites in mice.

Newsemia
Related Articles Quantitative elucidation of maternal-to-fetal transfer of neonicotinoid pesticide clothianidin and its metabolites in mice. Toxicol Lett. 2020 Jan 07;: Authors: Ohno S, Ikenaka...
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Beyond H&E Staining: How Spatial Molecular Analysis Is Driving Biomarker Discovery

Newsemia
An interview with Shannon Cornett Ph.D, discussing the use of MALDI-guided spatial molecular analysis for biomarker discovery. Source link...
Pharma / Biotech

Excretion of 4-fluoroamphetamine and three metabolites in urine after controlled oral ingestion.

Newsemia
Related Articles Excretion of 4-fluoroamphetamine and three metabolites in urine after controlled oral ingestion. J Pharm Biomed Anal. 2019 Nov 23;:113008 Authors: Toennes SW, Schneider...
Pharma / Biotech

Pharmacokinetics of Para-Aminosalicylic Acid and Its 2 Major Metabolites: A Potential Relationship to the Development of Gastrointestinal Intolerance.

Newsemia
Related Articles Pharmacokinetics of Para-Aminosalicylic Acid and Its 2 Major Metabolites: A Potential Relationship to the Development of Gastrointestinal Intolerance. J Clin Pharmacol. 2019 Nov...

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