Tag: Metabolites

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Circulating Plasma Metabolites and Cognitive Function in a Puerto Rican Cohort.

Newsemia
Related Articles Circulating Plasma Metabolites and Cognitive Function in a Puerto Rican Cohort. J Alzheimers Dis. 2020 Jul 20;: Authors: Palacios N, Lee JS, Scott...
Gastroenterology

Serum Levels of Metabolites Produced by Intestinal Microbes and Lipid Moieties Independently Associated With Acute on Chronic Liver Failure and Death in Patients With Cirrhosis

Newsemia
Hospitalized patients with cirrhosis often develop poor outcomes. We found that gut microbes and their circulating products collected on admission can predict death and acute-on-chronic...
Pharma / Biotech

Roles of diclofenac and its metabolites in immune activation associated with acute hepatotoxicity in TgCYP3A4/hPXR-humanized mice.

Newsemia
Related Articles Roles of diclofenac and its metabolites in immune activation associated with acute hepatotoxicity in TgCYP3A4/hPXR-humanized mice. Int Immunopharmacol. 2020 Jun 29;86:106723 Authors: Jiang...
Pharma / Biotech

Development and validation of a LC-MS/MS method for simultaneous determination of TQ-A3326 and its major metabolites in human plasma, urine and feces: application to pharmacokinetic assay.

Newsemia
Related Articles Development and validation of a LC-MS/MS method for simultaneous determination of TQ-A3326 and its major metabolites in human plasma, urine and feces: application...
Pharma / Biotech

Establishment of a simultaneous assay for lemborexant, a novel dual orexin receptor antagonist, and its three metabolites, and its application to a clinical protein binding study.

Newsemia
Related Articles Establishment of a simultaneous assay for lemborexant, a novel dual orexin receptor antagonist, and its three metabolites, and its application to a clinical...
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Blood test could help doctors identify patients at risk of developing type 2 diabetes

Newsemia
Scientists have identified metabolites in the blood that accurately predict whether a woman will develop type 2 diabetes after experiencing a transient form of illness...
Pharma / Biotech

Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression.

Newsemia
Related Articles Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression. Neuropsychopharmacology. 2020 Apr 06;: Authors: Farmer...
Pharma / Biotech

In vitro evaluation of reactive nature of E- and Z-guggulsterones and their metabolites in human liver microsomes using UHPLC-Orbitrap mass spectrometer.

Newsemia
Related Articles In vitro evaluation of reactive nature of E- and Z-guggulsterones and their metabolites in human liver microsomes using UHPLC-Orbitrap mass spectrometer. J Pharm...
Pharma / Biotech

Study on the Pharmacokinetics of Diazepam and Its Metabolites in Blood of Chinese People.

Newsemia
Related Articles Study on the Pharmacokinetics of Diazepam and Its Metabolites in Blood of Chinese People. Eur J Drug Metab Pharmacokinet. 2020 Mar 26;: Authors:...
Biology

Bacterially produced metabolites protect <i>C</i>. <i>elegans</i> neurons from degeneration

Newsemia
by Arles Urrutia, Víctor A. García-Angulo, Andrés Fuentes, Mauricio Caneo, Marcela Legüe, Sebastián Urquiza, Scarlett E. Delgado, Juan Ugalde, Paula Burdisso, Andrea Calixto Caenorhabditis elegans...
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Ulcerative colitis and a missing microbe in the gut

Newsemia
Ulcerative colitis is a seriously debilitating inflammatory disease of the bowel leading to crippling symptoms that can affect the quality of life severely. Researchers from...

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