Tag : metabolite

Latest News

Scientists investigate active plasma metabolite of remdesivir in SARS-CoV-2 mouse model

Newsemia
Using mouse models, scientists have investigated the active plasma metabolite of remdesivir, GS-441 524, and hydroxychloroquine as possible drug candidates in COVID-19. The research shows...
Cardiology

Heart Failure Disturbs Gut-Blood Barrier and Increases Plasma Trimethylamine, a Toxic Bacterial Metabolite.

Newsemia
Related Articles Heart Failure Disturbs Gut-Blood Barrier and Increases Plasma Trimethylamine, a Toxic Bacterial Metabolite. Int J Mol Sci. 2020 Aug 26;21(17): Authors: Drapala A,...
Neurology

Third Trimester Cerebellar Metabolite Concentrations are Decreased in Very Premature Infants with Structural Brain Injury.

Newsemia
Related Articles Third Trimester Cerebellar Metabolite Concentrations are Decreased in Very Premature Infants with Structural Brain Injury. Sci Rep. 2019 02 04;9(1):1212 Authors: Basu SK,...
Cardiology

A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors.

Newsemia
Related Articles A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors. Cell. 2020 03 05;180(5):862-877.e22 Authors: Nemet I, Saha PP, Gupta N, Zhu W,...
Neurology

Experimental therapy slows zika replication and prevents microcephaly in mice

Newsemia
An international group of researchers have discovered that inhibiting AHR (aryl hydrocarbon receptor), a protein with roles in regulating immunity, stem cell maintenance and cellular...
Pharma / Biotech

Systemic exposure to 5-Fluorouracil and its metabolite, 5,6-dihydrofluorouracil, and development of a limited sampling strategy for therapeutic drug management of 5-Fluorouracil in patients with gastrointestinal malignancy.

Newsemia
Related Articles Systemic exposure to 5-Fluorouracil and its metabolite, 5,6-dihydrofluorouracil, and development of a limited sampling strategy for therapeutic drug management of 5-Fluorouracil in patients...
Pharma / Biotech

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence.

Newsemia
Related Articles Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence. J Chromatogr...
Pharma / Biotech

Metabolite Identification Using An Ion Mobility-Enhanced Data-Independent Acquisition Strategy and Automated Data Processing.

Newsemia
Related Articles Metabolite Identification Using An Ion Mobility-Enhanced Data-Independent Acquisition Strategy and Automated Data Processing. Rapid Commun Mass Spectrom. 2020 Mar 24;:e8792 Authors: Radchenko T,...
AI/ML

Deep learning-based target metabolite isolation and big data-driven measurement uncertainty estimation in proton magnetic resonance spectroscopy of the brain.

Newsemia
Related Articles Deep learning-based target metabolite isolation and big data-driven measurement uncertainty estimation in proton magnetic resonance spectroscopy of the brain. Magn Reson Med. 2020...
Gastroenterology

TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice

Newsemia
The authors identified a metabolite produced by intestinal bacteria, TMAVA, that worsens fatty liver disease by reducing production of the amino acid carnitine. Carnitine might...

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More

Privacy & Cookies Policy

COVID-19

COVID-19 (Coronavirus) is a new illness that is having a major effect on all businesses globally LIVE COVID-19 STATISTICS FOR World