Tag : Malarial parasites

Biology

EXP1 is critical for nutrient uptake across the parasitophorous vacuole membrane of malaria parasites

Newsemia
by Paolo Mesén-Ramírez, Bärbel Bergmann, Thuy Tuyen Tran, Matthias Garten, Jan Stäcker, Isabel Naranjo-Prado, Katharina Höhn, Joshua Zimmerberg, Tobias Spielmann Intracellular malaria parasites grow in...
Biology

Delayed death in the malaria parasite <i>Plasmodium falciparum</i> is caused by disruption of prenylation-dependent intracellular trafficking

Newsemia
by Kit Kennedy, Simon A. Cobbold, Eric Hanssen, Jakob Birnbaum, Natalie J. Spillman, Emma McHugh, Hannah Brown, Leann Tilley, Tobias Spielmann, Malcolm J. McConville, Stuart...
Biology

Competition for hosts modulates vast antigenic diversity to generate persistent strain structure in <i>Plasmodium falciparum</i>

Newsemia
by Shai Pilosof, Qixin He, Kathryn E. Tiedje, Shazia Ruybal-Pesántez, Karen P. Day, Mercedes Pascual In their competition for hosts, parasites with antigens that are...
Biology

Rapid antigen diversification through mitotic recombination in the human malaria parasite <i>Plasmodium falciparum</i>

Newsemia
by Xu Zhang, Noah Alexander, Irina Leonardi, Christopher Mason, Laura A. Kirkman, Kirk W. Deitsch Malaria parasites possess the remarkable ability to maintain chronic infections...
Biology

Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery

Newsemia
by Avnish Patel, Abigail J. Perrin, Helen R. Flynn, Claudine Bisson, Chrislaine Withers-Martinez, Moritz Treeck, Christian Flueck, Giuseppe Nicastro, Stephen R. Martin, Andres Ramos, Tim...
Biology

Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion

Newsemia
by Christian Flueck, Laura G. Drought, Andrew Jones, Avnish Patel, Abigail J. Perrin, Eloise M. Walker, Stephanie D. Nofal, Ambrosius P. Snijders, Michael J. Blackman,...
Biology

Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites

Newsemia
by Michael J. Boucher, Sreejoyee Ghosh, Lichao Zhang, Avantika Lal, Se Won Jang, An Ju, Shuying Zhang, Xinzi Wang, Stuart A. Ralph, James Zou, Joshua...
Biology

Within-host competition can delay evolution of drug resistance in malaria

Newsemia
by Mary Bushman, Rustom Antia, Venkatachalam Udhayakumar, Jacobus C. de Roode In the malaria parasite P. falciparum, drug resistance generally evolves first in low-transmission settings,...
Biology

<i>Plasmodium vivax</i>-like genome sequences shed new insights into <i>Plasmodium vivax</i> biology and evolution

Newsemia
by Aude Gilabert, Thomas D. Otto, Gavin G. Rutledge, Blaise Franzon, Benjamin Ollomo, Céline Arnathau, Patrick Durand, Nancy D. Moukodoum, Alain-Prince Okouga, Barthélémy Ngoubangoye, Boris...
Biology

<i>Plasmodium vivax</i>-like genome sequences shed new insights into <i>Plasmodium vivax</i> biology and evolution

Newsemia
by Aude Gilabert, Thomas D. Otto, Gavin G. Rutledge, Blaise Franzon, Benjamin Ollomo, Céline Arnathau, Patrick Durand, Nancy D. Moukodoum, Alain-Prince Okouga, Barthélémy Ngoubangoye, Boris...
Biology

Within-host competition can delay evolution of drug resistance in malaria

Newsemia
by Mary Bushman, Rustom Antia, Venkatachalam Udhayakumar, Jacobus C. de Roode In the malaria parasite P. falciparum, drug resistance generally evolves first in low-transmission settings,...

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