Tag: lysosomes

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High ACE2 Expression on pancreatic islet cells during inflammation could explain new-onset diabetes in COVID-19

Newsemia
A new study suggests that the SARS-CoV-2 infection may be linked to the onset of diabetes, via the infection of pancreatic islet beta cells, which...
Pharma / Biotech

Utilising magnetically isolated lysosomes for direct quantification of intralysosomal drug concentrations by LC-MS/MS analysis: An investigatory study with imipramine.

Newsemia
Related Articles Utilising magnetically isolated lysosomes for direct quantification of intralysosomal drug concentrations by LC-MS/MS analysis: An investigatory study with imipramine. J Pharm Sci. 2020...
Biology

Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction

Newsemia
by Ashley L. Comer, Tushare Jinadasa, Balaji Sriram, Rhushikesh A. Phadke, Lisa N. Kretsge, Thanh P. H. Nguyen, Giovanna Antognetti, James P. Gilbert, Jungjoon Lee,...
Biology

Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation

Newsemia
by Victoria E. B. Hipolito, Jacqueline A. Diaz, Kristofferson V. Tandoc, Christian Oertlin, Johannes Ristau, Neha Chauhan, Amra Saric, Shannon Mclaughlan, Ola Larsson, Ivan Topisirovic,...
Biology

Type I interferon limits mast cell–mediated anaphylaxis by controlling secretory granule homeostasis

Newsemia
by Toshihiko Kobayashi, Shiho Shimabukuro-Demoto, Hidemitsu Tsutsui, Noriko Toyama-Sorimachi Type I interferon (IFN-I) is a family of multifunctional cytokines that modulate the innate and adaptive...
Biology

Proteome-wide analysis of chaperone-mediated autophagy targeting motifs

Newsemia
by Philipp Kirchner, Mathieu Bourdenx, Julio Madrigal-Matute, Simoni Tiano, Antonio Diaz, Boris A. Bartholdy, Britta Will, Ana Maria Cuervo Chaperone-mediated autophagy (CMA) contributes to the...
Biology

Reversible association with motor proteins (RAMP): A streptavidin-based method to manipulate organelle positioning

Newsemia
by Carlos M. Guardia, Raffaella De Pace, Aritra Sen, Amra Saric, Michal Jarnik, David A. Kolin, Ambarish Kunwar, Juan S. Bonifacino We report the development...
Biology

Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival

Newsemia
by John T. Murphy, Haiyan Liu, Xiucui Ma, Alex Shaver, Brian M. Egan, Clara Oh, Alexander Boyko, Travis Mazer, Samuel Ang, Rohan Khopkar, Ali Javaheri,...
Gastroenterology

Mieap-induced accumulation of lysosomes within mitochondria (MALM) regulates gastric cancer cell invasion under hypoxia by suppressing reactive oxygen species accumulation

Newsemia
Mieap-induced accumulation of lysosomes within mitochondria (MALM) regulates gastric cancer cell invasion under hypoxia by suppressing reactive oxygen species accumulation Source link...
Dermatology

Staphylococcus aureus from atopic dermatitis skin accumulates in the lysosomes of keratinocytes with induction of IL-1α secretion via TLR9.

Newsemia
Related Articles Staphylococcus aureus from atopic dermatitis skin accumulates in the lysosomes of keratinocytes with induction of IL-1α secretion via TLR9. Allergy. 2018 Sep 30;:...

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