Tag : limits

Pharma / Biotech

P-glycoprotein (ABCB1/MDR1) limits brain accumulation and Cytochrome P450-3A (CYP3A) restricts oral availability of the novel FGFR4 inhibitor fisogatinib (BLU-554).

Newsemia
Related Articles P-glycoprotein (ABCB1/MDR1) limits brain accumulation and Cytochrome P450-3A (CYP3A) restricts oral availability of the novel FGFR4 inhibitor fisogatinib (BLU-554). Int J Pharm. 2019...
Biology

Type I interferon limits mast cell–mediated anaphylaxis by controlling secretory granule homeostasis

Newsemia
by Toshihiko Kobayashi, Shiho Shimabukuro-Demoto, Hidemitsu Tsutsui, Noriko Toyama-Sorimachi Type I interferon (IFN-I) is a family of multifunctional cytokines that modulate the innate and adaptive...
Biology

Developmental delay in shivering limits thermogenic capacity in juvenile high-altitude deer mice (Peromyscus maniculatus) [RESEARCH ARTICLE]

Newsemia
Cayleih E. Robertson and Grant B. McClelland Many endotherms native to cold and hypoxic high-altitude (HA) environments have evolved a highly vascularized and aerobic skeletal...
Biology

Developmental delay in shivering limits thermogenic capacity in juvenile high-altitude deer mice (Peromyscus maniculatus) [RESEARCH ARTICLE]

Newsemia
Cayleih E. Robertson and Grant B. McClelland Many endotherms native to cold and hypoxic high altitude (HA) environments have evolved a highly vascularized and aerobic...
Latest News

The Ecological Limits of Poverty Alleviation in an African Forest-Agriculture Landscape

Newsemia
Morel, AC; Hirons, M; Adu Sasu, M; Quaye, M; Ashley Asare, R; Mason, J; Adu-Bredu, S; … Norris, K; + view all Morel, AC; Hirons,...

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More

Privacy & Cookies Policy