Tag : ligand

Pharma / Biotech

Tuning Ligand Density to Optimize Pharmacokinetics of Targeted Nanoparticles for Dual Protection against Tumor-Induced Bone Destruction.

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Related Articles Tuning Ligand Density to Optimize Pharmacokinetics of Targeted Nanoparticles for Dual Protection against Tumor-Induced Bone Destruction. ACS Nano. 2020 Jan 02;: Authors: Vanderburgh...
Pharma / Biotech

The effect of ligand amount, affinity and internalization on PSMA-targeted imaging and therapy: A simulation study using a PBPK model.

Newsemia
Related Articles The effect of ligand amount, affinity and internalization on PSMA-targeted imaging and therapy: A simulation study using a PBPK model. Sci Rep. 2019...
Dentistry

Serum Flt3 ligand is a biomarker of progenitor cell mass and prognosis in acute myeloid leukemia.

Newsemia
Serum Flt3 ligand is a biomarker of progenitor cell mass and prognosis in acute myeloid leukemia. Blood Adv. 2019 Oct 22;3(20):3052-3061 Authors: Milne P, Wilhelm-Benartzi...
Biology

Resurrection of the ancestral RH5 invasion ligand provides a molecular explanation for the origin of <i>P. falciparum</i> malaria in humans

Newsemia
by Francis Galaway, Ryan Yu, Anastasia Constantinou, Franck Prugnolle, Gavin J. Wright Many important infectious diseases are the result of zoonoses, in which pathogens that...
Pharma / Biotech

Exosome-like nanoplatform modified with targeting ligand improves anti-cancer and anti-inflammation effects of imperialine.

Newsemia
Related Articles Exosome-like nanoplatform modified with targeting ligand improves anti-cancer and anti-inflammation effects of imperialine. J Control Release. 2019 Sep 01;: Authors: Lin Q, Qu...
Cardiology

Number and brightness analysis to study spatio-temporal distribution of the angiotensin II AT1 and the endothelin-1 ETA receptors: Influence of ligand binding.

Newsemia
Related Articles Number and brightness analysis to study spatio-temporal distribution of the angiotensin II AT1 and the endothelin-1 ETA receptors: Influence of ligand binding. Biochim...
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Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission

Newsemia
Rice, HC; de Malmazet, D; Schreurs, A; Frere, S; Van Molle, I; Volkov, AN; Creemers, E; … de Wit, J; + view all Rice, HC;...
Latest News

Scientists identify endogenous activator of sigma-1 receptors in human cells

Newsemia
Cells communicate through complex mechanisms that typically involve receptors and ligands that bind to them. Endogenous ligands, produced by the body, have been identified for...

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