Tag : Knockout

Cardiology

Galectin-3: A Cardiomyocyte Antiapoptotic Mediator at 24-Hour Post Myocardial Infarction.

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Related Articles Galectin-3: A Cardiomyocyte Antiapoptotic Mediator at 24-Hour Post Myocardial Infarction. Cell Physiol Biochem. 2020 Apr 04;54(2):287-302 Authors: Al-Salam S, Hashmi S, Jagadeesh GS,...
Cardiology

Stimulation of Collateral Vessel Growth by Inhibition of Galectin 2 in Mice Using a Single-Domain Llama-Derived Antibody.

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Related Articles Stimulation of Collateral Vessel Growth by Inhibition of Galectin 2 in Mice Using a Single-Domain Llama-Derived Antibody. J Am Heart Assoc. 2019 10...
Cardiology

Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α.

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Related Articles Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α. J Clin Invest. 2020 03 02;130(3):1392-1404 Authors: Siraj MA, Mundil D,...
Cardiology

Compromised Anti-inflammatory Action of Neutrophil Extracellular Traps in PAD4-Deficient Mice Contributes to Aggravated Acute Inflammation After Myocardial Infarction.

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Related Articles Compromised Anti-inflammatory Action of Neutrophil Extracellular Traps in PAD4-Deficient Mice Contributes to Aggravated Acute Inflammation After Myocardial Infarction. Front Immunol. 2019;10:2313 Authors: Eghbalzadeh...
Cardiology

DNA-PKcs promotes cardiac ischemia reperfusion injury through mitigating BI-1-governed mitochondrial homeostasis.

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Related Articles DNA-PKcs promotes cardiac ischemia reperfusion injury through mitigating BI-1-governed mitochondrial homeostasis. Basic Res Cardiol. 2020 01 09;115(2):11 Authors: Zhou H, Toan S, Zhu...
Dermatology

Targeted knockout of β-catenin in adult melanocyte stem cells using a mouse line, Dct::CreERT2, results in disrupted stem cell renewal and pigmentation defects

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Melanocytes (Mc) are pigment-producing cells primarily found in the epidermis and hair follicles, where they transfer melanin to keratinocytes in the inner hair shaft (Colombo...
Cardiology

[Regulatory effect of the zinc transporter Zip2 on cardiomyocyte mitochondrial respiration function after cardiac ischemia-reperfusion injury in mice].

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Related Articles [Regulatory effect of the zinc transporter Zip2 on cardiomyocyte mitochondrial respiration function after cardiac ischemia-reperfusion injury in mice]. Sheng Li Xue Bao. 2020...
Neurology

Deletion of a Neuronal Drp1 Activator Protects against Cerebral Ischemia.

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Related Articles Deletion of a Neuronal Drp1 Activator Protects against Cerebral Ischemia. J Neurosci. 2020 04 08;40(15):3119-3129 Authors: Flippo KH, Lin Z, Dickey AS, Zhou...
Cardiology

Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction.

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Related Articles Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction. JCI Insight. 2019 08 22;4(16): Authors: Sandireddy R, Cibi DM, Gupta P, Singh A,...
Cardiology

Inactivation of Sox9 in fibroblasts reduces cardiac fibrosis and inflammation.

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Related Articles Inactivation of Sox9 in fibroblasts reduces cardiac fibrosis and inflammation. JCI Insight. 2019 07 16;5: Authors: Scharf GM, Kilian K, Cordero J, Wang...
Cardiology

Fibroblast-specific deletion of interleukin-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction.

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Related Articles Fibroblast-specific deletion of interleukin-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction. JCI Insight. 2019 08 08;5: Authors: Bageghni SA, Hemmings KE, Yuldasheva...
Cardiology

Pressure overload leads to coronary plaque formation, progression, and myocardial events in ApoE-/- mice.

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Related Articles Pressure overload leads to coronary plaque formation, progression, and myocardial events in ApoE-/- mice. JCI Insight. 2019 05 02;4(9): Authors: Marino A, Zhang...
Cardiology

O-GlcNAc Transferase Promotes Compensated Cardiac Function and Protein Kinase A O-GlcNAcylation During Early and Established Pathological Hypertrophy From Pressure Overload.

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Related Articles O-GlcNAc Transferase Promotes Compensated Cardiac Function and Protein Kinase A O-GlcNAcylation During Early and Established Pathological Hypertrophy From Pressure Overload. J Am Heart...
Dentistry

6-[124I]Iodo-9-pentylpurine for Imaging the Activity of the Sodium Iodide Symporter in the Brain.

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Related Articles 6-[124I]Iodo-9-pentylpurine for Imaging the Activity of the Sodium Iodide Symporter in the Brain. J Med Chem. 2020 02 27;63(4):1717-1723 Authors: Okamura T, Tsukamoto...
Cardiology

Role of Ryanodine Type 2 Receptors in Elementary Ca2+ Signaling in Arteries and Vascular Adaptive Responses.

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Related Articles Role of Ryanodine Type 2 Receptors in Elementary Ca2+ Signaling in Arteries and Vascular Adaptive Responses. J Am Heart Assoc. 2019 05 07;8(9):e010090...

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