Dual Activities of Receptor-Like Kinase OsWAKL21.2 Induce Immune Responses
Plant pathogens secrete cell wall-degrading enzymes that degrade various components of the plant cell wall. Plants sense this cell wall damage as a mark of...
Tag: Kinase
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase Source link...
Arabidopsis Lectin Receptor Kinase P2K2 Is a Second Plant Receptor for Extracellular ATP and Contributes to Innate Immunity
In animals, extracellular ATP is a well-studied signaling molecule that is recognized by plasma membrane-localized P2-type purinergic receptors. However, in contrast, much less is known...
New platform prioritizes synergistic drug combinations against SARS-CoV-2
Researchers in the U.S. have used a new web-based platform to help identify synergistic and antagonistic drug combinations and their underlying mechanisms of action in...
Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical β-catenin-dependent mechanism
Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical β-catenin-dependent mechanism Source link...
Clinically approved drugs could disrupt SARS-CoV-2 from hijacking Cells
An international team of researchers has analyzed how SARS-CoV-2, the virus that causes COVID-19, hijacks the proteins in its target cells. Source link...
Combined effects of AKT serine/threonine kinase 1 polymorphisms and environment on congenital heart disease risk: A case-control study.
Related Articles Combined effects of AKT serine/threonine kinase 1 polymorphisms and environment on congenital heart disease risk: A case-control study. Medicine (Baltimore). 2020 Jun 26;99(26):e20400...
Structural and functional analysis of the fission yeast Sty1 stress-activated MAP kinase pathway
Wilkinson, Marc G.; (1998) Structural and functional analysis of the fission yeast Sty1 stress-activated MAP kinase pathway. Doctoral thesis (Ph.D), UCL (University College London). Green...
Nocodazole-Induced Expression and Phosphorylation of Anillin and Other Mitotic Proteins Are Decreased in DNA-Dependent Protein Kinase Catalytic Subunit-Deficient Cells and Rescued by Inhibition of the Anaphase-Promoting Complex/Cyclosome with proTAME but Not Apcin [Research Article]
The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) has well-established roles in DNA double-strand break repair, and recently, nonrepair functions have also been reported. To better...
Pediatric high-grade glioma: aberrant epigenetics and kinase signaling define emerging therapeutic opportunities.
Related Articles Pediatric high-grade glioma: aberrant epigenetics and kinase signaling define emerging therapeutic opportunities. J Neurooncol. 2020 Jun 05;: Authors: Sun Y, Bailey CP, Sadighi...
New strategy identified to address the underlying cause of LAD1 patients' symptoms
Owing to a rare genetic mutation, individuals with leukocyte adhesion deficiency type 1 (LAD1) experience a suite of symptoms that trace back to an immune...
Researchers find a 'skinny' gene
Some people may have trouble losing weight, while others find it hard to gain weight. Now, a team of scientists may have found the answer...
Protein Kinase D1, Reduced in Human Pancreatic Tumors, Increases Secretion of Small Extracellular Vesicles From Cancer Cells That Promote Metastasis to Lung in Mice
Pancreatic tumor cells release extracellular vesicles (sEVs, exosomes) that contain lipids and proteins, RNA, and DNA molecules might promote formation of metastases. It is not...
Calcium-Dependent Protein Kinase CPK1 Controls Cell Death by In Vivo Phosphorylation of Senescence Master Regulator ORE1
Calcium-regulated protein kinases are key components of intracellular signaling in plants that mediate rapid stress-induced responses to changes in the environment. To identify in vivo...
Adenosine kinase and adenosine receptors A1 R and A2A R in temporal lobe epilepsy and hippocampal sclerosis and association with risk factors for SUDEP.
Patodia, S; Paradiso, B; Garcia, M; Ellis, M; Diehl, B; Thom, M; Devinsky, O; (2020) Adenosine kinase and adenosine receptors A1 R and A2A R...
CME Exam 3: Safety of Janus Kinase Inhibitors in Patients With Inflammatory Bowel Diseases or Other Immune-mediated Diseases: A Systematic Review and Meta-analysis
CME Exam 3: Safety of Janus Kinase Inhibitors in Patients With Inflammatory Bowel Diseases or Other Immune-mediated Diseases: A Systematic Review and Meta-analysis Source link...