Tag: Kinase

Biology

Genetic Analyses of the Arabidopsis ATG1 Kinase Complex Reveal Both Kinase-Dependent and Independent Autophagic Routes during Fixed-Carbon Starvation

Newsemia
Under nutrient and energy-limiting conditions, plants up-regulate sophisticated catabolic pathways such as autophagy to remobilize nutrients and restore energy homeostasis. Autophagic flux is tightly regulated...
Latest News

Irutinib-based therapy provides superior clinical outcomes in majority of CLL patients

Newsemia
The ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) today announced results from an extended follow-up analysis of patients in its randomized Phase 3 clinical trial, E1912. Source...
Latest News

Janus kinase inhibition for autoinflammation in DNASE2 deficiency

Newsemia
Hong, Y; Capitani, M; Murphy, C; Pandey, S; Cavounidis, A; Takeshita, H; Nanthapisal, S; … Brogan, P; + view all Hong, Y; Capitani, M; Murphy,...
Latest News

ICR scientists carry out first comprehensive assessment of chemical probe resources

Newsemia
A new report urges biomedical researchers to use online web resources very carefully, taking into account their complementary benefits and weaknesses, when selecting small-molecule chemical...
Pharma / Biotech

A phase 1 dose-escalation study of checkpoint kinase 1 (CHK1) inhibitor prexasertib in combination with p38 mitogen-activated protein kinase (p38 MAPK) inhibitor ralimetinib in patients with advanced or metastatic cancer.

Newsemia
Related Articles A phase 1 dose-escalation study of checkpoint kinase 1 (CHK1) inhibitor prexasertib in combination with p38 mitogen-activated protein kinase (p38 MAPK) inhibitor ralimetinib...
Biology

Correction of Glycogen Synthase Kinase 3{beta} in Myotonic Dystrophy 1 Reduces the Mutant RNA and Improves Postnatal Survival of DMSXL Mice [Research Article]

Newsemia
Myotonic dystrophy type 1 (DM1) is a multisystem neuromuscular disease without cure. One of the possible therapeutic approaches for DM1 is correction of the RNA-binding...
Pharma / Biotech

Hypoxia-selective radiosensitisation by SN38023, a bioreductive prodrug of DNA-dependent protein kinase inhibitor IC87361.

Newsemia
Related Articles Hypoxia-selective radiosensitisation by SN38023, a bioreductive prodrug of DNA-dependent protein kinase inhibitor IC87361. Biochem Pharmacol. 2019 Sep 18;:113641 Authors: Wong WW, Jackson RK,...

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More

Privacy & Cookies Policy