Tag : irreversible

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Phase I, first-in-human study of futibatinib, a highly selective, irreversible FGFR1-4 inhibitor in patients with advanced solid tumors

Newsemia
Bahleda, R; Meric-Bernstam, F; Goyal, L; Tran, B; He, Y; Yamamiya, I; Benhadji, KA; … Arkenau, H-T; + view all Bahleda, R; Meric-Bernstam, F; Goyal,...
Neurology

Irreversible neuropathy in extremely-drug resistant tuberculosis: An unfortunate clinical conundrum.

Newsemia
Related Articles Irreversible neuropathy in extremely-drug resistant tuberculosis: An unfortunate clinical conundrum. Indian J Tuberc. 2020 Jul;67(3):389-392 Authors: Saroha D, Garg D, Singh AK, Dhamija...
Dentistry

Bilateral mental incisive nerve block probably has a higher success rate than unilateral mental incisive nerve block in mandibular incisors with irreversible pulpitis.

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Related Articles Bilateral mental incisive nerve block probably has a higher success rate than unilateral mental incisive nerve block in mandibular incisors with irreversible pulpitis....
Pharma / Biotech

Safety, Pharmacokinetics and Pharmacodynamics of Branebrutinib (BMS-986195), a Covalent, Irreversible Inhibitor of Bruton's Tyrosine Kinase: Randomised Phase I, Placebo-Controlled Trial in Healthy Participants.

Newsemia
Safety, Pharmacokinetics and Pharmacodynamics of Branebrutinib (BMS-986195), a Covalent, Irreversible Inhibitor of Bruton’s Tyrosine Kinase: Randomised Phase I, Placebo-Controlled Trial in Healthy Participants. Br J...
Dentistry

Different anesthetics on the efficacy of inferior alveolar nerve block in patients with irreversible pulpitis: A network systematic review and meta-analysis.

Newsemia
Related Articles Different anesthetics on the efficacy of inferior alveolar nerve block in patients with irreversible pulpitis: A network systematic review and meta-analysis. J Am...
Dentistry

Cryotherapy may increase the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis who undergo endodontic treatment.

Newsemia
Related Articles Cryotherapy may increase the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis who undergo endodontic treatment. J Am...
Dentistry

Local infiltration of corticosteroids may decrease pain 48 hours after 1-visit endodontic treatment in patients with irreversible pulpitis.

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Related Articles Local infiltration of corticosteroids may decrease pain 48 hours after 1-visit endodontic treatment in patients with irreversible pulpitis. J Am Dent Assoc. 2019...
Dentistry

Cold treatment as an adjunct to inferior alveolar nerve block may reduce pain and anxiety in patients undergoing endodontic treatment in mandibular molars with symptomatic irreversible pulpitis.

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Related Articles Cold treatment as an adjunct to inferior alveolar nerve block may reduce pain and anxiety in patients undergoing endodontic treatment in mandibular molars...
Biology

Irreversible Activation of Rho-activated Kinases Resulted from Evolution of Proteolytic Sites within Disordered Regions in Coiled-coil Domain

Newsemia
Abstract Activation of Rho-associated protein kinase 1 (ROCK1) and myotonic dystrophy kinase-related CDC42-binding kinase alpha (MRCKα) by caspases during apoptosis in vertebrates represents a prototypical...
Dentistry

There seem to be no important differences in the effects of inferior alveolar nerve block and mental incisal nerve block when treating patients with irreversible pulpitis in mandibular premolars.

Newsemia
Related Articles There seem to be no important differences in the effects of inferior alveolar nerve block and mental incisal nerve block when treating patients...

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