Tag : Interferons

Biology

Type I interferon limits mast cell–mediated anaphylaxis by controlling secretory granule homeostasis

Newsemia
by Toshihiko Kobayashi, Shiho Shimabukuro-Demoto, Hidemitsu Tsutsui, Noriko Toyama-Sorimachi Type I interferon (IFN-I) is a family of multifunctional cytokines that modulate the innate and adaptive...
Biology

Extensive editing of cellular and viral double-stranded RNA structures accounts for innate immunity suppression and the proviral activity of ADAR1<sup>p150</sup>

Newsemia
by Christian K. Pfaller, Ryan C. Donohue, Stepan Nersisyan, Leonid Brodsky, Roberto Cattaneo The interferon (IFN)-mediated innate immune response is the first line of defense...
Biology

In vitro–transcribed guide RNAs trigger an innate immune response via the RIG-I pathway

Newsemia
by Beeke Wienert, Jiyung Shin, Elena Zelin, Kathleen Pestal, Jacob E. Corn Clustered, regularly interspaced, short palindromic repeat (CRISPR)–CRISPR-associated 9 (Cas9) genome editing is revolutionizing...

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