Tag: Integrin

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Evaluation of receptor-mediated gene transfer using an integrin -targeting vector as a potential form of therapy for lysosomal storage diseases

Newsemia
White, Elaine Joanna; (2000) Evaluation of receptor-mediated gene transfer using an integrin -targeting vector as a potential form of therapy for lysosomal storage diseases. Doctoral...
Latest News

Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells

Newsemia
Kolev, M; West, EE; Kunz, N; Chauss, D; Moseman, EA; Rahman, J; Freiwald, T; … Kemper, C; + view all Kolev, M; West, EE; Kunz,...
Gastroenterology

SPOCK1 overexpression induced by platelet-derived growth factor-BB promotes hepatic stellate cell activation and liver fibrosis through the integrin α5β1/PI3K/Akt signaling pathway

Newsemia
SPOCK1 overexpression induced by platelet-derived growth factor-BB promotes hepatic stellate cell activation and liver fibrosis through the integrin α5β1/PI3K/Akt signaling pathway Source link...
Latest News

A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor

Newsemia
Maher, TM; Simpson, JK; Porter, JC; Wilson, FJ; Chan, R; Eames, R; Cui, Y; … Vahdati-Bolouri, M; + view all Maher, TM; Simpson, JK; Porter,...
Gastroenterology

ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells

Newsemia
Pancreatic tumors undergo rapid growth and progression, become resistant to chemotherapy, and recur after surgery. We studied the functions of the solute carrier family 39...
Gastroenterology

GLI1 activation by non-classical pathway integrin αvβ3/ERK1/2 maintains stem cell-like phenotype of multicellular aggregates in gastric cancer peritoneal metastasis

Newsemia
GLI1 activation by non-classical pathway integrin αvβ3/ERK1/2 maintains stem cell-like phenotype of multicellular aggregates in gastric cancer peritoneal metastasis Source link...
Pharma / Biotech

Preclinical evaluation of peptide-based radiotracers for integrin αvβ6-positive pancreatic carcinoma.

Newsemia
Related Articles Preclinical evaluation of peptide-based radiotracers for integrin αvβ6-positive pancreatic carcinoma. Nuklearmedizin. 2019 May 10;: Authors: Müller M, Altmann A, Sauter M, Lindner T,...
Biology

Intramembrane ionic protein–lipid interaction regulates integrin structure and function

Newsemia
by Jun Guo, Youhua Zhang, Hua Li, Huiying Chu, Qinshu Wang, Shutan Jiang, Yan Li, Hongbin Shen, Guohui Li, Jianfeng Chen, Chenqi Xu Protein transmembrane...
Neurology

Synthetic α5β1 integrin ligand PHSRN is proangiogenic and neuroprotective in cerebral ischemic stroke.

Newsemia
Related Articles Synthetic α5β1 integrin ligand PHSRN is proangiogenic and neuroprotective in cerebral ischemic stroke. Biomaterials. 2018 Sep 11;185:142-154 Authors: Wu CC, Wang LC, Su...
Biology

A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and α<sub>v</sub>β<sub>3</sub> integrin for osteoporosis therapy

Newsemia
by Yuval Zur, Lior Rosenfeld, Chen Anna Keshelman, Nofar Dalal, Gali Guterman-Ram, Ayelet Orenbuch, Yulia Einav, Noam Levaot, Niv Papo There is currently a demand...
Biology

A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and α<sub>v</sub>β<sub>3</sub> integrin for osteoporosis therapy

Newsemia
by Yuval Zur, Lior Rosenfeld, Chen Anna Keshelman, Nofar Dalal, Gali Guterman-Ram, Ayelet Orenbuch, Yulia Einav, Noam Levaot, Niv Papo There is currently a demand...

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