Impairment
- December 7, 2019
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- Tags: AlleleApolipoproteinChinesecognitivedementiaImpairmentPopulationVascularε4
The association between apolipoprotein E (APOE) ε4 allele and vascular cognitive impairment no dementia (VCIND) is still controversial. Source link
Read more- December 3, 2019
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- Tags: Alzheimer’s disease;Dementia;Machine learning;Mild cognitive impairment;Neuropsychological testcognitiveDataDeepImpairmentlearningmulticenterNeuropsychologicalPredictiontesttrained
Related Articles Prediction of cognitive impairment via deep learning trained with multi-center neuropsychological test data. BMC Med Inform Decis Mak. 2019 Nov 21;19(1):231 Authors: Kang MJ, Kim SY, Na DL,...
Read more- November 25, 2019
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- Tags: AttendingbrainChronic Diseasechronic illnessclinical researchclinical studiesclinical trialsfallsFrustrationsImpairmentinjurymood swingsmovement disordermuscular atrophiesMuscular AtrophyNeurodegenerative DiseasePalsyprognosisProgressiveProgressive Supranuclear Palsysteele-richardson-olszewski syndromeSupranuclearthought disorder
PSP is a rare neurogenerative disorder that is increasingly appreciated among neurologists. Yet effective treatments remain elusive. Medscape Neurology Source link
Read more- November 25, 2019
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- Tags: ClinicaldotinuradDotinurad;Hepatic impairment;Pharmacodynamics;Pharmacokinetics;Selective urate reabsorption inhibitor (SURI);URAT1 inhibitorhepaticImpairmentInhibitorpharmacokineticreabsorptionselectivestudysubjectsurate
Related Articles Dotinurad: a clinical pharmacokinetic study of a novel, selective urate reabsorption inhibitor in subjects with hepatic impairment. Clin Exp Nephrol. 2019 Nov 23;: Authors: Kumagai Y, Sakaki M,...
Read more- November 24, 2019
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- Tags: cognitiveculpritImpairmentProtectiveStatins
Statins and Cognitive Impairment: Not a Culprit, Protective in Some? Source link
Read moreThe FDA approved changes to the product labels for direct-acting antivirals Harvoni, Epclusa, and Vosevi to include new efficacy and safety data for adults with hepatitis C and severe renal...
Read more- November 20, 2019
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- Tags: AIFM1ataxicHearingImpairmentJapaneseMissenseMutationneuronopathyPatientsensory
Apoptosis-Inducing Factor Mitochondria-associated-1 gene (AIFM1) encodes a mitochondrial flavin adenine dinucleotide-dependent nicotinamide oxidoreductase, which has a biological role in oxidative phosphorylation (OXPHOS) and in apoptosis pathway [1]. AIFM1 mutations have...
Read more- November 15, 2019
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- Tags: departmentemergencyfunctionalfunctional disabilityheadacheheadachesImpairmentneurologyOutcomePediatricspredictspsychologyYouth
Clinical Pediatrics, Ahead of Print. Headache is a common presenting complaint in emergency departments (EDs), with the goal of improving acute pain. However, youth with chronic headaches may demonstrate broad...
Read more- November 13, 2019
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- Tags: analysisbloodCerebralCitation searchcognitiveDeepEntrezflowFrailtyHIVIdentifyImpairmentJournal ArticleslearningLivingMedical JournalsMEDLINENational Center for Biotechnology InformationNCBINLMPersonspub medPubMedUnited States National Library of Medicine
Deep Learning Analysis of Cerebral Blood Flow to Identify Cognitive Impairment and Frailty in Persons Living With HIV. J Acquir Immune Defic Syndr. 2019 Dec 15;82(5):496-502 Authors: Luckett P, Paul...
Read more- November 11, 2019
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- Tags: DetectselderlyencephalopathyhepaticImpairmentMinimalTool
BOSTON — In a multicenter study of older patients with cirrhosis, the EncephalApp tool accurately diagnosed cognitive impairment and hepatic encephalopathy, according to a presenter at The Liver Meeting 2019.“Patients...
Read more- November 10, 2019
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- Tags: #healthAdultsapplicationdiseaseEndstageImpairmentLanguageLanguage;Liver diseases;Machine learning;Neurological manifestationslivernaturalPatientGeneratedprocessingrecords
Related Articles Language impairment in adults with end-stage liver disease: application of natural language processing towards patient-generated health records. NPJ Digit Med. 2019;2:106 Authors: Dickerson LK, Rouhizadeh M, Korotkaya Y,...
Read more- November 4, 2019
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- Tags: #healthAdultsapplicationdiseaseEndstageImpairmentLanguagelivernaturalPatientGeneratedprocessingrecords
Language impairment in adults with end-stage liver disease: application of natural language processing towards patient-generated health records Source link
Read more- November 4, 2019
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- Tags: cognitivediethigh-saltHighsaltImpairmentPathogenicPrecipitatedtau
High levels of dietary salt can activate a pathway in the brain to cause cognitive impairment, according to a new study. The paper, published in Nature, shows that this effect is not due...
Read more- October 28, 2019
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- Tags: adolescent medicineantigensapprovesbiologic therapyBotoxbotulinum toxinCerebral PalsyCHILDChildhoodchildrenFDAhealth-related quality of lifeHRQOLImpairmentkidsLowerLimbPediatricsQOLquality of lifespasticityu.s. food and drug administrationunited states food and drug administration
The FDA has approved Botox to ease lower-limb spasticity in children and adolescents aged 2 to 17 years, excluding spasticity caused by cerebral palsy. FDA Approvals Source link
Read more- October 28, 2019
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- Tags: classificationcognitivedementiadiseaseHuntington’sImpairmentManifestMildmotorprevalence
Congratulations Drs. ParunyouJulayanont, Nikolaus R.McFarland, and Kenneth M.Heilman on the publication of “Mild cognitive impairment and dementia in motor manifest Huntington’s disease: Classification and prevalence,” which was published in the...
Read more- October 25, 2019
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- Tags: childrenImpairmentneurologicpneumoniapreventionstrategies
BACKGROUND: Children with neurologic impairment (NI) face high risk of recurrent severe pneumonia, with prevention strategies of unknown effectiveness. We evaluated the comparative effectiveness of secondary prevention strategies for severe...
Read more- October 23, 2019
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- Tags: ActivatebloodBlood Vesselblood vesselsbraincognitivedementiadietdietaryHighImpairmentlevelsMedical ResearchmedicineNervous SystempathwaypHproteinresearchsaltstrokeTau Protein
High levels of dietary salt can activate a pathway in the brain to cause cognitive impairment, according to a new study. The paper, which was published in Nature, shows that...
Read more- October 18, 2019
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- Tags: AbilityAsiaAssessingautonomicbasedBladderBoweldocumentfunctionImpairmentSacralScalestandards
Assessing the ability of the Sacral Autonomic Standards to document bladder and bowel function based upon the Asia Impairment Scale Source link
Read more- October 17, 2019
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- Tags: cognitiveImpairmentimprovementmeasurementMildneurologyqualitySet
Mild cognitive impairment (MCI) is a syndrome increasingly recognized in older adults and has become a major focus of clinical care and research. MCI is used to describe acquired objective...
Read moreLondon—Approximately one-third of young cancer patients show significant cognitive declines, but the adverse effect does not seem to be solely related to chemotherapy. Source link
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