Impairment

Apolipoprotein E ε4 allele is associated with vascular cognitive impairment no dementia in Chinese population

The association between apolipoprotein E (APOE) ε4 allele and vascular cognitive impairment no dementia (VCIND) is still controversial. Source link

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Prediction of cognitive impairment via deep learning trained with multi-center neuropsychological test data.

Related Articles Prediction of cognitive impairment via deep learning trained with multi-center neuropsychological test data. BMC Med Inform Decis Mak. 2019 Nov 21;19(1):231 Authors: Kang MJ, Kim SY, Na DL,...

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The Falls and Frustrations of Progressive Supranuclear Palsy

PSP is a rare neurogenerative disorder that is increasingly appreciated among neurologists. Yet effective treatments remain elusive. Medscape Neurology Source link

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Dotinurad: a clinical pharmacokinetic study of a novel, selective urate reabsorption inhibitor in subjects with hepatic impairment.

Related Articles Dotinurad: a clinical pharmacokinetic study of a novel, selective urate reabsorption inhibitor in subjects with hepatic impairment. Clin Exp Nephrol. 2019 Nov 23;: Authors: Kumagai Y, Sakaki M,...

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Statins and Cognitive Impairment: Not a Culprit, Protective in Some?

Statins and Cognitive Impairment: Not a Culprit, Protective in Some? Source link

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Gilead DAAs safe, effective for adults with HCV, severe renal impairment

The FDA approved changes to the product labels for direct-acting antivirals Harvoni, Epclusa, and Vosevi to include new efficacy and safety data for adults with hepatitis C and severe renal...

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A novel AIFM1 missense mutation in a Japanese patient with ataxic sensory neuronopathy and hearing impairment

Apoptosis-Inducing Factor Mitochondria-associated-1 gene (AIFM1) encodes a mitochondrial flavin adenine dinucleotide-dependent nicotinamide oxidoreductase, which has a biological role in oxidative phosphorylation (OXPHOS) and in apoptosis pathway [1]. AIFM1 mutations have...

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Functional Impairment Predicts Outcome of Youth With Headache in the Emergency Department

Clinical Pediatrics, Ahead of Print. Headache is a common presenting complaint in emergency departments (EDs), with the goal of improving acute pain. However, youth with chronic headaches may demonstrate broad...

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Deep Learning Analysis of Cerebral Blood Flow to Identify Cognitive Impairment and Frailty in Persons Living With HIV.

Deep Learning Analysis of Cerebral Blood Flow to Identify Cognitive Impairment and Frailty in Persons Living With HIV. J Acquir Immune Defic Syndr. 2019 Dec 15;82(5):496-502 Authors: Luckett P, Paul...

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Hepatic encephalopathy tool detects minimal impairment in the elderly

BOSTON — In a multicenter study of older patients with cirrhosis, the EncephalApp tool accurately diagnosed cognitive impairment and hepatic encephalopathy, according to a presenter at The Liver Meeting 2019.“Patients...

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Language impairment in adults with end-stage liver disease: application of natural language processing towards patient-generated health records.

Related Articles Language impairment in adults with end-stage liver disease: application of natural language processing towards patient-generated health records. NPJ Digit Med. 2019;2:106 Authors: Dickerson LK, Rouhizadeh M, Korotkaya Y,...

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Language impairment in adults with end-stage liver disease: application of natural language processing towards patient-generated health records

Language impairment in adults with end-stage liver disease: application of natural language processing towards patient-generated health records Source link

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Pathogenic tau and cognitive impairment are precipitated by a high-salt diet

High levels of dietary salt can activate a pathway in the brain to cause cognitive impairment, according to a new study. The paper, published in Nature, shows that this effect is not due...

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FDA Approves Botox for Lower-Limb Spasticity in Children

The FDA has approved Botox to ease lower-limb spasticity in children and adolescents aged 2 to 17 years, excluding spasticity caused by cerebral palsy. FDA Approvals Source link

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Mild cognitive impairment and dementia in motor manifest Huntington’s disease: Classification and prevalence

Congratulations Drs. ParunyouJulayanont, Nikolaus R.McFarland, and Kenneth M.Heilman on the publication of “Mild cognitive impairment and dementia in motor manifest Huntington’s disease: Classification and prevalence,” which was published in the...

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Pneumonia Prevention Strategies for Children With Neurologic Impairment

BACKGROUND: Children with neurologic impairment (NI) face high risk of recurrent severe pneumonia, with prevention strategies of unknown effectiveness. We evaluated the comparative effectiveness of secondary prevention strategies for severe...

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High levels of dietary salt can activate a brain pathway to cause cognitive impairment

High levels of dietary salt can activate a pathway in the brain to cause cognitive impairment, according to a new study. The paper, which was published in Nature, shows that...

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Assessing the ability of the Sacral Autonomic Standards to document bladder and bowel function based upon the Asia Impairment Scale

Assessing the ability of the Sacral Autonomic Standards to document bladder and bowel function based upon the Asia Impairment Scale Source link

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Quality improvement in neurology: Mild cognitive impairment quality measurement set

Mild cognitive impairment (MCI) is a syndrome increasingly recognized in older adults and has become a major focus of clinical care and research. MCI is used to describe acquired objective...

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Cognitive Impairment Among Young Cancer Patients A Real Concern

London—Approximately one-third of young cancer patients show significant cognitive declines, but the adverse effect does not seem to be solely related to chemotherapy. Source link

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