immune response

Detecting T cell receptors involved in immune responses from single repertoire snapshots

by Mikhail V. Pogorelyy, Anastasia A. Minervina, Mikhail Shugay, Dmitriy M. Chudakov, Yuri B. Lebedev, Thierry Mora, Aleksandra M. Walczak Hypervariable T cell receptors (TCRs) play a key role in...

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Researchers propose a new look at the role of ferroptosis in cancer development

Professor of Ghent University and Lead Researcher at the Institute of Biology and Biomedicine of the Lobachevsky University Dmitri Krysko together with scientists from Germany, Professor Marcus Conrad and Professor...

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Scientists 'on the right track' toward universal flu vaccine

New research could bring scientists a step closer to developing an effective, universal flu vaccine. Source link

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Findings provide new insights about how intestine maximizes nutrient uptake

As food enters the intestine, it embarks on windy, lengthy journey. For most of the route, its surroundings don't appear to change much. Source link

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UT Southwestern study suggests why UTIs have high recurrence rate in postmenopausal women

[ad_1] A UT Southwestern study suggests why urinary tract infections have such a high recurrence rate in postmenopausal women - several species of bacteria can invade the bladder walls. Source...

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Scientists discover biological barrier that keeps cancer at bay

[ad_1] Activins are proteins involved in a number of important biological functions, including the regulation of the menstrual cycle, cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and...

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Angiotensin receptor blockers could improve response to cancer immunotherapy

[ad_1] A research team led by investigators at Massachusetts General Hospital and the Massachusetts Institute of Technology has found that combining a specialized version of an antihypertension drug with immune...

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New study defines antibody characteristics of plasmablasts during Kawasaki Disease

[ad_1] A new study looks to define the antibody characteristics, including clonality, of plasmablasts during Kawasaki Disease. Source link [ad_2]

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Low-dose radiation therapy may increase uptake of therapeutic nanoparticles by brain tumors

A new study led by Massachusetts General Hospital (MGH) investigators finds that radiation therapy may increase the uptake of therapeutic nanoparticles by glioblastomas, raising the possibility of using both growth-factor-targeted...

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Aging and high-fat diet disrupt gut microbiome to cause inflammation in heart failure

[ad_1] Growing older and a high-fat diet enriched with omega 6 fatty acids are major contributors to health risks ranging from diabetes to heart failure. How these two factors regulate...

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High-Fiber Diet May Help Your Gut Battle Melanoma

[ad_1] New research suggests that a diet that's full of fiber appears to lead to more diverse intestinal bacteria (microbiome). In turn, a thriving gut microbiome is linked to a...

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Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen

[ad_1] by Fabian Sesterhenn, Marie Galloux, Sabrina S. Vollers, Lucia Csepregi, Che Yang, Delphyne Descamps, Jaume Bonet, Simon Friedensohn, Pablo Gainza, Patricia Corthésy, Man Chen, Stéphane Rosset, Marie-Anne Rameix-Welti, Jean-François...

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Single CRISPR treatment can safely and stably correct genetic disease

[ad_1] Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease -- Duchenne muscular dystrophy (DMD)...

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Castration-resistant metastatic prostate cancer responds to combination of immune checkpoint inhibitors

[ad_1] Some patients with metastatic prostate cancer respond to a combination of immune checkpoint inhibitors after hormonal therapy and chemotherapy have failed, according to early results from a clinical trial...

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Powerful immune molecule silences barrel to protect transplanted organs from rejection

[ad_1] A powerful immune molecule helps protect transplanted organs from rejection by putting a silencer on two other immune molecules that converge to take a direct shot at the organ,...

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Scientists explore new treatment targets for retinal damage

[ad_1] Scientists at the Medical College of Georgia at Augusta University are looking at new treatment targets for the retinal damage that often accompanies diseases like diabetes, glaucoma and hypertension....

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NIAID-funded clinical trial of Ebola vaccines is underway at Cincinnati Children's

[ad_1] A Phase 1 clinical trial of investigational vaccines intended to protect against Zaire ebolavirus (Ebola) is underway at Cincinnati Children's Hospital Medical Center in the United States. The study...

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Clinical testing begins for temperature-stable experimental tuberculosis vaccine

[ad_1] Vaccinations have begun in a Phase 1 human clinical trial testing a freeze-dried, temperature-stable formulation of an experimental tuberculosis vaccine candidate. Source link [ad_2]

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New potential immunotherapy target in pancreatic cancer identified

[ad_1] Researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety...

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Study finds specific function of HIV protein that slows down viral spread

[ad_1] A study from a Massachusetts General Hospital research team has identified the specific function of a protein found in HIV and related viruses that appears to slow down viral...

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