immune response

Single CRISPR treatment can safely and stably correct genetic disease

[ad_1] Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease -- Duchenne muscular dystrophy (DMD)...

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Castration-resistant metastatic prostate cancer responds to combination of immune checkpoint inhibitors

[ad_1] Some patients with metastatic prostate cancer respond to a combination of immune checkpoint inhibitors after hormonal therapy and chemotherapy have failed, according to early results from a clinical trial...

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Powerful immune molecule silences barrel to protect transplanted organs from rejection

[ad_1] A powerful immune molecule helps protect transplanted organs from rejection by putting a silencer on two other immune molecules that converge to take a direct shot at the organ,...

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Scientists explore new treatment targets for retinal damage

[ad_1] Scientists at the Medical College of Georgia at Augusta University are looking at new treatment targets for the retinal damage that often accompanies diseases like diabetes, glaucoma and hypertension....

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NIAID-funded clinical trial of Ebola vaccines is underway at Cincinnati Children's

[ad_1] A Phase 1 clinical trial of investigational vaccines intended to protect against Zaire ebolavirus (Ebola) is underway at Cincinnati Children's Hospital Medical Center in the United States. The study...

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Clinical testing begins for temperature-stable experimental tuberculosis vaccine

[ad_1] Vaccinations have begun in a Phase 1 human clinical trial testing a freeze-dried, temperature-stable formulation of an experimental tuberculosis vaccine candidate. Source link [ad_2]

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New potential immunotherapy target in pancreatic cancer identified

[ad_1] Researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety...

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Study finds specific function of HIV protein that slows down viral spread

[ad_1] A study from a Massachusetts General Hospital research team has identified the specific function of a protein found in HIV and related viruses that appears to slow down viral...

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Expression of a molecule in blood cells inversely predicts appearance of subclinical atherosclerosis

[ad_1] Earlier detection of cardiovascular disease is a step closer thanks to the findings of a research team at the Centro Nacional de Investigaciones Cardiovasculares led by Francisco Sánchez-Madrid and...

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Integrative network-centric approach reveals signaling pathways associated with plant resistance and susceptibility to <i>Pseudomonas syringae</i>

[ad_1] by Elizabeth K. Brauer, George V. Popescu, Dharmendra K. Singh, Mauricio Calviño, Kamala Gupta, Bhaskar Gupta, Suma Chakravarthy, Sorina C. Popescu Plant protein kinases form redundant signaling pathways to...

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Timescales of influenza A/H3N2 antibody dynamics

by Adam J. Kucharski, Justin Lessler, Derek A. T. Cummings, Steven Riley Human immunity influences the evolution and impact of influenza strains. Because individuals are infected with multiple influenza strains...

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Timescales of influenza A/H3N2 antibody dynamics

by Adam J. Kucharski, Justin Lessler, Derek A. T. Cummings, Steven Riley Human immunity influences the evolution and impact of influenza strains. Because individuals are infected with multiple influenza strains...

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KDM5 histone demethylases repress immune response via suppression of STING

by Lizhen Wu, Jian Cao, Wesley L. Cai, Sabine M. Lang, John R. Horton, Daniel J. Jansen, Zongzhi Z. Liu, Jocelyn F. Chen, Meiling Zhang, Bryan T. Mott, Katherine Pohida,...

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Sometimes you’re the scooper, and sometimes you get scooped: How to turn both into something good

by Jin-Soo Kim, Jacob E. Corn Fast-moving, competitive fields often inadvertently duplicate research. In a research environment that values being first over being robust, this results in one manuscript “scooping”...

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In vitro–transcribed guide RNAs trigger an innate immune response via the RIG-I pathway

by Beeke Wienert, Jiyung Shin, Elena Zelin, Kathleen Pestal, Jacob E. Corn Clustered, regularly interspaced, short palindromic repeat (CRISPR)–CRISPR-associated 9 (Cas9) genome editing is revolutionizing fundamental research and has great...

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Wearable patch measures cortisol in sweat

Researchers from Stanford University have designed a wearable device that measures how much cortisol a person is producing through sweat, according to a press release from the university.“Our aim was...

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