immune response

Microbiome loss from antibiotic use affects response to flu vaccine

Every living person has trillions of microbes living in their digestive tract, and more than 400 species of bacteria in the gut, more than the number of cells in the...

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Study highlights the need to better understand immunity against mumps virus

Immunity against mumps virus appears insufficient in a fraction of college-aged people who were vaccinated in childhood, research from Emory Vaccine Center and the Centers for Disease Control and Prevention...

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Study gives insight into how immunotherapies may be delivered directly to brain tumors

A new study gives insight into how immunotherapies, treatments that help the body's immune system fight cancer, might one day be delivered directly to the brain in order to treat...

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Scientists reveal cancer cells' immune weak spot

Scientists have found a vulnerability in cancer cells that could make them more susceptible to being destroyed by the immune system, according to a new report in eLife. Source link

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Aging Narrows Gender Gap in Flu Vaccine Response

Here's some bad news for older women during flu season: Aging reduces the stronger immune response that women typically have to vaccination, a new study finds. Source link

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Advanced tools could lead to better cancer immunotherapy

In the journal Science Immunology, researchers from DTU Health Technology and Jacobs University in Bremen have just published their cutting-edge research demonstrating advancement in detection of a certain type of...

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Study reveals Lassa virus' soft spot

As this year's Lassa fever outbreak in Nigeria is finally ebbing, the total tally came to more than 600 infected people, one-quarter of them dead. Thousands more die each year,...

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Gut bacteria that prevents mice from becoming obese may also control weight in people

Researchers at University of Utah Health have identified a specific class of bacteria from the gut that prevents mice from becoming obese, suggesting these same microbes may similarly control weight...

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Novel sensor could accelerate diagnosis of sepsis

A novel sensor designed by MIT researchers could dramatically accelerate the process of diagnosing sepsis, a leading cause of death in U.S. hospitals that kills nearly 250,000 patients annually. Source...

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Study identifies genomic differences that impact response to Cryptococcus infection

Cryptococcus neoformans is a fungal pathogen that infects people with weakened immune systems, particularly those with advanced HIV/AIDS. New University of Minnesota Medical Research could mean a better understanding of...

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Gut microbiota protects from viral-induced neurologic damage, study finds

Gut microbes produce compounds that prime immune cells to destroy harmful viruses in the brain and nervous system, according to a mouse study published today in eLife. Source link

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Researchers find mechanism behind susceptibility to viral infections

A team of researchers from the SingHealth Duke-NUS Academic Medicine Centre's Viral Research and Experimental Medicine Centre found that immune cells undergoing stress and an altered metabolism are the reasons...

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New method spots rare immune cells reactive against cancer

Researchers from the Garvan Institute of Medical Research have developed a new method to spot rare immune cells that are reactive against cancer cells, from within a patient's own immune...

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Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts

by Karin Schaeuble, Hélène Cannelle, Stéphanie Favre, Hsin-Ying Huang, Susanne G. Oberle, Daniel E. Speiser, Dietmar Zehn, Sanjiv A. Luther Lymphoid T-zone fibroblastic reticular cells (FRCs) actively promote T-cell trafficking,...

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Special blood test may predict relapse risk for breast cancer patients

A special blood test may one day predict if a newly diagnosed breast cancer patient will likely relapse years later, a City of Hope study suggests. Source link

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New biomaterial could encapsulate and protect implanted insulin-producing cells

Transplanting insulin-producing pancreatic cells into people with type 1 diabetes has emerged as a ground-breaking treatment for millions of patients over the past few decades. Source link

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Comprehensive gene activity database could significantly reduce animal use

A comprehensive database of gene activity in mice across ten disease models, which could significantly reduce animal use worldwide, has been developed by scientists at the Francis Crick Institute, which...

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Study reveals genetic signature of failed immune response to cancer

Our immune system is programmed to destroy cancer cells. Sometimes it has trouble slowing disease progression because it doesn't act quickly or strongly enough. Source link

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Star nanoparticles delivering HIV-1 peptide minimal immunogens elicit near-native envelope antibody responses in nonhuman primates

by Joseph R. Francica, Richard Laga, Geoffrey M. Lynn, Gabriela Mužíková, Ladislav Androvič, Baptiste Aussedat, William E. Walkowicz, Kartika Padhan, Ramiro Andrei Ramirez-Valdez, Robert Parks, Stephen D. Schmidt, Barbara J....

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Detecting T cell receptors involved in immune responses from single repertoire snapshots

by Mikhail V. Pogorelyy, Anastasia A. Minervina, Mikhail Shugay, Dmitriy M. Chudakov, Yuri B. Lebedev, Thierry Mora, Aleksandra M. Walczak Hypervariable T cell receptors (TCRs) play a key role in...

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