immune response
- February 18, 2019
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- Tags: Cas9correctCRISPRdiseaseDNADuchenne Muscular DystrophydystrophinExonsGeneGeneticGenomeGenome Editingimmune responseImmune SystemmedicinemuscleMuscular DystrophyMutationNewbornproteinresearchSafelySingleStablytreatmentWheelchair
[ad_1] Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease -- Duchenne muscular dystrophy (DMD)...
Read more- February 15, 2019
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- Tags: cancercastrationresistantCellCheckpointchemotherapyClinical TrialcoldcombinationCTLA-4drugsHormonal Therapyimmuneimmune responseImmune SystemimmunologyimmunotherapyinhibitorsmedicinemetastaticOncologypHprostateprostate cancerresearchRespondsTumor
[ad_1] Some patients with metastatic prostate cancer respond to a combination of immune checkpoint inhibitors after hormonal therapy and chemotherapy have failed, according to early results from a clinical trial...
Read more- February 5, 2019
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- Tags: AntigenBarrelbloodcancerCelldrugsGeneGeneticHuman Leukocyte Antigenimmuneimmune responseImmune SysteminflammationkidneyKidney TransplantLeukocytemedicinemoleculeOrgansPerforinpowerfulProtectrejectionresearchsilencesTransplanttransplantedTumor
[ad_1] A powerful immune molecule helps protect transplanted organs from rejection by putting a silencer on two other immune molecules that converge to take a direct shot at the organ,...
Read more- January 31, 2019
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- Tags: bloodblood vesselsbrainDamagediabetesEnzymeexploreglaucomaimmune responseinflammationliverMacrophagesNerveneuronsretinalScientiststargetstreatmentVision Loss
[ad_1] Scientists at the Medical College of Georgia at Augusta University are looking at new treatment targets for the retinal damage that often accompanies diseases like diabetes, glaucoma and hypertension....
Read more- January 28, 2019
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- Tags: AllergybloodchildrenChildren039sCincinnatiClinicalClinical TrialEbolaEbola VirusHospitalimmune responseInfectious DiseasesLaboratoryNIAIDfundedpublic healthresearchtrialUnderwayvaccinevaccinesvirusViruses
[ad_1] A Phase 1 clinical trial of investigational vaccines intended to protect against Zaire ebolavirus (Ebola) is underway at Cincinnati Children's Hospital Medical Center in the United States. The study...
Read more- January 24, 2019
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- Tags: AllergyBeginsClinicalClinical TestingClinical Trialelectronexperimentalimmune responseInfectious DiseasesmedicinepHresearchtemperaturestableTestingtuberculosisvaccine
[ad_1] Vaccinations have begun in a Phase 1 human clinical trial testing a freeze-dried, temperature-stable formulation of an experimental tuberculosis vaccine candidate. Source link [ad_2]
Read more- January 12, 2019
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- Tags: AntibodiescancerCellCTLA-4drugsgenesidentifiedimmune responseimmunologyimmunotherapyLightMacrophagesMalignantmelanomaOncologyPancreaticPancreatic CancerpHPotentialresearchtargetTumor
[ad_1] Researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety...
Read more- January 11, 2019
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- Tags: actinCellcytoskeletonFindsfunctionHIVHospitalimmune responseImmune SystemimmunologyMedical SchoolmedicineproteinresearchSlowsspecificSpreadstudyviralvirusViruses
[ad_1] A study from a Massachusetts General Hospital research team has identified the specific function of a protein found in HIV and related viruses that appears to slow down viral...
Read more- January 11, 2019
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- Tags: Appearanceatherosclerosisbloodcardiovascular diseaseCellsExpressionimmune responseInverselymoleculepredictsresearchstrokesubclinical
[ad_1] Earlier detection of cardiovascular disease is a step closer thanks to the findings of a research team at the Centro Nacional de Investigaciones Cardiovasculares led by Francisco Sánchez-Madrid and...
Read more- December 15, 2018
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- Tags: approachCell DeathCell-mediated immunityimmune responseIntegrativeltigtPseudomonasnetworkcentricPathwaysplantProtein kinase signaling cascadeProtein kinasesPseudomonas syringaeResistanceRevealssignalingSignaling networksSusceptibilitysyringaeltigtTomatoes
[ad_1] by Elizabeth K. Brauer, George V. Popescu, Dharmendra K. Singh, Mauricio Calviño, Kamala Gupta, Bhaskar Gupta, Suma Chakravarthy, Sorina C. Popescu Plant protein kinases form redundant signaling pathways to...
Read more- September 2, 2018
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- Tags: AH3N2AntibodiesAntibodyAntibody responseB cellsdynamicsimmune responseImmunityinfluenzaMarkov modelsSerologytimescales
by Adam J. Kucharski, Justin Lessler, Derek A. T. Cummings, Steven Riley Human immunity influences the evolution and impact of influenza strains. Because individuals are infected with multiple influenza strains...
Read more- August 22, 2018
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- Tags: AH3N2AntibodiesAntibodyAntibody responseB cellsdynamicsimmune responseImmunityinfluenzaMarkov modelsSerologytimescales
by Adam J. Kucharski, Justin Lessler, Derek A. T. Cummings, Steven Riley Human immunity influences the evolution and impact of influenza strains. Because individuals are infected with multiple influenza strains...
Read more- August 7, 2018
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- Tags: cancer treatmentdemethylaseshistoneHistonesimmuneimmune responseInterferonsKDM5repressRESPONSEReverse transcriptionSmall interfering RNAsSTINGSuppressionT CellsVaccinia virus
by Lizhen Wu, Jian Cao, Wesley L. Cai, Sabine M. Lang, John R. Horton, Daniel J. Jansen, Zongzhi Z. Liu, Jocelyn F. Chen, Meiling Zhang, Bryan T. Mott, Katherine Pohida,...
Read more- July 25, 2018
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- Tags: AirportsComplement systemGenomicsGoodimmune responseMaizePlant genomicsReproducibilityscience policyscoopedscooperturnYoure
by Jin-Soo Kim, Jacob E. Corn Fast-moving, competitive fields often inadvertently duplicate research. In a research environment that values being first over being robust, this results in one manuscript “scooping”...
Read more- July 25, 2018
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- Tags: Guideimmuneimmune responseinnateInterferonspathwayPhosphatasesPolymerase chain reactionRESPONSERibonucleoproteinsRIGIRNA extractionRNA synthesisRNAsTransfectionTriggervitrotranscribed
by Beeke Wienert, Jiyung Shin, Elena Zelin, Kathleen Pestal, Jacob E. Corn Clustered, regularly interspaced, short palindromic repeat (CRISPR)–CRISPR-associated 9 (Cas9) genome editing is revolutionizing fundamental research and has great...
Read more- July 21, 2018
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- Tags: ” OnurParlaka person’s cortisol level may already be different from what it was at the time the test was takenaccording to a press release from the university. “Our aim was to develop a device that can give us more information about our health status than a single biomarker doesand a device that is potentially able to tell us how our metabolic and immune systems are affected by [our physiological] conditionscontribute to the development of chronic diseases.” Because current methods for testing cortisol levels require waiting several days for lab resultsimmune responsememory and [that] canMetabolismof the department of materials science and engineering and post-doctoral scholar at the Salleo Research Group at Stanford Universityover timePhDResearchers from Stanford University have designed a wearable device that measures how much cortisol a person is producing through sweatsince it [is] well documented that cortisol is the hormone that affects blood pressuretold Endocrine Today. “This curiosity brought us to [start] work on a cortisol sensor
Researchers from Stanford University have designed a wearable device that measures how much cortisol a person is producing through sweat, according to a press release from the university.“Our aim was...
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