hypercholesterolemia

Longitudinal low density lipoprotein cholesterol goal achievement and cardiovascular outcomes among adult patients with familial hypercholesterolemia: The CASCADE FH registry.

Related Articles Longitudinal low density lipoprotein cholesterol goal achievement and cardiovascular outcomes among adult patients with familial hypercholesterolemia: The CASCADE FH registry. Atherosclerosis. 2019 Aug 19;289:85-93 Authors: Duell PB, Gidding...

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Cholesterol lowering attenuates pressure overload-induced heart failure in mice with mild hypercholesterolemia.

Related Articles Cholesterol lowering attenuates pressure overload-induced heart failure in mice with mild hypercholesterolemia. Aging (Albany NY). 2019 Sep 04;11: Authors: Muthuramu I, Mishra M, Aboumsallem JP, Postnov A, Gheysens...

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Polygenic Risk Scores in Familial Hypercholesterolemia

Polygenic Risk Scores in Familial Hypercholesterolemia Source link

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Risk of Premature Atherosclerotic Disease in Patients With Monogenic Versus Polygenic Familial Hypercholesterolemia

AbstractBackground A pathogenic variant in LDLR, APOB, or PCSK9 can be identified in 30% to 80% of patients with clinically-diagnosed familial hypercholesterolemia (FH). Alternatively, ~20% of clinical FH is thought...

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'Double Whammy': Where do PCSK9 Inhibitors Fit for Diabetes/ACS?

Patients with diabetes as well as ACS and uncontrolled high cholesterol have a "double whammy" that makes them candidates for PCSK9 inhibitors to prevent CV events, says expert. Medscape Medical...

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A bacterium may limit cardiovascular risks of 1 in 2 people, study shows

In 2007, Patrice Cani (FNRS-WELBIO researcher) and his team at the Louvain Drug Research Institute of University of Louvain, in close collaboration with Willem de Vos, professor at UWageningen, discovered...

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The Impact of the International Cooperation On Familial Hypercholesterolemia Screening and Treatment: Results from the ScreenPro FH Project.

The Impact of the International Cooperation On Familial Hypercholesterolemia Screening and Treatment: Results from the ScreenPro FH Project. Curr Atheroscler Rep. 2019 Jun 22;21(9):36 Authors: Ceska R, Latkovskis G, Ezhov...

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Hypercholesterolemia Among Premature Infarcts: Time to Start the Clock of Familial Hypercholesterolemia Assessment

[ad_1] Hypercholesterolemia Among Premature Infarcts: Time to Start the Clock of Familial Hypercholesterolemia Assessment Source link [ad_2]

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Familial Hypercholesterolemia Among Young Adults With Myocardial Infarction

[ad_1] AbstractBackground There are limited data on the prevalence and treatment of familial hypercholesterolemia (FH) among U.S. adults who experience a myocardial infarction (MI) at a young age. Objectives This...

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Machine learning IDs risk for familial hypercholesterolemia

[ad_1] (HealthDay)—A machine learning classifier can effectively identify patients at risk for familial hypercholesterolemia (FH), according to a study published online April 11 in npj Digital Medicine. Source link [ad_2]

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Success for new cholesterol-lowering drug

[ad_1] A new, oral drug that effectively lowers LDL or "bad" cholesterol, looks set for clinical approval. Source link [ad_2]

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Value of Measuring Lipoprotein(a) During Cascade Testing for Familial Hypercholesterolemia

[ad_1] AbstractBackground Familial hypercholesterolemia (FH) and elevated lipoprotein(a) [Lp(a)] are inherited disorders associated with premature atherosclerotic cardiovascular disease (ASCVD). Cascade testing is recommended for FH, but there are no similar recommendations...

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Lipoprotein(a) as Risk Factor in Heterozygous Familial Hypercholesterolemia

[ad_1] Researchers examined whether lipoprotein(a) cholesterol life-years can effectively measure cumulative risk for atherosclerotic cardiovascular disease and questioned whether this metric may apply to the incidence of aortic valve calcification....

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Effects of Hypercholesterolemia and Statin Exposure on Survival in a Large National Cohort of Patients With Cirrhosis

[ad_1] Concerns related to hepatotoxicity frequently lead to discontinuation or non-initiation of HMG-coA reductase therapy in patients with cirrhosis despite data supporting statin use. We aimed to investigate the independent...

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Cardiovascular Disease Risk Factors in Heterozygous Familial Hypercholesterolemia

[ad_1] Smoking, hypertension, and diabetes contributed to more than a quarter of excess CVD risk in individuals with heterozygous familiar hypercholesterolemia. Source link [ad_2]

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Simvastatin Improves Inflammation, Platelet Activation Markers in Primary Hypercholesterolemia

[ad_1] In patients with primary hypercholesterolemia, short-term treatment with simvastatin improved the lipid profile and exerted a beneficial effect on a wide range of proatherogenic and prothrombotic parameters. Source link...

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Lifting weights for less than an hour a week may reduce cardiovascular disease risk

[ad_1] Lifting weights for less than an hour a week may reduce your risk for a heart attack or stroke by 40 to 70 percent, according to a new Iowa...

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Long-Term Evolocumab Safe and Effective for Treating Hypercholesterolemia

[ad_1] Evolocumab consistently reduced LDL-C with no increase in adverse events over a 5-year study period. Source link [ad_2]

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FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

[ad_1] Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved LORBRENA, a third-generation anaplastic lymphoma kinase tyrosine kinase inhibitor for patients with ALK-positive metastatic non-small cell...

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Genetic testing recommended for familial hypercholesterolemia

(HealthDay)—Genetic testing should become the standard of care for patients with definite or probable familial hypercholesterolemia (FH), according to a statement published in the Aug. 7 issue of the Journal...

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