Tag : Glutathione

Dermatology

Targeting PHGDH Upregulation Reduces Glutathione Levels and Resensitizes Resistant NRAS-Mutant Melanoma to MAPK Kinase Inhibition

Newsemia
Melanomas frequently harbor activating NRAS mutations leading to activation of MAPK kinase (MEK) and extracellular signal–regulated kinase 1/2 signaling; however, the clinical efficacy of inhibitors...
Cardiology

Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1.

Newsemia
Related Articles Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1. J Biol Chem. 2020...
Biology

Metabolic excretion associated with nutrient–growth dysregulation promotes the rapid evolution of an overt metabolic defect

Newsemia
by Robin Green, Sonal, Lin Wang, Samuel F. M. Hart, Wenyun Lu, David Skelding, Justin C. Burton, Hanbing Mi, Aric Capel, Hung Alex Chen, Aaron...
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Glutathione release from astrocytes; Characterization and implications for neurodegeneration

Newsemia
Stone, Rebecca; (2002) Glutathione release from astrocytes; Characterization and implications for neurodegeneration. Doctoral thesis (Ph.D), UCL (University College London). Green open access Source link...
Latest News

Nitric oxide and glutathione as modulators of thalamic sensory neurotransmission in the rat

Newsemia
Shaw, Philip John; (1998) Nitric oxide and glutathione as modulators of thalamic sensory neurotransmission in the rat. Masters thesis (M.Phil), UCL (University College London). Green...
Pediatrics

An Existing Drug May Have Therapeutic Potential in Mitochondrial Disease

Newsemia
New preclinical findings from extensive cell and animal studies suggest that cysteamine bitartrate, a drug already used for a rare kidney disease, could benefit patients...
Pharma / Biotech

Glutathione S-transferase M1 and T1 null allele frequencies among Indonesian ethnics toward improved disease risk assessment.

Newsemia
Related Articles Glutathione S-transferase M1 and T1 null allele frequencies among Indonesian ethnics toward improved disease risk assessment. Environ Toxicol Pharmacol. 2018 Nov 02;65:14-17 Authors:...
Cardiology

LC-MS analysis of key components of the glutathione cycle in tissues and body fluids from mice with myocardial infarction.

Newsemia
Related Articles LC-MS analysis of key components of the glutathione cycle in tissues and body fluids from mice with myocardial infarction. J Pharm Biomed Anal....
Pharma / Biotech

Activated charcoal significantly improved the reliability of methods for quantitative analysis of endogenous substances in biological specimens: Glutathione and cysteine as cases.

Newsemia
Related Articles Activated charcoal significantly improved the reliability of methods for quantitative analysis of endogenous substances in biological specimens: Glutathione and cysteine as cases. J...

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