Tag: Genomic libraries

Biology

Precise genomic mapping of 5-hydroxymethylcytosine via covalent tether-directed sequencing

Newsemia
by Povilas Gibas, Milda Narmontė, Zdislav Staševskij, Juozas Gordevičius, Saulius Klimašauskas, Edita Kriukienė 5-hydroxymethylcytosine (5hmC) is the most prevalent intermediate on the oxidative DNA demethylation...
Biology

Transcription-induced formation of extrachromosomal DNA during yeast ageing

Newsemia
by Ryan M. Hull, Michelle King, Grazia Pizza, Felix Krueger, Xabier Vergara, Jonathan Houseley Extrachromosomal circular DNA (eccDNA) facilitates adaptive evolution by allowing rapid and...
Biology

Dynamic evolution in the key honey bee pathogen deformed wing virus: Novel insights into virulence and competition using reverse genetics

Newsemia
by Eugene V. Ryabov, Anna K. Childers, Dawn Lopez, Kyle Grubbs, Francisco Posada-Florez, Daniel Weaver, William Girten, Dennis vanEngelsdorp, Yanping Chen, Jay D. Evans The...
Biology

Rapid antigen diversification through mitotic recombination in the human malaria parasite <i>Plasmodium falciparum</i>

Newsemia
by Xu Zhang, Noah Alexander, Irina Leonardi, Christopher Mason, Laura A. Kirkman, Kirk W. Deitsch Malaria parasites possess the remarkable ability to maintain chronic infections...
Biology

De novo assembly of a young <i>Drosophila</i> Y chromosome using single-molecule sequencing and chromatin conformation capture

Newsemia
by Shivani Mahajan, Kevin H.-C. Wei, Matthew J. Nalley, Lauren Gibilisco, Doris Bachtrog While short-read sequencing technology has resulted in a sharp increase in the...

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