Tag : Genomewide

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Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases

Newsemia
Traylor, M; Knevel, R; Cui, J; Taylor, J; Harm-Jan, W; Conaghan, PG; Cope, AP; … Scott, IC; + view all Traylor, M; Knevel, R; Cui,...
AI/ML

Genome-wide prediction and prioritization of human aging genes by data fusion: a machine learning approach.

Newsemia
Related Articles Genome-wide prediction and prioritization of human aging genes by data fusion: a machine learning approach. BMC Genomics. 2019 Nov 09;20(1):832 Authors: Arabfard M,...
Biology

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

Newsemia
by Cynthia J. Sakofsky, Natalie Saini, Leszek J. Klimczak, Kin Chan, Ewa P. Malc, Piotr A. Mieczkowski, Adam B. Burkholder, David Fargo, Dmitry A. Gordenin...
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Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

Newsemia
Ji, S-G; Juran, BD; Mucha, S; Folseraas, T; Jostins, L; Melum, E; Kumasaka, N; … Anderson, CA; + view all Ji, S-G; Juran, BD; Mucha,...
Biology

Genome-Wide CRISPR Screen Reveals Autophagy Disruption as the Convergence Mechanism That Regulates the NRF2 Transcription Factor [Research Article]

Newsemia
The nuclear factor (erythroid 2)-like 2 (NRF2 or NFE2L2) transcription factor regulates the expression of many genes that are critical in maintaining cellular homeostasis. Its...
Biology

Genome-wide sexually antagonistic variants reveal long-standing constraints on sexual dimorphism in fruit flies

Newsemia
by Filip Ruzicka, Mark S. Hill, Tanya M. Pennell, Ilona Flis, Fiona C. Ingleby, Richard Mott, Kevin Fowler, Edward H. Morrow, Max Reuter The evolution...

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