Genome

Study shows how cervicovaginal microbiome can elicit resistance to chlamydia

The vaginal microbiome is believed to protect women against Chlamydia trachomatis, the etiological agent of the most prevalent sexually transmitted infections in developed countries. Source link

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UCLA-led researchers identify 69 genes that increase risk for autism spectrum disorder

A UCLA-led research team has identified dozens of genes, including 16 new genes, that increase the risk of autism spectrum disorder. Source link

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New technique finds medically and ecologically relevant bacteria groups

Identifying species among plants and animals has been a full-time occupation for some biologists, but the task is even more daunting for the myriad microbes that inhabit the planet. Source...

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Genome editing strategy opens new perspectives in the treatment of cystic fibrosis

The approach adopted by the team of the University of Trento, led by Anna Cereseto, opens new perspectives in the treatment of cystic fibrosis, a genetic disease for which no...

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Discovery of protective protein could open door to better treatment of fast-growing cancer cells

The discovery that an essential protein plays a protective role during cell division, could open the door to better targeted treatment of fast-growing cancer cells. Source link

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Study reveals the complexities of viral evolution

Comparing a living cell to a virus is a bit like comparing the Sistine Chapel to a backyard dog house. Lacking the intricate machinery of living cells, viruses represent biology...

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Study identifies multiple regions in the genome linked to risk of re-experiencing PTSD

A study based on the Million Veteran Program of the U.S. Department of Veterans Affairs has identified multiple locations in the human genome related to the risk of re-experiencing traumatic...

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Fitness Landscape of the Fission Yeast Genome

AbstractThe relationship between DNA sequence, biochemical function, and molecular evolution is relatively well-described for protein-coding regions of genomes, but far less clear in noncoding regions, particularly, in eukaryote genomes. In...

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New gene-editing study finds protective genes against Zika virus

Tel Aviv scientists have discovered certain genes that protect the host organism against attack by Zika virus, raising hopes of an eventual vaccine or cure for this dreaded viral disease....

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New CRISPR platform expands the reach of RNA editing to new targets

CRISPR-based tools have revolutionized our ability to target disease-linked genetic mutations. CRISPR technology comprises a growing family of tools that can manipulate genes and their expression, including by targeting DNA...

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Sequencing data could be used to prevent lyme disease

Researchers have successfully sequenced the genome of the animal that could carry the bacteria causing Lyme disease. Source link

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Mouse, not just tick: New genome heralds change in Lyme disease fight

As Lyme disease increases, researchers have taken a significant step toward finding new ways to prevent its transmission. The experts, who include a pioneer in Lyme disease discovery, have sequenced...

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Common feature that makes cancer cells appear bloated could be their potential weak spot

In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report they have found a potential weak spot among cancer cells that have extra...

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Scientists confirm HIV theory by sequencing 53-year old tissue

Researchers have extracted a near-complete HIV-1 genome from the lymph node tissue of a man who has been embedded in wax since 1966. Source link

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Study provides new insight into how changes in DNA methylation contribute to diseases

More than half of our genome consists of transposons, DNA sequences that are reminiscent of ancient, extinct viruses. Source link

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Large-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients

Large-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients Source link

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Abcam Acquire Off-The-Shelf Diploid Library of Over 2,800 Knockout Cell Lines

Abcam has announced the acquisition of the entire KO live cell line and lysates portfolio of EdiGene. The new range will be available later this year. Source link

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Paternally Acting Canonical RNA-Directed DNA Methylation Pathway Genes Sensitize Arabidopsis Endosperm to Paternal Genome Dosage

Seed development is sensitive to parental dosage, with excess maternal or paternal genomes creating reciprocal phenotypes. Paternal genomic excess frequently results in extensive endosperm proliferation without cellularization and seed abortion....

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Genetic heterogeneity of mitochondrial genome in thiamine deficient Leigh syndrome patients

In our previously published study, we cared for 165 thiamine deficient Leigh syndrome (LS) patients who presented in acute life threatening conditions with severe neurological abnormalities. However the molecular basis...

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Study provides new insight into the heritability of coronary artery disease

A collaboration involving the Icahn School of Medicine at Mount Sinai, the German Heart Center Munich, AstraZeneca, and Karolinska Institutet in Sweden has demonstrated that more than 30 percent of...

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