Discovering a molecule that could interfere with SARS-CoV-2 replication
In this interview, News-Medical speaks to Stepan Nersisyan about his discovery of a molecule that could replicate SARS-CoV-2. Source link...
Tag : gene expression
Two unequally redundant "helper" immune receptor families mediate <i>Arabidopsis thaliana</i> intracellular "sensor" immune receptor functions
by Svenja C. Saile, Pierre Jacob, Baptiste Castel, Lance M. Jubic, Isai Salas-Gonzalez, Marcel Bäcker, Jonathan D. G. Jones, Jeffery L. Dangl, Farid El Kasmi...
In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age
by Nicole A. P. Lieberman, Vikas Peddu, Hong Xie, Lasata Shrestha, Meei-Li Huang, Megan C. Mears, Maria N. Cajimat, Dennis A. Bente, Pei-Yong Shi, Francesca...
Novel RNA vaccine from Arcturus Therapeutics protects mice against SARS-CoV-2
A new study published on the preprint server bioRxiv in September 2020 reports a novel RNA vaccine platform that shows robust protection against severe acute...
Advances in Virus Epigenetics
Growing evidence shows viruses exploit epigenetic processes to control their life cycles but epigentic regulation of viral infections is not fully understood. Source link...
Inhaled steroids reduce SARS-CoV-2-related genes in COPD
A new study published on the preprint server medRxiv* aims to explore the effects of treatment with ICS on the expression of specific genes related...
Experts caution against routine use of current GEP tests for melanoma patients
A consensus statement published today in JAMA Dermatology by an international group of melanoma researchers evaluates the use of prognostic genetic expression profile (GEP) testing...
HENA, heterogeneous network-based data set for Alzheimer's disease.
Related Articles HENA, heterogeneous network-based data set for Alzheimer’s disease. Sci Data. 2019 08 14;6(1):151 Authors: Sügis E, Dauvillier J, Leontjeva A, Adler P, Hindie...
Study indicates a potential link between Alzheimer's and common brain disorder
Alzheimer’s disease is one of the most common causes of dementia, and while most people might know someone who is affected by it, the genetic...
Adaptions to aging may be impacted by genetic background
How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist at the University of California,...
Enzyme could play key role in treating cancer, autoimmune diseases in the airway
Findings from a research study, led by scientists at Henry Ford, published in the latest issue of Nature Communications suggest an enzyme could play an...
USF Health researchers develop new reporter mouse strain for identifying P2X2-expressing cells
Despite frequent news announcing “medical breakthroughs,” advancements in biomedical and clinical science typically happen incrementally. Source link...
Heritable gene expression variability and stochasticity govern clonal heterogeneity in circadian period
by K. L. Nikhil, Sandra Korge, Achim Kramer A ubiquitous feature of the circadian clock across life forms is its organization as a network of...
McGill researchers discover bacterial organelles involved in gene expression
Researchers at McGill University have discovered bacterial organelles involved in gene expression, suggesting that bacteria may not be as simple as once thought. Source link...
Study identifies possible factors to predict severe toxicities in CAR T patients
Chimeric antigen receptor T-cell therapy (CAR T) has proved to be a valuable treatment option for patients with lymphoma who have failed other therapies. In...
The pregnant myometrium is epigenetically activated at contractility-driving gene loci prior to the onset of labor in mice
by Virlana M. Shchuka, Luis E. Abatti, Huayun Hou, Nawrah Khader, Anna Dorogin, Michael D. Wilson, Oksana Shynlova, Jennifer A. Mitchell During gestation, uterine smooth...
Researchers show how upregulation of a single gene by SARs-CoV-2 can trigger cytokine storm
The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs). Source link...
Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer
by María Gutiérrez-Salmerón, José Manuel García-Martínez, Javier Martínez-Useros, María Jesús Fernández-Aceñero, Benoit Viollet, Severine Olivier, Jagat Chauhan, Silvia R. Lucena, Antonio De la Vieja, Colin...
Creating the first 3D neural map of a heart
News-Medical spoke to Dr. Vadigepalli and Dr. Schwaber about their groundbreaking research in which they managed to map the neurons in the heart. Source link...
Texas A&M scientists develop 2D nanosheets to advance cancer treatment
Scientists in the Department of Biomedical Engineering at Texas A&M University are developing new ways to advance the field of regenerative medicine and cancer treatment....