Tag: gene expression

Biology

Photosensing and quorum sensing are integrated to control <i>Pseudomonas aeruginosa</i> collective behaviors

Newsemia
by Sampriti Mukherjee, Matthew Jemielita, Vasiliki Stergioula, Mikhail Tikhonov, Bonnie L. Bassler Bacteria convert changes in sensory inputs into alterations in gene expression, behavior, and...
Biology

Loss of adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22

Newsemia
by Yu Chen, Maud Vandereyken, Ian P. Newton, Ignacio Moraga, Inke S. Näthke, Mahima Swamy Interleukin-22 (IL-22) is a critical immune defence cytokine that maintains...
Biology

GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors

Newsemia
by Krishna Sriram, Kevin Moyung, Ross Corriden, Hannah Carter, Paul A. Insel G protein-coupled receptors (GPCRs) are the most widely targeted gene family for Food...
Gastroenterology

Discovery in C. difficile biology opens new window to developing treatments for dangerous infections

Newsemia
A process called sporulation that helps the dangerous bacterium Clostridium difficile (C. difficile) to survive inhospitable conditions and spread is regulated by epigenetics, factors that...
Biology

Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity

Newsemia
by Hugo G. Hilton, Nimrod D. Rubinstein, Peter Janki, Andrea T. Ireland, Nicholas Bernstein, Nicole L. Fong, Kevin M. Wright, Megan Smith, David Finkle, Baby...
Biology

Local vulnerability and global connectivity jointly shape neurodegenerative disease propagation

Newsemia
by Ying-Qiu Zheng, Yu Zhang, Yvonne Yau, Yahar Zeighami, Kevin Larcher, Bratislav Misic, Alain Dagher It is becoming increasingly clear that brain network organization shapes...
Latest News

Yale-led study provides roadmap to discover new treatment for idiopathic pulmonary fibrosis

Newsemia
A Yale-led collaborative study boosts scientific understanding of how the lung disease idiopathic pulmonary fibrosis (IPF) progresses, providing a roadmap for researchers to discover new...
Biology

Transcriptional regulatory divergence underpinning species-specific learned vocalization in songbirds

Newsemia
by Hongdi Wang, Azusa Sawai, Noriyuki Toji, Rintaro Sugioka, Yukino Shibata, Yuika Suzuki, Yu Ji, Shin Hayase, Satoru Akama, Jun Sese, Kazuhiro Wada Learning of...
Biology

Recurrent functional misinterpretation of RNA-seq data caused by sample-specific gene length bias

Newsemia
by Shir Mandelboum, Zohar Manber, Orna Elroy-Stein, Ran Elkon Data normalization is a critical step in RNA sequencing (RNA-seq) analysis, aiming to remove systematic effects...
Biology

The intragenus and interspecies quorum-sensing autoinducers exert distinct control over <i>Vibrio cholerae</i> biofilm formation and dispersal

Newsemia
by Andrew A. Bridges, Bonnie L. Bassler Vibrio cholerae possesses multiple quorum-sensing (QS) systems that control virulence and biofilm formation among other traits. At low...
Latest News

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

Newsemia
A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable...
Biology

Phase variation of a signal transduction system controls <i>Clostridioides difficile</i> colony morphology, motility, and virulence

Newsemia
by Elizabeth M. Garrett, Ognjen Sekulovic, Daniela Wetzel, Joshua B. Jones, Adrianne N. Edwards, Germán Vargas-Cuebas, Shonna M. McBride, Rita Tamayo Recent work has revealed...

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