Tag : folding

Biology

Genetically modified non-human primate fetuses as models to study the role of candidate genes for increasing size and folding of the human neocortex during development and evolution

Newsemia
By Michael Heide and Wieland B. Huttner   Introduction The neocortex is the seat of our higher cognitive abilities that distinguish us from other mammals...
Biology

Protein Melting Temperature Cannot Fully Assess Whether Protein Folding Free Energy Underlies the Universal Abundance–Evolutionary Rate Correlation Seen in Proteins

Newsemia
Abstract The protein misfolding avoidance hypothesis explains the universal negative correlation between protein abundance and sequence evolutionary rate across the proteome by identifying protein folding...
Biology

The noisy basis of morphogenesis: Mechanisms and mechanics of cell sheet folding inferred from developmental variability

Newsemia
by Pierre A. Haas, Stephanie S. M. H. Höhn, Aurelia R. Honerkamp-Smith, Julius B. Kirkegaard, Raymond E. Goldstein Variability is emerging as an integral part...

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