FirstLine

Last Patient Enrolled in the Phase 2 Trial with Transgene’s TG4010 + Nivolumab + Chemotherapy for the First-Line Treatment of Advanced Lung Cancer (NSCLC)

STRASBOURG, France--(BUSINESS WIRE)--lt;a href="https://twitter.com/hashtag/TG4010?src=hash" target="_blank"gt;#TG4010lt;/agt;--Regulatory News: Transgene (Paris:TNG), a biotech company that designs and develops virus-based immunotherapies for the treatment of solid tumors, today announces that the last patient has...

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Simplifying switch to second line ART: Predicted effect of defining failure of first-line efavirenz-based regimens in sub-Saharan Africa by a single viral load > 1000 copies/ml

[ad_1] Shroufi, A; Van Cutsem, G; Cambiano, V; Bansi-Matharu, L; Duncan, K; Murphy, RA; Maman, D; Shroufi, A; Van Cutsem, G; Cambiano, V; Bansi-Matharu, L; Duncan, K; Murphy, RA; Maman,...

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Very high pre-therapy viral load is a predictor of virological rebound in HIV-1-infected patients starting a modern first-line regimen

[ad_1] Armenia, D; Di Carlo, D; Cozzi-Lepri, A; Calcagno, A; Borghi, V; Gori, C; Bertoli, A; ... ICONA Foundation Study Group, ; + view all Armenia, D; Di Carlo, D;...

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FDA Approves Ivosidenib as First-Line Therapy for AML

The agency reviewed the application for ivosidenib using its Real-Time Oncology Review pilot program. Source link

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Keytruda Gains 2 New First-Line Indications: NSCLC and RCC

The FDA approved pembrolizumab (Keytruda, Merck) for the first-line treatment of patients with stage III/IV non-small cell lung cancer who are not candidates for surgery or definitive chemoradiation. The agency...

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New First-Line Treatment for Severe Malaria in U.S.

[ad_1] Title: New First-Line Treatment for Severe Malaria in U.S.Category: Health NewsCreated: 3/28/2019 12:00:00 AMLast Editorial Review: 3/29/2019 12:00:00 AM Source link [ad_2]

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Anakinra as First-line Monotherapy Wins in sJIA (CME/CE)

(MedPage Today) -- Study reports "highly efficacious strategy to induce and sustain inactive disease and to prevent disease- and glucocorticoid-related damage" Source link

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KEYTRUDA® (pembrolizumab) in Combination with Inlyta® (axitinib) Reduced Risk of Death by Nearly Half Compared to Sunitinib as First-Line Treatment for Advanced Renal Cell Carcinoma (RCC)

[ad_1] KENILWORTH, N.J.--(BUSINESS WIRE)--lt;a href="https://twitter.com/search?q=%24MRK&src=ctag" target="_blank"gt;$MRKlt;/agt; lt;a href="https://twitter.com/hashtag/Keytruda?src=hash" target="_blank"gt;#Keytrudalt;/agt;--KEYTRUDA in Combination with Inlyta Reduced Risk of Death by Nearly Half Compared to Sunitinib as First-Line Treatment for Advanced RCC Source...

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No Benefit With Ramucirumab in First-Line Gastric Cancer Tx (CME/CE)

[ad_1] (MedPage Today) -- Unlike phase II results, no benefit seen in progression-free or overall survival Source link [ad_1]

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FDA Approves Imbruvica With Gazyva for First-Line CLL Treatment

[ad_1] The FDA expanded the labeling for Imbruvicato include use with Gazyva in treatment-naive patients with chronic lymphocytic leukemia/small lymphocytic lymphoma.  Source link [ad_2]

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Treatment effects of the differential first-line antiretroviral regimens among HIV/HBV coinfected patients in southwest China: an observational study

[ad_1] Treatment effects of the differential first-line antiretroviral regimens among HIV/HBV coinfected patients in southwest China: an observational study Source link [ad_1]

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Tecentriq Combo Approved for First-Line Rx of Metastatic Nonsquamous NSCLC

[ad_1] The FDA approved atezolizumab (Tecentriq, Genentech) in combination with bevacizumab (Avastin, Genentech), paclitaxel and carboplatin for the first-line treatment of patients with metastatic nonsquamous, non-small cell lung cancer (NSCLC)...

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A two-microRNA-based signature predicts first-line chemotherapy outcomes in advanced colorectal cancer patients

[ad_1] A two-microRNA-based signature predicts first-line chemotherapy outcomes in advanced colorectal cancer patients Source link [ad_1]

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Prostate cancer detection using MRI now first-line investigation tool

[ad_1] Men with prostate cancers under the NHS would soon get non-invasive MRI scans for detections after a health body (National Institute for Health and Care Excellence or NICE) has...

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New first-line treatment for peripheral T-cell lymphoma approved by FDA

[ad_1] The U.S. Food and Drug Administration today expanded the approved use of Adcetris (brentuximab vedotin) injection in combination with chemotherapy for adult patients with certain types of peripheral T-cell...

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Predicted antiviral activity of tenofovir versus abacavir in combination with a cytosine analogue and the integrase inhibitor dolutegravir in HIV-1-infected South African patients initiating or failing first-line ART

[ad_1] Derache, A; Iwuji, CC; Danaviah, S; Giandhari, J; Marcelin, A-G; Calvez, V; de Oliveira, T; ... Gupta, RK; + view all Derache, A; Iwuji, CC; Danaviah, S; Giandhari, J;...

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Keytruda Approved as First-Line Rx for Metastatic Squamous NSCLC

[ad_1] The FDA expanded the indications for pembrolizumab (Keytruda, Merck) to include first-line treatment of metastatic squamous NSCLC in combination with carboplatin and either paclitaxel or nab-paclitaxel. Source link [ad_2]

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Takeda announces positive Phase 3 ALTA-1L data in first-line therapy for advanced ALK+ NSCLC

Takeda Pharmaceutical Company Limited today announced that intracranial efficacy data from the Phase 3 ALTA-1L (ALK in Lung Cancer Trial of BrigAtinib in 1st Line) trial showed improved intracranial progression-free...

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Samenvatting: Takeda komt met resulaten van fase 3 ALTA-1L Trial Intracranial Efficacy van ALUNBRIG® (brigatinib) Versus Crizotinib in First-Line Advanced ALK+ Non-Small Cell longkanker

CAMBRIDGE, Mass. & OSAKA, Japan--(BUSINESS WIRE)--– Bij patiënten met hersenmetastasen op de basislijn heeft ALUNBRIG het risico van progressie in de hersenen of de dood met 73 procent verminderd. –...

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Budesonide effective first-line treatment for lymphocytic colitis

Oral budesonide was safe and effective as a first-line treatment for lymphocytic colitis, according to research published in Gastroenterology.Stephen Miehlke, MD, of the Center for Digestive Diseases at Internal Medicine...

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