Tag: export

Biology

The Human DNA Mismatch Repair Protein MSH3 Contains Nuclear Localization and Export Signals That Enable Nuclear-Cytosolic Shuttling in Response to Inflammation [Research Article]

Newsemia
Inactivation of DNA mismatch repair propels colorectal cancer (CRC) tumorigenesis. CRCs exhibiting elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) show reduced nuclear MutS homolog...
Latest News

Genetron Health Receives FDA Emergency Use Authorization for SARS-CoV-2 RNA Test and Approval for Export by Chinese Authority

Newsemia
BEIJING–(BUSINESS WIRE)–Genetron Holdings Limited (“Genetron Health”), a China-based precision oncology company that covers full-cycle cancer care, announced that its independently developed detection kit for the...
Pediatrics

COVID-19 Update: India Lifts HCQ Export Ban; Testing a 'Massive Logistical Failure'; Baseball to Start in May?

Newsemia
<![CDATA[]]>(MedPage Today) — Note that some links may require registration or subscription. India agreed to lift an export ban on hydroxychloroquine (HCQ) after the Trump...
Biology

An F-Box Protein, Mdm30, Interacts with TREX Subunit Sub2 To Regulate Cellular Abundance Cotranscriptionally in Orchestrating mRNA Export Independently of Splicing and Mitochondrial Function [Research Article]

Newsemia
Although an F-box protein, Mdm30, is found to regulate ubiquitylation of the Sub2 component of TREX (transcription-export) complex for proteasomal degradation in stimulation of mRNA...

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