Tag: exit

Gastroenterology

The Transcription co-Repressors MTG8 and MTG16 Regulate Exit of Intestinal Stem Cells From Their Niche and Differentiation into Enterocyte vs Secretory Lineages

Newsemia
Notch signaling maintains intestinal stem cells (ISCs). When ISCs exit the niche, Notch signaling among early progenitor cells at position +4/5 regulates their specification toward...
Latest News

The Great Escape: how phosphatidylinositol 4-kinases and PI4P promote vesicle exit from the Golgi (and drive cancer)

Newsemia
Waugh, MG; (2019) The Great Escape: how phosphatidylinositol 4-kinases and PI4P promote vesicle exit from the Golgi (and drive cancer). Biochemical Journal , 476 (16)...
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Phosphoproteome dynamics during mitotic exit in budding yeast

Newsemia
Touati, SA; Kataria, M; Jones, AW; Snijders, AP; Uhlmann, F; (2018) Phosphoproteome dynamics during mitotic exit in budding yeast. EMBO Journal , 37 (10) ,...
Biology

Changes in chromatin accessibility ensure robust cell cycle exit in terminally differentiated cells

Newsemia
by Yiqin Ma, Daniel J. McKay, Laura Buttitta During terminal differentiation, most cells exit the cell cycle and enter into a prolonged or permanent G0...
Latest News

CORRECTING and REPLACING Civilization Ventures Announces Portfolio Exit with Acquisition of Singular Bio by Invitae (NYSE: NVTA)

Newsemia
SAN FRANCISCO–(BUSINESS WIRE)–<a href="https://twitter.com/search?q=%24NVTA&src=ctag" target="_blank">$NVTA</a> <a href="https://twitter.com/hashtag/diagnostics?src=hash" target="_blank">#diagnostics</a>–In the headline, and in the first sentence of the release, “(NASDAQ: NVTA)” should instead read “(NYSE: NVTA)”...
Biology

Uncoupling the Senescence-Associated Secretory Phenotype from Cell Cycle Exit via Interleukin-1 Inactivation Unveils Its Protumorigenic Role [Research Article]

Newsemia
Cellular senescence has emerged as a potent tumor suppressor mechanism in numerous human neoplasias. Senescent cells secrete a distinct set of factors, collectively termed the...
Biology

Surf4 (Erv29p) binds amino-terminal tripeptide motifs of soluble cargo proteins with different affinities, enabling prioritization of their exit from the endoplasmic reticulum

Newsemia
by Ying Yin, Mekka R. Garcia, Alexander J. Novak, Allison M. Saunders, Raira S. Ank, Anna S. Nam, Larry W. Fisher Some secreted proteins that...

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