Tag : epithelial

Pharma / Biotech

Phase I study of metformin in combination with carboplatin/paclitaxel chemotherapy in patients with advanced epithelial ovarian cancer.

Newsemia
Related Articles Phase I study of metformin in combination with carboplatin/paclitaxel chemotherapy in patients with advanced epithelial ovarian cancer. Invest New Drugs. 2020 Mar 07;:...
Gastroenterology

P150 ENHANCING EPITHELIAL BARRIER FUNCTION WITH NOVEL E-CADHERIN ACTIVATING MONOCLONAL ANTIBODIES REDUCES INFLAMMATORY BOWEL DISEASE PROGRESSION IN MOUSE MODELS

Newsemia
Deficits in gastrointestinal (GI) epithelial barrier function play important roles in the pathogenesis of Inflammatory Bowel Disease (IBD). The CDH1 gene encoding E-cadherin, a key...
Gastroenterology

7 LACTOBACILLUS REUTERI SUPPRESSES PRO-INFLAMMATORY DRIVEN REACTIVE OXYGEN SPECIES IN VITRO IN HUMAN INTESTINAL EPITHELIAL CELLS AND IN VIVO IN A TNBS COLITIS MOUSE MODEL

Newsemia
Reactive oxygen species (ROS) play a role in maintaining intestinal epithelial homeostasis and are normally kept at low levels via antioxidant compounds. Dysregulation of ROS...
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Investigating Human Oesophageal Epithelial Stem-Progenitor Cells and their Ability to Reconstruct a Functional Epithelium within a Tissue Engineered Oesophagus

Newsemia
Phylactopoulos, Demetra-Ellie; (2019) Investigating Human Oesophageal Epithelial Stem-Progenitor Cells and their Ability to Reconstruct a Functional Epithelium within a Tissue Engineered Oesophagus. Doctoral thesis (Ph.D),...
Gastroenterology

Autophagy of Intestinal Epithelial Cells Inhibits Colorectal Carcinogenesis Induced by Colibactin-producing Escherichia coli in ApcMin/+ Mice

Newsemia
Infection with colibactin-producing Escherichia coli promotes autophagy of intestinal epithelial cells, which is required to prevent the carcinogenic effects of these bacteria. Source link...
Biology

Malpighian tubules of caterpillars: blending RNAseq and physiology to reveal regional functional diversity and novel epithelial ion transport control mechanisms [RESEARCH ARTICLE]

Newsemia
Dennis Kolosov and Michael J. O’Donnell The Malpighian tubules (MTs) and hindgut constitute the functional kidney of insects. MTs are outpouchings of the gut and...
Biology

Loss of adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22

Newsemia
by Yu Chen, Maud Vandereyken, Ian P. Newton, Ignacio Moraga, Inke S. Näthke, Mahima Swamy Interleukin-22 (IL-22) is a critical immune defence cytokine that maintains...

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