Tag : Endoplasmic reticulum

Biology

SorCS1-mediated sorting in dendrites maintains neurexin axonal surface polarization required for synaptic function

Newsemia
by Luís F. Ribeiro, Ben Verpoort, Julie Nys, Kristel M. Vennekens, Keimpe D. Wierda, Joris de Wit The pre- and postsynaptic membranes comprising the synaptic...
Biology

Reticulon and CLIMP-63 regulate nanodomain organization of peripheral ER tubules

Newsemia
by Guang Gao, Chengjia Zhu, Emma Liu, Ivan R. Nabi The endoplasmic reticulum (ER) is an expansive, membrane-enclosed organelle composed of smooth peripheral tubules and...
Biology

Fast calcium transients in dendritic spines driven by extreme statistics

Newsemia
by Kanishka Basnayake, David Mazaud, Alexis Bemelmans, Nathalie Rouach, Eduard Korkotian, David Holcman Fast calcium transients (<10 ms) remain difficult to analyse in cellular microdomains,...
Biology

HSP-4/BiP expression in secretory cells is regulated by a developmental program and not by the unfolded protein response

Newsemia
by Ji Zha, Mingjie Ying, Jasmine Alexander-Floyd, Tali Gidalevitz Differentiation of secretory cells leads to sharp increases in protein synthesis, challenging endoplasmic reticulum (ER) proteostasis....
Biology

Identification of molecular determinants that govern distinct STIM2 activation dynamics

Newsemia
by Sisi Zheng, Guolin Ma, Lian He, Tian Zhang, Jia Li, Xiaoman Yuan, Nhung T. Nguyen, Yun Huang, Xiaoyan Zhang, Ping Gao, Robert Nwokonko, Donald...
Biology

Morphology of mitochondria in spatially restricted axons revealed by cryo-electron tomography

Newsemia
by Tara D. Fischer, Pramod K. Dash, Jun Liu, M. Neal Waxham Neurons project axons to local and distal sites and can display heterogeneous morphologies...
Biology

Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites

Newsemia
by Michael J. Boucher, Sreejoyee Ghosh, Lichao Zhang, Avantika Lal, Se Won Jang, An Ju, Shuying Zhang, Xinzi Wang, Stuart A. Ralph, James Zou, Joshua...
Biology

Surf4 (Erv29p) binds amino-terminal tripeptide motifs of soluble cargo proteins with different affinities, enabling prioritization of their exit from the endoplasmic reticulum

Newsemia
by Ying Yin, Mekka R. Garcia, Alexander J. Novak, Allison M. Saunders, Raira S. Ank, Anna S. Nam, Larry W. Fisher Some secreted proteins that...

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