Tag : endogenous

Pharma / Biotech

Analysis of endogenous epinephrine and norepinephrine enantiomers in rat plasma and application to a stereoselective pharmacokinetics.

Newsemia
Related Articles Analysis of endogenous epinephrine and norepinephrine enantiomers in rat plasma and application to a stereoselective pharmacokinetics. J Pharm Biomed Anal. 2019 Sep 06;177:112859...
Biology

AMPK regulates germline stem cell quiescence and integrity through an endogenous small RNA pathway

Newsemia
by Pratik Kadekar, Richard Roy During suboptimal growth conditions, Caenorhabditis elegans larvae undergo a global developmental arrest called “dauer.” During this stage, the germline stem...
Biology

Cellular labeling of endogenous retrovirus replication (CLEVR) reveals de novo insertions of the gypsy retrotransposable element in cell culture and in both neurons and glial cells of aging fruit flies

Newsemia
by Yung-Heng Chang, Richard M. Keegan, Lisa Prazak, Josh Dubnau Evidence is rapidly mounting that transposable element (TE) expression and replication may impact biology more...
Latest News

Endogenous GLP-1 in lateral septum promotes satiety and suppresses motivation for food in mice

Newsemia
Terrill, SJ; Holt, MK; Maske, CB; Abrams, N; Reimann, F; Trapp, S; Williams, DL; (2019) Endogenous GLP-1 in lateral septum promotes satiety and suppresses motivation...
AI/ML

Competing endogenous RNA expression profiling in pre-eclampsia identifies hsa_circ_0036877 as a potential novel blood biomarker for early pre-eclampsia.

Newsemia
Related Articles Competing endogenous RNA expression profiling in pre-eclampsia identifies hsa_circ_0036877 as a potential novel blood biomarker for early pre-eclampsia. Clin Epigenetics. 2018;10:48 Authors: Hu...
Gastroenterology

Long non-coding RNA ZNFX1-AS1 promotes the tumor progression and metastasis of colorectal cancer by acting as a competing endogenous RNA of miR-144 to regulate EZH2 expression

Newsemia
Long non-coding RNA ZNFX1-AS1 promotes the tumor progression and metastasis of colorectal cancer by acting as a competing endogenous RNA of miR-144 to regulate EZH2...
Latest News

Scientists identify endogenous activator of sigma-1 receptors in human cells

Newsemia
Cells communicate through complex mechanisms that typically involve receptors and ligands that bind to them. Endogenous ligands, produced by the body, have been identified for...
Pharma / Biotech

From Endogenous Compounds as Biomarkers to Plasma-Derived Nanovesicles as Liquid Biopsy; Has the Golden Age of Translational PK-ADME-DDI Science Finally Arrived?

Newsemia
Related Articles From Endogenous Compounds as Biomarkers to Plasma-Derived Nanovesicles as Liquid Biopsy; Has the Golden Age of Translational PK-ADME-DDI Science Finally Arrived? Clin Pharmacol...
Neurology

Clinical presentation of 54 patients with endogenous hyperinsulinaemic hypoglycaemia: a neurological chameleon (observational study).

Newsemia
Related Articles Clinical presentation of 54 patients with endogenous hyperinsulinaemic hypoglycaemia: a neurological chameleon (observational study). Swiss Med Wkly. 2018 Nov 05;148:w14682 Authors: Valente LG,...
Latest News

Data from Axcella’s AXA1125 Program Supports New Approach Leveraging Endogenous Metabolic Modulators to Reprogram Cellular Physiology

Newsemia
CAMBRIDGE, Mass.–(BUSINESS WIRE)–#AASLD–Data from Axcella’s AXA1125 Program Supports New Approach Leveraging Endogenous Metabolic Modulators to Reprogram Cellular Physiology Source link...

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