Tag: editing

Cardiology

Generation of a NONO homozygous knockout human induced pluripotent stem cell line by CRISPR/Cas9 editing.

Newsemia
Generation of a NONO homozygous knockout human induced pluripotent stem cell line by CRISPR/Cas9 editing. Stem Cell Res. 2020 Jul 08;47:101893 Authors: Yi T, Bai...
Latest News

Verve Therapeutics Presents New Data in Non-Human Primates Validating Gene Editing as a Treatment Approach for Coronary Heart Disease at the ISSCR 2020 Virtual Annual Meeting

Newsemia
CAMBRIDGE, Mass.–(BUSINESS WIRE)–Verve Therapeutics, a next-generation cardiovascular company, today announced the presentation of new preclinical proof-of-concept data in non-human primates that demonstrate the successful use...
Biology

ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons

Newsemia
by Jelmer Willems, Arthur P. H. de Jong, Nicky Scheefhals, Eline Mertens, Lisa A. E. Catsburg, Rogier B. Poorthuis, Fred de Winter, Joost Verhaagen, Frank...
Gastroenterology

Editing Myosin VB Gene to Create Porcine Model of Microvillus Inclusion Disease, With Microvillus-lined Inclusions and Alterations in Sodium Transporters

Newsemia
Microvillus inclusion disease (MVID) is caused by inactivating mutations in the myosin VB gene (MYO5B). MVID is a complex disorder characterized by chronic, watery, life-threatening...
Biology

Reassessing the contribution of the Na+/H+ exchanger Nhe3b to Na+ uptake in zebrafish (Danio rerio) using CRISPR/Cas9 gene editing [RESEARCH ARTICLE]

Newsemia
Alex M. Zimmer, Khatereh Shir-Mohammadi, Raymond W. M. Kwong, and Steve F. Perry Freshwater fishes absorb Na+ from their dilute environment using ion-transporting cells. In...
Biology

Reassessing the contribution of the Na+/H+ exchanger Nhe3b to Na+ uptake in zebrafish (Danio rerio) using CRISPR/Cas9 gene editing [RESEARCH ARTICLE]

Newsemia
Alex M. Zimmer, Khatereh Shir-Mohammadi, Raymond W. M. Kwong, and Steve F. Perry Freshwater fishes absorb Na+ from their dilute environment using ion-transporting cells. In...

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