Tag : drugdrug

Pharma / Biotech

Clinical implications of trials investigating drug-drug interactions between cannabidiol and enzyme inducers or inhibitors or common antiseizure drugs.

Newsemia
Clinical implications of trials investigating drug-drug interactions between cannabidiol and enzyme inducers or inhibitors or common antiseizure drugs. Epilepsia. 2020 Sep 12;: Authors: Patsalos PN,...
Pharma / Biotech

Drug-drug interaction of rivaroxaban and calcium channel blockers in patients aged 80 years and older with nonvalvular atrial fibrillation.

Newsemia
Related Articles Drug-drug interaction of rivaroxaban and calcium channel blockers in patients aged 80 years and older with nonvalvular atrial fibrillation. Drug Metab Pers Ther....
AI/ML

Efficient prediction of drug-drug interaction using deep learning models.

Newsemia
Related Articles Efficient prediction of drug-drug interaction using deep learning models. IET Syst Biol. 2020 Aug;14(4):211-216 Authors: Kumar Shukla P, Kumar Shukla P, Sharma P,...
Pharma / Biotech

A Phase 2, Double-Blind, Placebo-Controlled Trial to Investigate Potential Drug-Drug Interactions Between Cannabidiol and Clobazam.

Newsemia
Related Articles A Phase 2, Double-Blind, Placebo-Controlled Trial to Investigate Potential Drug-Drug Interactions Between Cannabidiol and Clobazam. J Clin Pharmacol. 2020 Jul 11;: Authors: VanLandingham...
Pharma / Biotech

Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure and Support Dosing Recommendations for Potential Drug-Drug Interactions or in Special Populations: An Example Using Tofacitinib.

Newsemia
Related Articles Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure and Support Dosing Recommendations for Potential Drug-Drug Interactions or in Special Populations: An...
Pharma / Biotech

Understanding the Effect of Hydroxypropyl-β-Cyclodextrin on Fenebrutinib Absorption in an Itraconazole-Fenebrutinib Drug-Drug Interaction Study.

Newsemia
Related Articles Understanding the Effect of Hydroxypropyl-β-Cyclodextrin on Fenebrutinib Absorption in an Itraconazole-Fenebrutinib Drug-Drug Interaction Study. Clin Pharmacol Ther. 2020 Jun 14;: Authors: Durk MR,...
Pharma / Biotech

Absorption, Distribution, Metabolism, Excretion (ADME), Drug-drug interaction potential and Prediction of Human Pharmacokinetics of SUVN-G3031, a Novel Histamine 3 Receptor (H3R) inverse agonist in Clinical development for the treatment of Narcolepsy.

Newsemia
Related Articles Absorption, Distribution, Metabolism, Excretion (ADME), Drug-drug interaction potential and Prediction of Human Pharmacokinetics of SUVN-G3031, a Novel Histamine 3 Receptor (H3R) inverse agonist...
Pharma / Biotech

Edoxaban and the Issue of Drug-Drug Interactions: From Pharmacology to Clinical Practice.

Newsemia
Related Articles Edoxaban and the Issue of Drug-Drug Interactions: From Pharmacology to Clinical Practice. Drugs. 2020 Jun 05;: Authors: Corsini A, Ferri N, Proietti M,...
Pharma / Biotech

[Drug-drug Interactions in Intensive Care].

Newsemia
[Drug-drug Interactions in Intensive Care]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2020 May;55(5):300-313 Authors: Drust A Abstract Drug-drug interactions are common problems in intensive care units. Numerous...
Pharma / Biotech

Pharmacologic treatment of transplant recipients infected with SARS-CoV-2: considerations regarding therapeutic drug monitoring and drug-drug interactions.

Newsemia
Related Articles Pharmacologic treatment of transplant recipients infected with SARS-CoV-2: considerations regarding therapeutic drug monitoring and drug-drug interactions. Ther Drug Monit. 2020 Apr 15;: Authors:...
Pharma / Biotech

In vitro inhibition of human cytochrome P450 enzymes by the novel atypical antipsychotic drug asenapine: a prediction of possible drug-drug interactions.

Newsemia
Related Articles In vitro inhibition of human cytochrome P450 enzymes by the novel atypical antipsychotic drug asenapine: a prediction of possible drug-drug interactions. Pharmacol Rep....
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Prediction of Clinical Transporter Mediated Drug‐Drug Interactions via Co‐measurement of Pitavastatin and Eltrombopag in Human Hepatocyte Models

Newsemia
Carter, SJ; Chouhan, B; Sharma, P; Chappell, MJ; (2020) Prediction of Clinical Transporter Mediated Drug‐Drug Interactions via Co‐measurement of Pitavastatin and Eltrombopag in Human Hepatocyte...
Pharma / Biotech

Safety and Pharmacokinetics of DS-1040 Drug-Drug Interactions With Aspirin, Clopidogrel, and Enoxaparin.

Newsemia
Safety and Pharmacokinetics of DS-1040 Drug-Drug Interactions With Aspirin, Clopidogrel, and Enoxaparin. J Clin Pharmacol. 2020 Feb 27;: Authors: Limsakun T, Dishy V, Mendell J,...
Pharma / Biotech

Value of quantifying ABC transporters by mass spectrometry and impact on in vitro-to-in vivo prediction of transporter-mediated drug-drug interactions of rivaroxaban.

Newsemia
Related Articles Value of quantifying ABC transporters by mass spectrometry and impact on in vitro-to-in vivo prediction of transporter-mediated drug-drug interactions of rivaroxaban. Eur J...
Pharma / Biotech

Physiologically based pharmacokinetic modelling of oxycodone drug-drug interactions.

Newsemia
Related Articles Physiologically based pharmacokinetic modelling of oxycodone drug-drug interactions. Biopharm Drug Dispos. 2020 Jan 10;: Authors: Rytkönen J, Ranta VP, Kokki M, Kokki H,...
Pharma / Biotech

Drug-Drug Interactions (DDIs) in Psychiatric Practice, Part 8: Relative Receptor Binding Affinity as a Way of Understanding the Differential Pharmacology of Currently Available Antidepressants.

Newsemia
Drug-Drug Interactions (DDIs) in Psychiatric Practice, Part 8: Relative Receptor Binding Affinity as a Way of Understanding the Differential Pharmacology of Currently Available Antidepressants. J...
Pharma / Biotech

Potential drug-drug interactions associated with clinical and laboratory findings at hospital admission.

Newsemia
Related Articles Potential drug-drug interactions associated with clinical and laboratory findings at hospital admission. Int J Clin Pharm. 2019 Dec 21;: Authors: Kovačević M, Vezmar...
Pharma / Biotech

Prediction of pH-Dependent Drug-Drug Interactions for Basic Drugs using Physiologically based Biopharmaceutics Modeling: Industry Case Studies.

Newsemia
Prediction of pH-Dependent Drug-Drug Interactions for Basic Drugs using Physiologically based Biopharmaceutics Modeling: Industry Case Studies. J Pharm Sci. 2019 Nov 25;: Authors: Mitra A,...

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