Tag : drug therapy

Cardiology

The Combination of Oral Anticoagulant and Antiplatelet Therapies: Stay One Step Ahead.

Newsemia
Related Articles The Combination of Oral Anticoagulant and Antiplatelet Therapies: Stay One Step Ahead. J Cardiovasc Pharmacol Ther. 2020 09;25(5):391-398 Authors: Lucà F, Giubilato S,...
Cardiology

Association Between Low-Dose Rivaroxaban With or Without Aspirin and Ischemic Stroke Subtypes: A Secondary Analysis of the COMPASS Trial.

Newsemia
Related Articles Association Between Low-Dose Rivaroxaban With or Without Aspirin and Ischemic Stroke Subtypes: A Secondary Analysis of the COMPASS Trial. JAMA Neurol. 2020 01...
Cardiology

Long-Term Safety and Efficacy of Durable Polymer Cobalt-Chromium Everolimus-Eluting Stents in Patients at High Bleeding Risk: A Patient-Level Stratified Analysis From Four Postapproval Studies.

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Related Articles Long-Term Safety and Efficacy of Durable Polymer Cobalt-Chromium Everolimus-Eluting Stents in Patients at High Bleeding Risk: A Patient-Level Stratified Analysis From Four Postapproval...
Cardiology

Resveratrol-mediated glycemic regulation is blunted by curcumin and is associated to modulation of gut microbiota.

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Related Articles Resveratrol-mediated glycemic regulation is blunted by curcumin and is associated to modulation of gut microbiota. J Nutr Biochem. 2019 10;72:108218 Authors: Sreng N,...
AI/ML

A randomized controlled trial for measuring effects on cognitive functions of adding ketamine to propofol during sedation for colonoscopy.

Newsemia
Related Articles A randomized controlled trial for measuring effects on cognitive functions of adding ketamine to propofol during sedation for colonoscopy. Medicine (Baltimore). 2020 Sep...
Cardiology

Duration of Dual Antiplatelet Therapy in Patients with CKD and Drug-Eluting Stents: A Meta-Analysis.

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Related Articles Duration of Dual Antiplatelet Therapy in Patients with CKD and Drug-Eluting Stents: A Meta-Analysis. Clin J Am Soc Nephrol. 2019 06 07;14(6):810-822 Authors:...
AI/ML

Stratification and prediction of drug synergy based on target functional similarity.

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Related Articles Stratification and prediction of drug synergy based on target functional similarity. NPJ Syst Biol Appl. 2020 06 02;6(1):16 Authors: Yang M, Jaaks P,...
Neurology

Vigabatrin add-on therapy for drug-resistant focal epilepsy.

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Related Articles Vigabatrin add-on therapy for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2020 07 30;7:CD007302 Authors: Bresnahan R, Gianatsi M, Maguire MJ, Tudur Smith...
AI/ML

Exploring the Correlation between the Cognitive Benefits of Drug Combinations in a Clinical Database and the Efficacies of the Same Drug Combinations Predicted from a Computational Model.

Newsemia
Related Articles Exploring the Correlation between the Cognitive Benefits of Drug Combinations in a Clinical Database and the Efficacies of the Same Drug Combinations Predicted...
Cardiology

Incremental risk of cardiovascular disease and/or chronic kidney disease for future ASCVD and mortality in patients with type 2 diabetes mellitus: ACCORD trial.

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Related Articles Incremental risk of cardiovascular disease and/or chronic kidney disease for future ASCVD and mortality in patients with type 2 diabetes mellitus: ACCORD trial....
Pharma / Biotech

Attention-Deficit Hyperactivity Disorder, Disruptive Behaviors, and Drug Shortage.

Newsemia
Related Articles Attention-Deficit Hyperactivity Disorder, Disruptive Behaviors, and Drug Shortage. J Dev Behav Pediatr. 2019 Jul/Aug;40(6):489-491 Authors: Hastings E, Poon J, Robert S, Nyp SS...
Cardiology

Anti-thrombotic options for secondary prevention in patients with chronic atherosclerotic vascular disease: what does COMPASS add?

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Related Articles Anti-thrombotic options for secondary prevention in patients with chronic atherosclerotic vascular disease: what does COMPASS add? Eur Heart J. 2019 05 07;40(18):1466-1471 Authors:...
Pharma / Biotech

Rifampin Induces Expression of P-glycoprotein on the THP1 Cell-Derived Macrophages, Causing Decrease Intramacrophage Concentration of Prothionamide.

Newsemia
Related Articles Rifampin Induces Expression of P-glycoprotein on the THP1 Cell-Derived Macrophages, Causing Decrease Intramacrophage Concentration of Prothionamide. J Pharm Sci. 2019 09;108(9):3106-3111 Authors: Hasanuzzaman...
Neurology

The influence of mean arterial pressure on the efficacy and safety of dual antiplatelet therapy in minor stroke or transient ischemic attack patients.

Newsemia
Related Articles The influence of mean arterial pressure on the efficacy and safety of dual antiplatelet therapy in minor stroke or transient ischemic attack patients....
Cardiology

Patent foramen ovale and long-term risk of ischaemic stroke after surgery.

Newsemia
Related Articles Patent foramen ovale and long-term risk of ischaemic stroke after surgery. Eur Heart J. 2019 03 14;40(11):914-924 Authors: Friedrich S, Ng PY, Platzbecker...
Biology

Combining antibiotics with antivirulence compounds can have synergistic effects and reverse selection for antibiotic resistance in <i>Pseudomonas aeruginosa</i>

Newsemia
by Chiara Rezzoagli, Martina Archetti, Ingrid Mignot, Michael Baumgartner, Rolf Kümmerli Antibiotics are losing efficacy due to the rapid evolution and spread of resistance. Treatments...
AI/ML

Artificial intelligence in drug combination therapy.

Newsemia
Related Articles Artificial intelligence in drug combination therapy. Brief Bioinform. 2019 07 19;20(4):1434-1448 Authors: Tsigelny IF Abstract Currently, the development of medicines for complex diseases...
Biology

Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations

Newsemia
by Elsa Hansen, Jason Karslake, Robert J. Woods, Andrew F. Read, Kevin B. Wood Standard infectious disease practice calls for aggressive drug treatment that rapidly...
Biology

Delayed death in the malaria parasite <i>Plasmodium falciparum</i> is caused by disruption of prenylation-dependent intracellular trafficking

Newsemia
by Kit Kennedy, Simon A. Cobbold, Eric Hanssen, Jakob Birnbaum, Natalie J. Spillman, Emma McHugh, Hannah Brown, Leann Tilley, Tobias Spielmann, Malcolm J. McConville, Stuart...

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