Tag : drug development

Neurology

Negative Phase 2 Trial Data Ends Development of PSP Drug

Newsemia
Phase 2 trial results show gosuranemab did not meet primary or key secondary endpoints in patients with progressive supranuclear palsy, leading to discontinuation of the...
Neurology

FDA Okays Cenobamate (Xcopri) for Focal Epilepsy

Newsemia
The FDA has approved cenobamate for seizures in adults with focal epilepsy based on results from two trials of more than 600 patients, as well...
AI/ML

Computer science in service of medicine

Newsemia
MIT’s Ray and Maria Stata Center (Building 32), known for its striking outward appearance, is also designed to foster collaboration among the people inside. Sitting...
AI/ML

Detecting patients’ pain levels via their brain signals

Newsemia
Researchers from MIT and elsewhere have developed a system that measures a patient’s pain level by analyzing brain activity from a portable neuroimaging device. The...
AI/ML

Model predicts cognitive decline due to Alzheimer’s, up to two years out

Newsemia
A new model developed at MIT can help predict if patients at risk for Alzheimer’s disease will experience clinically significant cognitive decline due to the...
AI/ML

Merging cell datasets, panorama style

Newsemia
A new algorithm developed by MIT researchers takes cues from panoramic photography to merge massive, diverse cell datasets into a single source that can be...
AI/ML

New approach could accelerate efforts to catalogue vast numbers of cells

Newsemia
Artistic sketches can be used to capture details of a scene in a simpler image. MIT researchers are now bringing that concept to computational biology,...
AI/ML

Model learns how individual amino acids determine protein function

Newsemia
A machine-learning model from MIT researchers computationally breaks down how segments of amino acid chains determine a protein’s function, which could help researchers design and...
AI/ML

Using machine learning for medical solutions

Newsemia
Pharmaceutical companies spend a lot of time testing potential drugs, and they end up wasting  much of that effort on candidates that don’t pan out....
Neurology

Off-Label Drug Research Generates 'Medical Uncertainty'

Newsemia
Research that explores/supports off-label use of pregabalin and other medications may be misleading if early promising results are not subsequently validated, investigators suggest in a...
AI/ML

Cryptographic protocol enables greater collaboration in drug discovery

Newsemia
MIT researchers have developed a cryptographic system that could help neural networks identify promising drug candidates in massive pharmacological datasets, while keeping the data private....
AI/ML

Applying machine learning to challenges in the pharmaceutical industry

Newsemia
MIT continues its efforts to transform the process of drug design and manufacturing with a new MIT-industry consortium, the Machine Learning for Pharmaceutical Discovery and...

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