Tag: Drosophila melanogaster

Biology

Dilp-2–mediated PI3-kinase activation coordinates reactivation of quiescent neuroblasts with growth of their glial stem cell niche

Newsemia
by Xin Yuan, Conor W. Sipe, Miyuki Suzawa, Michelle L. Bland, Sarah E. Siegrist Dietary nutrients provide macromolecules necessary for organism growth and development. In...
Biology

A single-cell atlas of adult <i>Drosophila</i> ovary identifies transcriptional programs and somatic cell lineage regulating oogenesis

Newsemia
by Allison Jevitt, Deeptiman Chatterjee, Gengqiang Xie, Xian-Feng Wang, Taylor Otwell, Yi-Chun Huang, Wu-Min Deng Oogenesis is a complex developmental process that involves spatiotemporally regulated...
Biology

<i>Drosophila</i>-associated bacteria differentially shape the nutritional requirements of their host during juvenile growth

Newsemia
by Jessika Consuegra, Théodore Grenier, Patrice Baa-Puyoulet, Isabelle Rahioui, Houssam Akherraz, Hugo Gervais, Nicolas Parisot, Pedro da Silva, Hubert Charles, Federica Calevro, François Leulier The...
Biology

A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation

Newsemia
by Kotaro Tsuboyama, Tatsuya Osaki, Eriko Matsuura-Suzuki, Hiroko Kozuka-Hata, Yuki Okada, Masaaki Oyama, Yoshiho Ikeuchi, Shintaro Iwasaki, Yukihide Tomari Proteins are typically denatured and aggregated...
Biology

Snail synchronizes endocycling in a TOR-dependent manner to coordinate entry and escape from endoreplication pausing during the <i>Drosophila</i> critical weight checkpoint

Newsemia
by Jie Zeng, Nhan Huynh, Brian Phelps, Kirst King-Jones The final body size of any given individual underlies both genetic and environmental constraints. Both mammals...
Biology

Bellymount enables longitudinal, intravital imaging of abdominal organs and the gut microbiota in adult <i>Drosophila</i>

Newsemia
by Leslie Ann Jaramillo Koyama, Andrés Aranda-Díaz, Yu-Han Su, Shruthi Balachandra, Judy Lisette Martin, William B. Ludington, Kerwyn Casey Huang, Lucy Erin O’Brien Cell- and...
Biology

A role for triglyceride lipase <i>brummer</i> in the regulation of sex differences in <i>Drosophila</i> fat storage and breakdown

Newsemia
by Lianna W. Wat, Chien Chao, Rachael Bartlett, Justin L. Buchanan, Jason W. Millington, Hui Ju Chih, Zahid S. Chowdhury, Puja Biswas, Vivian Huang, Leah...
Biology

Glioblastoma cells vampirize WNT from neurons and trigger a JNK/MMP signaling loop that enhances glioblastoma progression and neurodegeneration

Newsemia
by Marta Portela, Varun Venkataramani, Natasha Fahey-Lozano, Esther Seco, Maria Losada-Perez, Frank Winkler, Sergio Casas-Tintó Glioblastoma (GB) is the most lethal brain tumor, and Wingless...
Biology

The tricellular vertex-specific adhesion molecule Sidekick facilitates polarised cell intercalation during <i>Drosophila</i> axis extension

Newsemia
by Tara M. Finegan, Nathan Hervieux, Alexander Nestor-Bergmann, Alexander G. Fletcher, Guy B. Blanchard, Bénédicte Sanson In epithelia, tricellular vertices are emerging as important sites...
Biology

Parental breeding age effects on descendants’ longevity interact over 2 generations in matrilines and patrilines

Newsemia
by Zachariah Wylde, Foteini Spagopoulou, Amy K. Hooper, Alexei A. Maklakov, Russell Bonduriansky Individuals within populations vary enormously in mortality risk and longevity, but the...
Biology

The Hippo pathway integrates PI3K–Akt signals with mechanical and polarity cues to control tissue growth

Newsemia
by Nerea Borreguero-Muñoz, Georgina C. Fletcher, Mario Aguilar-Aragon, Ahmed Elbediwy, Zoé I. Vincent-Mistiaen, Barry J. Thompson The Hippo signalling pathway restricts cell proliferation in animal...
Biology

Selective suppression and recall of long-term memories in <i>Drosophila</i>

Newsemia
by Dominique Siegenthaler, Benjamin Escribano, Vanessa Bräuler, Jan Pielage Adaptive decision-making depends on the formation of novel memories. In Drosophila, the mushroom body (MB) is...
Biology

Fully automated leg tracking of <i>Drosophila</i> neurodegeneration models reveals distinct conserved movement signatures

Newsemia
by Shuang Wu, Kah Junn Tan, Lakshmi Narasimhan Govindarajan, James Charles Stewart, Lin Gu, Joses Wei Hao Ho, Malvika Katarya, Boon Hui Wong, Eng-King Tan,...
Biology

CRL4<sup>Mahj</sup> E3 ubiquitin ligase promotes neural stem cell reactivation

Newsemia
by Phuong Thao Ly, Ye Sing Tan, Chwee Tat Koe, Yingjie Zhang, Gengqiang Xie, Sharyn Endow, Wu-Min Deng, Fengwei Yu, Hongyan Wang The ability of...
Biology

Cellular labeling of endogenous retrovirus replication (CLEVR) reveals de novo insertions of the gypsy retrotransposable element in cell culture and in both neurons and glial cells of aging fruit flies

Newsemia
by Yung-Heng Chang, Richard M. Keegan, Lisa Prazak, Josh Dubnau Evidence is rapidly mounting that transposable element (TE) expression and replication may impact biology more...
Biology

Islands of retroelements are major components of <i>Drosophila</i> centromeres

Newsemia
by Ching-Ho Chang, Ankita Chavan, Jason Palladino, Xiaolu Wei, Nuno M. C. Martins, Bryce Santinello, Chin-Chi Chen, Jelena Erceg, Brian J. Beliveau, Chao-Ting Wu, Amanda...
Biology

Simu-dependent clearance of dying cells regulates macrophage function and inflammation resolution

Newsemia
by Hannah Grace Roddie, Emma Louise Armitage, Jonathon Alexis Coates, Simon Andrew Johnston, Iwan Robert Evans Macrophages encounter and clear apoptotic cells during normal development...
Biology

Genome-wide sexually antagonistic variants reveal long-standing constraints on sexual dimorphism in fruit flies

Newsemia
by Filip Ruzicka, Mark S. Hill, Tanya M. Pennell, Ilona Flis, Fiona C. Ingleby, Richard Mott, Kevin Fowler, Edward H. Morrow, Max Reuter The evolution...

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