dopamine
- December 3, 2019
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- Tags: AllostericCellcomputationalDesigndopaminedrugsEnzymefunctionsGPCRligandmedicineMethodmoleculepredictproteinproteinsReceptorSerotonin
Called the "second secret of life", allostery is one of the most fundamental processes of biology and has been a central focus among scientists across the life sciences spectrum, from...
Read more- November 30, 2019
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- Tags: alter brainblood pressurebodyboost productivitydopamineGratitudehealth benefitsimprove outlookimprove sleeplower inflammationreduce depressionSerotoninThankfulthanks
Per a new research, the act of being thankful for the things in your life can bring so many health benefits. Source link
Read more- November 19, 2019
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- Tags: asthmaAsthma; Allergy; Lung Cancer; Lung Disease; Child Psychology; Neuroscience; Child Development; SchizophreniaChildhooddopamineEvidenceinfluencedmiceneurotransmitter
Neurons that produce the neurotransmitter dopamine communicate with T cells to enhance allergic inflammation in the lungs of young mice but not older mice, researchers report. The findings potentially explain...
Read more- November 15, 2019
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- Tags: AdvbackBackscataplexycontinuous positive airway pressurecontinuous positive airway pressure (cpap)CPAPdopaminedorsalehlers-danlos syndromeEMAEuropeEuropeanexcessive daytime sleepinessheadachehypersomniaidiopathic hypersomniainsomnianarcolepsyObstructive Sleep Apneaobstructive sleep apnea-hypopnea syndromeOSAPanelselect sleep disorderssleep apneasleep disorderSolriamfetolSunosi
The dual-acting dopamine and norepinephrine reuptake inhibitor showed durable effects in reducing excessive sleepiness in patients with narcolepsy or obstructive sleep apnea (OSA). International Approvals Source link
Read more- November 10, 2019
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- Tags: alprazolamalprazolam tabletsContaminationdopamineGABAopioid crisispatientsPutsRECALLriskusp c-iv 0.5 mgXanax
A batch of contaminated Alprazolam medication was recalled in a preventive measure. Source link
Read more- November 9, 2019
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- Tags: addictionbrainbrainscocainedisconnectdopamineNeurosciencestriatum
neurosciencestuff: Researchers at UTSA have revealed significant insight into cocaine addiction, a phenomenon which has grown significantly in the United States since 2015.Now new data by UTSA shows how the...
Read more- October 31, 2019
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- Tags: AffectsaffinityalicyclicAminesbis4fluorophenylmethylsulfinylalkylCitation searchdopamineEntrezfunctionalizingJournal ArticlesMedical JournalsMEDLINEMetabolicNational Center for Biotechnology InformationNCBINitrogenNLMpub medPubMedrelationshipsSelectivitySeriesstabilityStructureactivityterminalTransporterUnited States National Library of Medicine
Related Articles Structure-Activity Relationships for a series of bis(4-fluorophenyl)methyl)sulfinyl)alkyl alicyclic amines at the dopamine transporter: functionalizing the terminal nitrogen affects affinity, selectivity and metabolic stability. J Med Chem. 2019 Oct...
Read more- October 30, 2019
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- Tags: AnhedoniaanxietybraindepressionDiagnosedopaminefunctiongenesManagemedicineNeuronneuronsNeuroscienceresearchSerotoninstress
Ever heard of the lateral habenula? Very few, outside of neuroscience, probably have. Yet a new study, published in the journal Neuron, shows that characteristic changes in the way this...
Read more- October 29, 2019
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- Tags: braincausaldiscoverydopaminedrugsEnzymeGenegene expressionGenetichydrogenHydrogen SulphideinflammationLinkmedicineMutationpathophysiologyproteinschizophreniastresssulfide
Researchers from the RIKEN Center for Brain Science in Japan have found certain chemical markers that are associated with schizophrenia. They worked with lab mice with models of schizophrenia as...
Read more- October 28, 2019
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- Tags: BiomarkerbrainDNAdopaminedrugsEnzymeGenegene expressionGoodhairlevelsmedicineMPSTproteinresearchschizophreniastress
Working with model mice, post-mortem human brains, and people with schizophrenia, researchers at the RIKEN Center for Brain Science in Japan have discovered that a subtype of schizophrenia is related...
Read more- October 20, 2019
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- Tags: braindevelopdiseasedopamineGeneticmedicineneurologyneuronsOCTParkinson's DiseaseParkinson039spatientderivedresearchScientistsstrategytreatment
Northwestern Medicine scientists have used patient-derived neurons to develop and test a new strategy to treat Parkinson's disease by mitigating the effects of harmful genetic mutations, as detailed in a...
Read more- October 20, 2019
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- Tags: Animal performanceCellcontributionsControldissociatesdopaminelearningmediummicemorphinemotorNeostriatumNeurofibromatosis type 1neuronsNF1cAMPrewardsignalingspinystriataltypespecificValuation
by Laurie P. Sutton, Brian S. Muntean, Olga Ostrovskaya, Stefano Zucca, Maria Dao, Cesare Orlandi, Chenghui Song, Keqiang Xie, Kirill A. Martemyanov The striatum plays a fundamental role in motor...
Read more- October 20, 2019
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- Tags: administeredbraindeadcontractiledonorsdopamineDopamine (CID: 681);N-octanoyl dopamine;N-octanoyl dopamine (CID: 16389464);brain death;dopamine;heart transplantation;left ventricular function;radical scavengerfunctiongraftheartNoctanoylProtectingRecipientssuperiorTransplant
N-octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors. Pharmacol Res. 2019 Oct 16;:104503 Authors: Loganathan S, Guo...
Read more- October 18, 2019
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- Tags: antipsychoticbipolarBipolar DisorderbraindepressiondiseasedisorderdopaminedrugsGeneticIncreaselithiummaniamuscleParkinson's DiseaseParkinson039sposturerisktremor
A review published by the JAMA Network has found that the risk of Parkinson's disease is significantly higher in those with bipolar disorder. Source link
Read more- September 8, 2019
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- Tags: addictionalcohol abusealcohol addictionAlcoholismAntidepressantantidepressant drugbooksbrainclinical researchclinical studiesclinical trialsdepressiondopaminedrug (antidepressant)elderly/concerns of older adultsGABAgeriatrics (elder care)headacheJournalsmajor depressionMajor Depressive Disordermedical literaturemodulatorneurotransmitterPromisingrecremissiontextbooksunipolar depression
Most antidepressants target monoaminergic neurotransmitters. A novel GABA modulator may open a new range of therapeutic possibilities for patients with major depression. Medscape Medical News Source link
Read more- August 29, 2019
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- Tags: Clinical TrialdopamineDrugEfficacyInvestigationalMedical SchoolmedicineMovement disordersNeuroscienceOpenlabelPilotPsychiatryreducesresearchspeechstudystutteringsymptoms
A team led by a psychiatrist at the University of California, Riverside, has tested the orally administered investigational medication ecopipam on adults who stutter in an open-label, uncontrolled clinical trial...
Read more- August 20, 2019
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- Tags: book chaptersconference proceedingsdigital web resourcesdiscoverydistinctdopamineincidentalJournal ArticlesmemoryNoradrenalineopen accessopen access repositoryresearchrolesthesesuclucl discoveryucl libraryucl research
Hauser, TU; Eldar, E; Purg, N; Moutoussis, M; Dolan, RJ; (2019) Distinct roles of dopamine and noradrenaline in incidental memory. Journal of Neuroscience 10.1523/JNEUROSCI.0401-19.2019 . (In press). Source link
Read more- August 20, 2019
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- Tags: BrowndopaminefathypothalamicregulatessignallingThermogenesis
Hypothalamic dopamine signalling regulates brown fat thermogenesis Source link
Read moreDopamine and serotonin, or the 'happy hormones,' play key roles in mood, depression, and appetite, among other things. Learn about similarities, differences, and what happens when they are out of...
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