Tag: Dolutegravir

Pharma / Biotech

HPLC-MS/MS method for the simultaneous quantification of dolutegravir, elvitegravir, rilpivirine, darunavir, ritonavir, raltegravir and raltegravir-╬▓-d-glucuronide in human plasma.

Newsemia
Related Articles HPLC-MS/MS method for the simultaneous quantification of dolutegravir, elvitegravir, rilpivirine, darunavir, ritonavir, raltegravir and raltegravir-╬▓-d-glucuronide in human plasma. J Pharm Biomed Anal. 2020...
Pharma / Biotech

Prediction of dolutegravir pharmacokinetics and dose optimization in neonates via physiologically based pharmacokinetic (PBPK) modelling.

Newsemia
Related Articles Prediction of dolutegravir pharmacokinetics and dose optimization in neonates via physiologically based pharmacokinetic (PBPK) modelling. J Antimicrob Chemother. 2019 Dec 20;: Authors: Bunglawala...
Latest News

ViiV Healthcare announces phase III study meets primary endpoint, demonstrating the ability to control HIV-1 with a 2-drug regimen of dolutegravir plus lamivudine in virally suppressed patients switching from a TAF-containing, 3-drug regimen

Newsemia
LONDON–(BUSINESS WIRE)–ViiV Healthcare, the global specialist HIV company majority-owned by GSK, with Pfizer Inc. and Shionogi Limited as shareholders, today announced positive Week 48 results...
Pharma / Biotech

Population pharmacokinetics of dolutegravir: influence of drug-drug interactions in a real-life setting.

Newsemia
Related Articles Population pharmacokinetics of dolutegravir: influence of drug-drug interactions in a real-life setting. J Antimicrob Chemother. 2019 May 22;: Authors: Barcelo C, Aouri M,...
Latest News

Predicted antiviral activity of tenofovir versus abacavir in combination with a cytosine analogue and the integrase inhibitor dolutegravir in HIV-1-infected South African patients initiating or failing first-line ART

Newsemia
Derache, A; Iwuji, CC; Danaviah, S; Giandhari, J; Marcelin, A-G; Calvez, V; de Oliveira, T; … Gupta, RK; + view all Derache, A; Iwuji, CC;...
Neurology

PRAC Again Warns Against Dolutegravir Use During Pregnancy

Newsemia
The European Medicines Agency has confirmed its earlier precaution regarding the use of dolutegravir in women who are or who could become pregnant; it expects...

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