Tag: DNA replication

Biology

Transcription-induced formation of extrachromosomal DNA during yeast ageing

Newsemia
by Ryan M. Hull, Michelle King, Grazia Pizza, Felix Krueger, Xabier Vergara, Jonathan Houseley Extrachromosomal circular DNA (eccDNA) facilitates adaptive evolution by allowing rapid and...
Biology

KHDC3L mutation causes recurrent pregnancy loss by inducing genomic instability of human early embryonic cells

Newsemia
by Weidao Zhang, Zhongliang Chen, Dengfeng Zhang, Bo Zhao, Lu Liu, Zhengyuan Xie, Yonggang Yao, Ping Zheng Recurrent pregnancy loss (RPL) is an important complication...
Biology

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

Newsemia
by Cynthia J. Sakofsky, Natalie Saini, Leszek J. Klimczak, Kin Chan, Ewa P. Malc, Piotr A. Mieczkowski, Adam B. Burkholder, David Fargo, Dmitry A. Gordenin...
Biology

The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7

Newsemia
by Kerstin Köhler, Luis Sanchez-Pulido, Verena Höfer, Anika Marko, Chris P. Ponting, Ambrosius P. Snijders, Regina Feederle, Aloys Schepers, Dominik Boos Accurate genome duplication underlies...
Biology

Structure of the DP1–DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases

Newsemia
by Pierre Raia, Marta Carroni, Etienne Henry, Gérard Pehau-Arnaudet, Sébastien Brûlé, Pierre Béguin, Ghislaine Henneke, Erik Lindahl, Marc Delarue, Ludovic Sauguet PolD is an archaeal...
Latest News

Folate deficiency creates more damaging chromosomal abnormalities than previously known

Newsemia
Folate deficiency creates more problems in connection with DNA replication than researchers had hitherto assumed, researchers from the University of Copenhagen show in a new...

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