DNA damage – Newsemia

Differences in accumulation of genetic mutations could help predict lifespan, fertility

NewsemiaJune 19, 2020

by NewsemiaJune 19, 202000

Differences in the rate that genetic mutations accumulate in healthy young adults could help predict the remaining lifespan in both sexes and the remaining years...

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Researchers find direct link between MCL1 protein and cell-cycle checkpoint protein

NewsemiaApril 5, 2020

by NewsemiaApril 5, 2020022

Human cells respond to stresses like DNA damage, metabolic imbalance and starvation by first trying to repair the problem. Source link...

Biology

A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers

NewsemiaMarch 23, 2020

by NewsemiaMarch 23, 2020041

by Kunming Zhao, Xingwen Wang, Xuting Xue, Li Li, Ying Hu Ataxia-telangiectasia mutated (ATM) is an apical kinase of the DNA damage response following DNA...

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New repair mechanism for alcohol-induced DNA damage discovered

NewsemiaMarch 4, 2020

by NewsemiaMarch 4, 2020033

Researchers of the Hubrecht Institute in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way...

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"Jumping genes" within eggs determine their survival

NewsemiaJanuary 17, 2020

by NewsemiaJanuary 17, 2020012

Females are born with a finite supply of eggs and with age the genetic quality of the eggs decline say researchers from Carnegie Institute. The...

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Researchers confirm two new prognostic markers for triple negative breast cancer

NewsemiaDecember 6, 2019

by NewsemiaDecember 6, 201903

Physicians who treat patients with triple negative breast cancer have two new ways to predict which patients may benefit most from the well-established post-surgery treatment...

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New study uncovers multiple effects of little-known DNA repair protein

NewsemiaDecember 2, 2019

by NewsemiaDecember 2, 201907

Injury and repair are part of the normal life cycle of any tissue or organ in the human body. However, if macroscopic tears or breaks...

Biology

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

NewsemiaOctober 1, 2019

by NewsemiaOctober 1, 201904

by Cynthia J. Sakofsky, Natalie Saini, Leszek J. Klimczak, Kin Chan, Ewa P. Malc, Piotr A. Mieczkowski, Adam B. Burkholder, David Fargo, Dmitry A. Gordenin...

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Blood sugar levels linked to DNA damage and cancer in diabetics

NewsemiaAugust 26, 2019

by NewsemiaAugust 26, 201907

Increased blood sugar levels in diabetics could damage DNA and make the genome unstable, increasing the risk of certain cancers. Source link...

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Researchers explain how diabetes increases cancer risk

NewsemiaAugust 26, 2019

by NewsemiaAugust 26, 201905

For years, scientists have been trying to solve a medical mystery: Why do people with type 1 or type 2 diabetes have an increased risk...

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Targeted pancreatic cancer drug shows promise in clinical trials

NewsemiaAugust 16, 2019

by NewsemiaAugust 16, 201904

Researchers have conducted clinical trials with a new drug targeting pancreatic cancer and the initial results are promising. Source link...

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New leukemia treatment developed from common wild flower

NewsemiaAugust 1, 2019

by NewsemiaAugust 1, 201906

Researchers have discovered how to turn a compound from a common wildflower called Feverfew into a new treatment for leukemia. Source link...

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Discovery of protective protein could open door to better treatment of fast-growing cancer cells

NewsemiaAugust 1, 2019

by NewsemiaAugust 1, 201905

The discovery that an essential protein plays a protective role during cell division, could open the door to better targeted treatment of fast-growing cancer cells....

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Mechanism Behind Low Cancer Occurrence In Bats Signals Potential Treatment Strategies For Humans

NewsemiaJuly 4, 2019

by NewsemiaJuly 4, 201906

Cancer is a leading cause of death in aging populations. Despite decades of research, cancer treatments are still inefficient and have unacceptable side effects that...

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Researchers identify effective drug combinations for malignant brain tumor in mice

NewsemiaJune 14, 2019

by NewsemiaJune 14, 201903

Usually, scientists study the molecular biology of cancer to find new treatments, but sometimes, it is the other way round: when trying to find new...

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Human body is a mosaic pattern of DNA mutations, say researchers

NewsemiaJune 7, 2019

by NewsemiaJune 7, 201905

Researchers have discovered that the cells of the human body aren’t clones of a single DNA sequence, but are actually a mosaic of mutations. Source...

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Researchers identify new mechanism for accessing damaged DNA

NewsemiaMay 31, 2019

by NewsemiaMay 31, 201903

UV light damages the DNA of skin cells, which can lead to skin cancer. Source link...

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Viral study reveals new way to prevent kidney damage following organ transplant

NewsemiaMay 30, 2019

by NewsemiaMay 30, 201908

While studying one of the smallest DNA viruses known, Sunnie Thompson, Ph.D., may have found a new way to help prevent kidney damage following organ...

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Yeast species thrives, despite losing DNA repair genes years ago

NewsemiaMay 22, 2019

by NewsemiaMay 22, 201904

Researchers have discovered an ancient species of budding yeast that has lost dozens of DNA repair genes, without any adverse effects. Source link...

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A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

NewsemiaApril 6, 2019

by NewsemiaApril 6, 201906

A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has now been shown also to...

Newsemia

Tag: DNA damage

Differences in accumulation of genetic mutations could help predict lifespan, fertility

Researchers find direct link between MCL1 protein and cell-cycle checkpoint protein

A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers

New repair mechanism for alcohol-induced DNA damage discovered

"Jumping genes" within eggs determine their survival

Researchers confirm two new prognostic markers for triple negative breast cancer

New study uncovers multiple effects of little-known DNA repair protein

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

Blood sugar levels linked to DNA damage and cancer in diabetics

Researchers explain how diabetes increases cancer risk

Targeted pancreatic cancer drug shows promise in clinical trials

New leukemia treatment developed from common wild flower

Discovery of protective protein could open door to better treatment of fast-growing cancer cells

Mechanism Behind Low Cancer Occurrence In Bats Signals Potential Treatment Strategies For Humans

Researchers identify effective drug combinations for malignant brain tumor in mice

Human body is a mosaic pattern of DNA mutations, say researchers

Researchers identify new mechanism for accessing damaged DNA

Viral study reveals new way to prevent kidney damage following organ transplant

Yeast species thrives, despite losing DNA repair genes years ago

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

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