DNA damage

Long noncoding RNAs: p53’s secret weapon in the fight against cancer?

[ad_1] by Emily Dangelmaier, Sarah B. Lazar, Ashish Lal p53 regulates the expression of hundreds of genes. Recent surprising observations indicate that no single protein-coding gene controls the tumor suppressor...

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Research sheds light on how motor enzyme can promote genome integrity

[ad_1] Approximately one per cent of each organism's genome encodes helicases. Helicases are mostly known as motor enzymes that can unwrap double-stranded DNA by use of energy. Source link [ad_2]

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Researchers uncover how the immune system protects from bowel cancer

[ad_1] Researchers from Charité - Universitätsmedizin Berlin have discovered a protective mechanism which is used by the body to protect intestinal stem cells from turning cancerous. Source link [ad_2]

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Sleep deprivation linked with DNA damage

[ad_1] Sleep deprivation was associated with DNA damage in a new Anesthesia study. In the observational study on 49 healthy full-time doctors who had their blood analyzed at different time...

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Novel biomarker links tumor progression to genome instability

[ad_1] Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in...

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Sperm health may play a role in recurrent miscarriages

[ad_1] The early-stage study, from scientists at Imperial College London, investigated the sperm quality of 50 men whose partners had suffered three or more consecutive miscarriages. Source link [ad_2]

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Scientists reveal how DNA damage leads to cancer and hereditary diseases

[ad_1] Scientists revealed how DNA damage influences mutations. Turned out that its contribution to mutagenesis was underestimated and many of the inheritance mutations are caused not by errors in DNA...

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Biological aging caused by cancer treatments correlates with cognitive decline

[ad_1] Cancer treatments are suspected to accelerate certain aging processes in the body. A new study has found that indicators of such biological aging correlate with declines in cognitive function...

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Failure of genetic repair system leads to chromosomal chaos

[ad_1] Scientists at the German Cancer Research Center have now found a cause for the frequent catastrophic events in the genetic material of cancer cells that have only been known...

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Study offers new hope to patients with rare brain cancer

[ad_1] sGBM is a rare type of brain cancer in adults. The incidence varies from 2 to 5 per million people per year. For example, if Hong Kong's base population...

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Invasion of the P elements: Tolerance is not futile

[ad_1] by Colin D. Meiklejohn, Justin P. Blumenstiel Organisms are locked in an eternal struggle with parasitic DNA sequences that live inside their genomes and wreak havoc on their host’s...

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Loss of tumor protein p53 helps cancer cells grow in hostile environment

Researchers have discovered a novel consequence of loss of the tumor protein p53 that promotes cancer development, according to new findings in eLife. Source link

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Zinc Eaten at Levels Found in Biofortified Crops Reduces 'Wear and Tear' on DNA

A new study by researchers from the UCSF Benioff Children's Hospital Oakland Research Institute (CHORI) shows that a modest 4 milligrams of extra zinc a day in the diet can...

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Study Reports Possible Novel Method for Stopping Untreatable Pediatric Brain Cancer

Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in...

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rDNA Instability and SIRT7 in Cellular Senescence

As the research and development community devotes ever greater resources to the development of senolytic rejuvenation therapies based on selective destruction of senescent cells, further exploration of the biochemistry of...

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A virus-acquired host cytokine controls systemic aging by antagonizing apoptosis

by Mohamed Mlih, Mobina Khericha, Christine Birdwell, A. Phillip West, Jason Karpac Aging is characterized by degeneration of unique tissues. However, dissecting the interconnectedness of tissue aging remains a challenge....

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Insecticide exposure affects DNA and antioxidant enzymes activity in honey bee species Apis florea and A. dorsata: Evidence from Punjab, Pakistan.

Related ArticlesInsecticide exposure affects DNA and antioxidant enzymes activity in honey bee species Apis florea and A. dorsata: Evidence from Punjab, Pakistan. Sci Total Environ. 2018 Sep 01;635:1292-1301 Authors: Hayat...

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