DNA damage

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

[ad_1] A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has now been shown also to play a key role...

Read more
New research opens possibility of using sperm taken from testicles to overcome infertility

[ad_1] Scientists have found that sperm DNA from the testicles of many infertile men is as good as that of ejaculated sperm of fertile men. This may explain a major...

Read more
Spontaneously slow-cycling subpopulations of human cells originate from activation of stress-response pathways

by Mingwei Min, Sabrina L. Spencer Slow-cycling subpopulations exist in bacteria, yeast, and mammalian systems. In the case of cancer, slow-cycling subpopulations have been proposed to give rise to drug...

Read more
Long noncoding RNAs: p53’s secret weapon in the fight against cancer?

[ad_1] by Emily Dangelmaier, Sarah B. Lazar, Ashish Lal p53 regulates the expression of hundreds of genes. Recent surprising observations indicate that no single protein-coding gene controls the tumor suppressor...

Read more
Research sheds light on how motor enzyme can promote genome integrity

[ad_1] Approximately one per cent of each organism's genome encodes helicases. Helicases are mostly known as motor enzymes that can unwrap double-stranded DNA by use of energy. Source link [ad_2]

Read more
Researchers uncover how the immune system protects from bowel cancer

[ad_1] Researchers from Charité - Universitätsmedizin Berlin have discovered a protective mechanism which is used by the body to protect intestinal stem cells from turning cancerous. Source link [ad_2]

Read more
Sleep deprivation linked with DNA damage

[ad_1] Sleep deprivation was associated with DNA damage in a new Anesthesia study. In the observational study on 49 healthy full-time doctors who had their blood analyzed at different time...

Read more
Novel biomarker links tumor progression to genome instability

[ad_1] Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in...

Read more
Sperm health may play a role in recurrent miscarriages

[ad_1] The early-stage study, from scientists at Imperial College London, investigated the sperm quality of 50 men whose partners had suffered three or more consecutive miscarriages. Source link [ad_2]

Read more
Scientists reveal how DNA damage leads to cancer and hereditary diseases

[ad_1] Scientists revealed how DNA damage influences mutations. Turned out that its contribution to mutagenesis was underestimated and many of the inheritance mutations are caused not by errors in DNA...

Read more
Biological aging caused by cancer treatments correlates with cognitive decline

[ad_1] Cancer treatments are suspected to accelerate certain aging processes in the body. A new study has found that indicators of such biological aging correlate with declines in cognitive function...

Read more
Failure of genetic repair system leads to chromosomal chaos

[ad_1] Scientists at the German Cancer Research Center have now found a cause for the frequent catastrophic events in the genetic material of cancer cells that have only been known...

Read more
Study offers new hope to patients with rare brain cancer

[ad_1] sGBM is a rare type of brain cancer in adults. The incidence varies from 2 to 5 per million people per year. For example, if Hong Kong's base population...

Read more
Invasion of the P elements: Tolerance is not futile

[ad_1] by Colin D. Meiklejohn, Justin P. Blumenstiel Organisms are locked in an eternal struggle with parasitic DNA sequences that live inside their genomes and wreak havoc on their host’s...

Read more
Loss of tumor protein p53 helps cancer cells grow in hostile environment

Researchers have discovered a novel consequence of loss of the tumor protein p53 that promotes cancer development, according to new findings in eLife. Source link

Read more
Zinc Eaten at Levels Found in Biofortified Crops Reduces 'Wear and Tear' on DNA

A new study by researchers from the UCSF Benioff Children's Hospital Oakland Research Institute (CHORI) shows that a modest 4 milligrams of extra zinc a day in the diet can...

Read more
Study Reports Possible Novel Method for Stopping Untreatable Pediatric Brain Cancer

Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in...

Read more
rDNA Instability and SIRT7 in Cellular Senescence

As the research and development community devotes ever greater resources to the development of senolytic rejuvenation therapies based on selective destruction of senescent cells, further exploration of the biochemistry of...

Read more
A virus-acquired host cytokine controls systemic aging by antagonizing apoptosis

by Mohamed Mlih, Mobina Khericha, Christine Birdwell, A. Phillip West, Jason Karpac Aging is characterized by degeneration of unique tissues. However, dissecting the interconnectedness of tissue aging remains a challenge....

Read more
Insecticide exposure affects DNA and antioxidant enzymes activity in honey bee species Apis florea and A. dorsata: Evidence from Punjab, Pakistan.

Related ArticlesInsecticide exposure affects DNA and antioxidant enzymes activity in honey bee species Apis florea and A. dorsata: Evidence from Punjab, Pakistan. Sci Total Environ. 2018 Sep 01;635:1292-1301 Authors: Hayat...

Read more