Tag : DNA damage

Biology

A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers

Newsemia
by Kunming Zhao, Xingwen Wang, Xuting Xue, Li Li, Ying Hu Ataxia-telangiectasia mutated (ATM) is an apical kinase of the DNA damage response following DNA...
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Researchers confirm two new prognostic markers for triple negative breast cancer

Newsemia
Physicians who treat patients with triple negative breast cancer have two new ways to predict which patients may benefit most from the well-established post-surgery treatment...
Biology

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

Newsemia
by Cynthia J. Sakofsky, Natalie Saini, Leszek J. Klimczak, Kin Chan, Ewa P. Malc, Piotr A. Mieczkowski, Adam B. Burkholder, David Fargo, Dmitry A. Gordenin...
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Researchers explain how diabetes increases cancer risk

Newsemia
For years, scientists have been trying to solve a medical mystery: Why do people with type 1 or type 2 diabetes have an increased risk...

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