Tag : Cytotoxic T cells

Biology

Yap suppresses T-cell function and infiltration in the tumor microenvironment

Newsemia
by Eleni Stampouloglou, Nan Cheng, Anthony Federico, Emily Slaby, Stefano Monti, Gregory L. Szeto, Xaralabos Varelas A major challenge for cancer immunotherapy is sustaining T-cell...
Biology

TSC1/mTOR-controlled metabolic–epigenetic cross talk underpins DC control of CD8<sup>+</sup> T-cell homeostasis

Newsemia
by Lei Shi, Xia Chen, Aiping Zang, Tiantian Li, Yanxiang Hu, Shixin Ma, Mengdie Lü, Huiyong Yin, Haikun Wang, Xiaoming Zhang, Bei Zhang, Qibin Leng,...
Biology

Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts

Newsemia
by Karin Schaeuble, Hélène Cannelle, Stéphanie Favre, Hsin-Ying Huang, Susanne G. Oberle, Daniel E. Speiser, Dietmar Zehn, Sanjiv A. Luther Lymphoid T-zone fibroblastic reticular cells...
Biology

The human lymph node microenvironment unilaterally regulates T-cell activation and differentiation

Newsemia
by Konstantin Knoblich, Sara Cruz Migoni, Susan M. Siew, Elizabeth Jinks, Baksho Kaul, Hannah C. Jeffery, Alfie T. Baker, Muath Suliman, Katerina Vrzalikova, Hisham Mehenna,...

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