Tag: Cytochrome

Pharma / Biotech

The atypical neuroleptics iloperidone and lurasidone inhibit human cytochrome P450 enzymes in vitro. Evaluation of potential metabolic interactions.

Newsemia
The atypical neuroleptics iloperidone and lurasidone inhibit human cytochrome P450 enzymes in vitro. Evaluation of potential metabolic interactions. Pharmacol Rep. 2020 Apr 11;: Authors: Danek...
Pharma / Biotech

In vitro inhibition of human cytochrome P450 enzymes by the novel atypical antipsychotic drug asenapine: a prediction of possible drug-drug interactions.

Newsemia
Related Articles In vitro inhibition of human cytochrome P450 enzymes by the novel atypical antipsychotic drug asenapine: a prediction of possible drug-drug interactions. Pharmacol Rep....
Pharma / Biotech

SuperCYPsPred-a web server for the prediction of cytochrome activity.

Newsemia
Related Articles SuperCYPsPred-a web server for the prediction of cytochrome activity. Nucleic Acids Res. 2020 Mar 17;: Authors: Banerjee P, Dunkel M, Kemmler E, Preissner...
Pharma / Biotech

P-glycoprotein (ABCB1/MDR1) limits brain accumulation and Cytochrome P450-3A (CYP3A) restricts oral availability of the novel FGFR4 inhibitor fisogatinib (BLU-554).

Newsemia
Related Articles P-glycoprotein (ABCB1/MDR1) limits brain accumulation and Cytochrome P450-3A (CYP3A) restricts oral availability of the novel FGFR4 inhibitor fisogatinib (BLU-554). Int J Pharm. 2019...
Pharma / Biotech

Heterotropic activation of flavonoids on cytochrome P450 3A4: a case example of alleviating dronedarone-induced cytotoxicity.

Newsemia
Related Articles Heterotropic activation of flavonoids on cytochrome P450 3A4: a case example of alleviating dronedarone-induced cytotoxicity. Toxicol Lett. 2019 Nov 19;: Authors: Bai J,...
Pharma / Biotech

Stimulation of 5-HT2C serotonin receptor subtype in the hypothalamic arcuate nuclei (ARC) increases the cytochrome P450 activity in the liver.

Newsemia
Related Articles Stimulation of 5-HT2C serotonin receptor subtype in the hypothalamic arcuate nuclei (ARC) increases the cytochrome P450 activity in the liver. Pharmacol Rep. 2019...
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Cytochrome c oxidase: oxygen consumption, energy conservation and control

Newsemia
Rich, P; (2019) Cytochrome c oxidase: oxygen consumption, energy conservation and control. In: Nixon, P and Ruban, A and Barber, J, (eds.) Oxygen Production And...
Pharma / Biotech

Drug-Drug Interaction Study to Assess the Effect of Cytochrome P450 Inhibition and Induction on the Pharmacokinetics of the Novel Cereblon Modulator Avadomide (CC-122) in Healthy Adult Subjects.

Newsemia
Drug-Drug Interaction Study to Assess the Effect of Cytochrome P450 Inhibition and Induction on the Pharmacokinetics of the Novel Cereblon Modulator Avadomide (CC-122) in Healthy...
Pharma / Biotech

Impacts of Cytochrome P450 2D6*10 Allele and a High-Fat Meal on the Pharmacokinetics of Dapoxetine in Healthy Chinese Men: A Single-Dose, Two-Treatment Study.

Newsemia
Related Articles Impacts of Cytochrome P450 2D6*10 Allele and a High-Fat Meal on the Pharmacokinetics of Dapoxetine in Healthy Chinese Men: A Single-Dose, Two-Treatment Study....
Pharma / Biotech

Microdosed midazolam for the determination of cytochrome P450 3A activity: Development and clinical evaluation of a buccal film.

Newsemia
Related Articles Microdosed midazolam for the determination of cytochrome P450 3A activity: Development and clinical evaluation of a buccal film. Eur J Pharm Sci. 2019...
Pharma / Biotech

Cytochrome P450 enzymes contribute to the metabolism of LSD to nor-LSD and 2-oxo-3-hydroxy-LSD: Implications for clinical LSD use.

Newsemia
Related Articles Cytochrome P450 enzymes contribute to the metabolism of LSD to nor-LSD and 2-oxo-3-hydroxy-LSD: Implications for clinical LSD use. Biochem Pharmacol. 2019 Apr 11;:...
Pharma / Biotech

Inhibitory effects of antihypertensive drugs on human cytochrome P450 2J2 activity: Potent inhibition by azelnidipine and manidipine.

Newsemia
Inhibitory effects of antihypertensive drugs on human cytochrome P450 2J2 activity: Potent inhibition by azelnidipine and manidipine. Chem Biol Interact. 2019 Apr 06;: Authors: Ikemura...
Pharma / Biotech

Effects of sinapic acid on hepatic cytochrome P450 3A2, 2C11, and intestinal P-glycoprotein on the pharmacokinetics of oral carbamazepine in rats: Potential food/herb-drug interaction.

Newsemia
Related Articles Effects of sinapic acid on hepatic cytochrome P450 3A2, 2C11, and intestinal P-glycoprotein on the pharmacokinetics of oral carbamazepine in rats: Potential food/herb-drug...

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