controls

Researchers identify genetic switch that controls conversion of bad to good fat

Fat cells. They are the bane of a dieter's existence, but fat is important. Previous studies showed the subcutaneous white fat cells can transform to brown and beige varieties when...

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Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin

[ad_1] Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin Source link [ad_1]

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Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ<sup>+</sup>CD8αα<sup>+</sup> T cells

by Chieko Ishifune, Shin-ichi Tsukumo, Yoichi Maekawa, Katsuto Hozumi, Doo Hyun Chung, Chihiro Motozono, Sho Yamasaki, Hiroyasu Nakano, Koji Yasutomo Intestinal intraepithelial lymphocytes (IELs) expressing CD8αα on αβ T cells...

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Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery

by Avnish Patel, Abigail J. Perrin, Helen R. Flynn, Claudine Bisson, Chrislaine Withers-Martinez, Moritz Treeck, Christian Flueck, Giuseppe Nicastro, Stephen R. Martin, Andres Ramos, Tim W. Gilberger, Ambrosius P. Snijders,...

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A novel regulatory circuit between p53 and GFI1 controls induction of apoptosis in T cells

The post A novel regulatory circuit between p53 and GFI1 controls induction of apoptosis in T cells appeared first on Biochemistry Blog: Biochemistry Help. Source link

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The Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling Pathways [Research Article]

Delineating the mechanisms that drive hepatic injury and hepatocellular carcinoma (HCC) progression is critical for development of novel treatments for recurrent and advanced HCC but also for the development of...

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Winners, losers, and controls

Innumerable explanations have been put forth for the failures that have occurred in translating promising preclinical and early-phase treatments in ischemic and hemorrhagic stroke. In their work over the last...

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Eph signaling controls mitotic spindle orientation and cell proliferation in neuroepithelial cells

Mitotic spindle orientation must be tightly regulated during development and adult tissue homeostasis. It determines cell-fate specification and tissue architecture during asymmetric and symmetric cell division, respectively. Here, we uncover...

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The Wave complex controls epidermal morphogenesis and proliferation by suppressing Wnt-Sox9 signaling

Development of the skin epidermis requires tight spatiotemporal control over the activity of several signaling pathways; however, the mechanisms that orchestrate these events remain poorly understood. Here, we identify a...

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Heterogeneous drug tissue binding in brain regions of rats, Alzheimer’s patients and controls: impact on translational drug development

Heterogeneous drug tissue binding in brain regions of rats, Alzheimer’s patients and controls: impact on translational drug development Source link

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Trade-Induced Atmospheric Mercury Deposition over China and Implications for Demand-Side Controls

[ad_1] Chen, L; Meng, J; Liang, S; Zhang, H; Zhang, W; Liu, M; Tong, Y; ... Shu, J; + view all Chen, L; Meng, J; Liang, S; Zhang, H; Zhang,...

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A Robust Auxin Response Network Controls Embryo and Suspensor Development through a Basic Helix Loop Helix Transcriptional Module

Land plants reproduce sexually by developing an embryo from a fertilized egg cell. However, embryos can also be formed from other cell types in many plant species. Thus, a key...

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miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity

by Marcin Łyszkiewicz, Samantha J. Winter, Katrin Witzlau, Lisa Föhse, Rebecca Brownlie, Jacek Puchałka, Nikita A. Verheyden, Heike Kunze-Schumacher, Esther Imelmann, Jonas Blume, Solaiman Raha, Takashi Sekiya, Akihiko Yoshimura, Jochen...

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The APETALA2-Like Transcription Factor SUPERNUMERARY BRACT Controls Rice Seed Shattering and Seed Size

The elimination of seed shattering was a crucial event during crop domestication. Improving and fine-tuning the regulation of this process will further enhance grain yield by avoiding seed losses during...

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Study reveals how the microbiota controls activity of immune cells

[ad_1] A host protein called Serum Amyloid A (Saa) is a major factor mediating the effects of the microbiota on the function of immune cells called neutrophils, according to a...

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A Phase 1 Study to Evaluate the Pharmacokinetics and Safety of Cabotegravir in Patients With Hepatic Impairment and Healthy Matched Controls.

[ad_1] Related Articles A Phase 1 Study to Evaluate the Pharmacokinetics and Safety of Cabotegravir in Patients With Hepatic Impairment and Healthy Matched Controls. Clin Pharmacol Drug Dev. 2019 Feb...

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Nathan Sandmaier Becomes Fourth Superior Controls Employee to Attain Licensed Professional Engineer Status

[ad_1] SEABROOK, N.H. (PRWEB) February 26, 2019 Superior Controls, Inc., a leading Life Sciences control system integrator of custom industrial automation and IT solutions with 140 employees on both the...

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Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism

[ad_1] Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism Source link [ad_1]

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P141 A LONG NONCODING RNA TRANSCRIBED FROM THE CD8 LOCUS CONTROLS FUNCTIONAL DIFFERENTIATION OF CD4 T CELLS IN THE INTESTINE

[ad_1] CD4 T cells adapt their immune function to the local tissue environment by differentiating into various functional subsets. At steady state, regulatory CD4 T cells (Treg) and interleukin (IL)-17-producing...

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Superior Controls Expands Executive Team with the Hire of Experienced Business Development Manager Ron Case to Serve the New England Region

[ad_1] SEABROOK, N.H. (PRWEB) February 20, 2019 Superior Controls, Inc. , a leading life sciences control system integrator of custom industrial automation and IT solutions with 140 employees on both...

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