Conjugate – Newsemia

Camidanlumab tesirine, an antibody-drug conjugate, in relapsed/refractory CD25-positive acute myeloid leukemia or acute lymphoblastic leukemia: A phase I study.

NewsemiaJune 11, 2020

by NewsemiaJune 11, 202008

Related Articles Camidanlumab tesirine, an antibody-drug conjugate, in relapsed/refractory CD25-positive acute myeloid leukemia or acute lymphoblastic leukemia: A phase I study. Leuk Res. 2020 Jun...

Pediatrics

Pneumococcal Conjugate Vaccine Breakthrough Infections: 2001-2016

NewsemiaMarch 11, 2020

by NewsemiaMarch 11, 2020035

BACKGROUND: Most countries use 3-dose pneumococcal conjugate vaccine (PCV) schedules; a 4-dose (3 primary and 1 booster) schedule is licensed for US infants. We evaluated the...

Gastroenterology

Anti-glypican-1 antibody–drug conjugate is a potential therapy against pancreatic cancer

NewsemiaMarch 10, 2020

by NewsemiaMarch 10, 2020013

Anti-glypican-1 antibody–drug conjugate is a potential therapy against pancreatic cancer Source link...

Latest News

New antibody-drug conjugate shows promising activity in salivary gland tumors

NewsemiaJanuary 7, 2020

by NewsemiaJanuary 7, 2020038

The antibody-drug conjugate ado-trastuzumab emtansine (T-DM1) has promising activity in HER2 amplified salivary gland tumors, according to data published in the Annals of Oncology. Source...

Pediatrics

Asthma and Invasive Pneumococcal Disease in the Age of Pneumococcal Conjugate Vaccines

NewsemiaJanuary 3, 2020

by NewsemiaJanuary 3, 2020034

Asthma and Invasive Pneumococcal Disease in the Age of Pneumococcal Conjugate Vaccines Source link...

Biology

Conjugate eye movements guide jumping locomotion in an avian species [RESEARCH ARTICLE]

NewsemiaNovember 2, 2019

by NewsemiaNovember 2, 201902

Jessica L. Yorzinski Many animals rely on vision to successfully locomote through their environments. However, our understanding of the interaction between vision and locomotion is...

Latest News

Contributed Discussion of "A Bayesian Conjugate Gradient Method"

NewsemiaSeptember 16, 2019

by NewsemiaSeptember 16, 201903

Briol, F-X; Francisco, ADDLO; Hristov, PO; (2019) Contributed Discussion of “A Bayesian Conjugate Gradient Method”. Bayesian Analysis 10.1214/19-BA1145 . (In press). Source link...

Pharma / Biotech

Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma.

NewsemiaAugust 8, 2019

by NewsemiaAugust 8, 201906

Related Articles Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma. Invest...

Latest News

Novel anti-VEGF antibody biopolymer conjugate safe, effective in early phase 1b results

NewsemiaJuly 28, 2019

by NewsemiaJuly 28, 201903

CHICAGO — Multiple intravitreal administrations of KSI-301, a novel anti-VEGF antibody biopolymer conjugate, improved best corrected visual acuity and retinal anatomy in patients with wet...

Pediatrics

Predictors of uptake of newly introduced vaccines in Malawi – monovalent human rotavirus and pneumococcal conjugate vaccines: Evidence from the 2015–16 Malawi demographic and health survey

NewsemiaJune 14, 2019

by NewsemiaJune 14, 201909

Abstract Objectives The purpose of this study was to examine the uptake and predictors of monovalent human rotavirus and pneumococcal conjugate vaccines among children of...

Latest News

Pfizer Announces Presentation of Data from a Phase 2 Study of its 20-Valent Pneumococcal Conjugate Vaccine Candidate Being Investigated for the Prevention of Invasive Disease and Pneumonia in Adults Aged 18 Years and Older

NewsemiaApril 13, 2019

by NewsemiaApril 13, 201904

NEW YORK–(BUSINESS WIRE)–Pfizer Inc. (NYSE: PFE) announced today the presentation of data from a Phase 2 study of its 20-valent pneumococcal conjugate vaccine (20vPnC) candidate,...

Pharma / Biotech

A UHPLC-MS/MS method coupled with simple and efficient alkaline hydrolysis for free and total determination of conjugate nanomedicine: Pharmacokinetic and biodistribution study of poly (l-glutamic acid)-graft-methoxy poly (ethylene glycol)/combretastatin A4.

NewsemiaMarch 18, 2019

by NewsemiaMarch 18, 201903

Related Articles A UHPLC-MS/MS method coupled with simple and efficient alkaline hydrolysis for free and total determination of conjugate nanomedicine: Pharmacokinetic and biodistribution study of...

Pediatrics

Antibody-Drug Conjugate, from a Growing Class of Highly Potent Anticancer Drugs, Shows Efficacy against Cell Surface Protein in Neuroblastoma

NewsemiaMarch 13, 2019

by NewsemiaMarch 13, 201902

Physician-scientists in the Cancer Center at Children’s Hospital of Philadelphia have developed a preclinical, potent therapy attached to an antibody that targets a surface protein...

Latest News

Researchers unveil progress and challenges in introducing typhoid conjugate vaccine in Africa/Asia

NewsemiaMarch 10, 2019

by NewsemiaMarch 10, 201906

Each year there are nearly 11 million cases of typhoid, a disease that is spread through contaminated food, drink and water. Researchers at the University...

Cardiology

Breakthrough Therapy Granted to 15-Valent Pneumococcal Conjugate Vaccine

NewsemiaJanuary 31, 2019

by NewsemiaJanuary 31, 201906

Phase 3 studies investigating safety, tolerability, and immunogenicity in both adults and children are currently underway. Source link...

Latest News

Safety and immunogenicity of the Cuban heptavalent pneumococcal conjugate vaccine in healthy infants. Results from a double-blind randomized control trial Phase I

NewsemiaJanuary 28, 2019

by NewsemiaJanuary 28, 201905

Dotres Martinez, CP; Linares-Perez, N; Toledo-Romani, ME; Ricardo Delgado, Y; Puga Gomez, R; Paredes Moreno, B; Rodriguez-Noda, LM; … Alvarez, A; + view all Dotres...

Latest News

Immunogenicity and safety of a booster dose of the 13-valent pneumococcal conjugate vaccine in children primed with the 10-valent or 13-valent pneumococcal conjugate vaccine in the Czech Republic and Slovakia

NewsemiaJanuary 25, 2019

by NewsemiaJanuary 25, 2019014

Urbancikova, I; Prymula, R; Goldblatt, D; Roalfe, L; Prymulova, K; Kosina, P; (2017) Immunogenicity and safety of a booster dose of the 13-valent pneumococcal conjugate...

Pediatrics

Change in Pneumococcus Serotypes but not Mortality or Morbidity in Pre- and Post-13-Valent Polysaccharide Conjugate Vaccine Era: Epidemiology in a Pediatric Intensive Care Unit over 10 Years

NewsemiaOctober 16, 2018

by NewsemiaOctober 16, 201803

ABSTRACT Aim Pneumococcus is a common commensal and an important pathogen among children for which immunization is available. Some serotypes occasionally cause severe pneumococcal disease...

Pharma / Biotech

Self-assembling lisofylline-fatty acid conjugate for effective treatment of diabetes mellitus.

NewsemiaOctober 11, 2018

by NewsemiaOctober 11, 201803

Related Articles Self-assembling lisofylline-fatty acid conjugate for effective treatment of diabetes mellitus. Nanomedicine. 2018 Oct 06;: Authors: Italiya KS, Mazumdar S, Sharma S, Chitkara D,...

Pharma / Biotech

First-in-Human Phase I, Dose-Escalation and -Expansion Study of Telisotuzumab Vedotin, an Antibody-Drug Conjugate Targeting c-Met, in Patients With Advanced Solid Tumors.

NewsemiaOctober 6, 2018

by NewsemiaOctober 6, 201803

Related Articles First-in-Human Phase I, Dose-Escalation and -Expansion Study of Telisotuzumab Vedotin, an Antibody-Drug Conjugate Targeting c-Met, in Patients With Advanced Solid Tumors. J Clin...

Newsemia

Tag: Conjugate

Camidanlumab tesirine, an antibody-drug conjugate, in relapsed/refractory CD25-positive acute myeloid leukemia or acute lymphoblastic leukemia: A phase I study.

Pneumococcal Conjugate Vaccine Breakthrough Infections: 2001-2016

Anti-glypican-1 antibody–drug conjugate is a potential therapy against pancreatic cancer

New antibody-drug conjugate shows promising activity in salivary gland tumors

Asthma and Invasive Pneumococcal Disease in the Age of Pneumococcal Conjugate Vaccines

Conjugate eye movements guide jumping locomotion in an avian species [RESEARCH ARTICLE]

Contributed Discussion of "A Bayesian Conjugate Gradient Method"

Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma.

Novel anti-VEGF antibody biopolymer conjugate safe, effective in early phase 1b results

Predictors of uptake of newly introduced vaccines in Malawi – monovalent human rotavirus and pneumococcal conjugate vaccines: Evidence from the 2015–16 Malawi demographic and health survey

Pfizer Announces Presentation of Data from a Phase 2 Study of its 20-Valent Pneumococcal Conjugate Vaccine Candidate Being Investigated for the Prevention of Invasive Disease and Pneumonia in Adults Aged 18 Years and Older

A UHPLC-MS/MS method coupled with simple and efficient alkaline hydrolysis for free and total determination of conjugate nanomedicine: Pharmacokinetic and biodistribution study of poly (l-glutamic acid)-graft-methoxy poly (ethylene glycol)/combretastatin A4.

Antibody-Drug Conjugate, from a Growing Class of Highly Potent Anticancer Drugs, Shows Efficacy against Cell Surface Protein in Neuroblastoma

Researchers unveil progress and challenges in introducing typhoid conjugate vaccine in Africa/Asia

Breakthrough Therapy Granted to 15-Valent Pneumococcal Conjugate Vaccine

Safety and immunogenicity of the Cuban heptavalent pneumococcal conjugate vaccine in healthy infants. Results from a double-blind randomized control trial Phase I

Immunogenicity and safety of a booster dose of the 13-valent pneumococcal conjugate vaccine in children primed with the 10-valent or 13-valent pneumococcal conjugate vaccine in the Czech Republic and Slovakia

Change in Pneumococcus Serotypes but not Mortality or Morbidity in Pre- and Post-13-Valent Polysaccharide Conjugate Vaccine Era: Epidemiology in a Pediatric Intensive Care Unit over 10 Years

Self-assembling lisofylline-fatty acid conjugate for effective treatment of diabetes mellitus.

First-in-Human Phase I, Dose-Escalation and -Expansion Study of Telisotuzumab Vedotin, an Antibody-Drug Conjugate Targeting c-Met, in Patients With Advanced Solid Tumors.

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