Tag : Computational Biology

AI/ML

AFP-LSE: Antifreeze Proteins Prediction Using Latent Space Encoding of Composition of k-Spaced Amino Acid Pairs.

Newsemia
Related Articles AFP-LSE: Antifreeze Proteins Prediction Using Latent Space Encoding of Composition of k-Spaced Amino Acid Pairs. Sci Rep. 2020 04 28;10(1):7197 Authors: Usman M,...
AI/ML

Machine Learning and Bioinformatics Models to Identify Pathways that Mediate Influences of Welding Fumes on Cancer Progression.

Newsemia
Related Articles Machine Learning and Bioinformatics Models to Identify Pathways that Mediate Influences of Welding Fumes on Cancer Progression. Sci Rep. 2020 02 17;10(1):2795 Authors:...
AI/ML

Identification of genes and pathways associated with subchondral bone in osteoarthritis via bioinformatic analysis.

Newsemia
Related Articles Identification of genes and pathways associated with subchondral bone in osteoarthritis via bioinformatic analysis. Medicine (Baltimore). 2020 Sep 11;99(37):e22142 Authors: Yang Z, Ni...
AI/ML

Circular RNA profiling of neutrophil transcriptome provides insights into asymptomatic Moyamoya disease.

Newsemia
Related Articles Circular RNA profiling of neutrophil transcriptome provides insights into asymptomatic Moyamoya disease. Brain Res. 2019 09 15;1719:104-112 Authors: Ma Q, Li L, Yu...
AI/ML

A Novel Amino Acid Properties Selection Method for Protein Fold Classification.

Newsemia
Related Articles A Novel Amino Acid Properties Selection Method for Protein Fold Classification. Protein Pept Lett. 2020;27(4):287-294 Authors: Zhang L, Kong L Abstract BACKGROUND: Amino...
AI/ML

MELK is Upregulated in Advanced Clear Cell Renal Cell Carcinoma and Promotes Disease Progression by Phosphorylating PRAS40.

Newsemia
Related Articles MELK is Upregulated in Advanced Clear Cell Renal Cell Carcinoma and Promotes Disease Progression by Phosphorylating PRAS40. Cell Transplant. 2019 Dec;28(1_suppl):37S-50S Authors: Zhang...
AI/ML

Creating reproducible pharmacogenomic analysis pipelines.

Newsemia
Related Articles Creating reproducible pharmacogenomic analysis pipelines. Sci Data. 2019 09 03;6(1):166 Authors: Mammoliti A, Smirnov P, Safikhani Z, Ba-Alawi W, Haibe-Kains B Abstract The...
AI/ML

Identification of potential key genes associated with osteosarcoma based on integrated bioinformatics analyses.

Newsemia
Related Articles Identification of potential key genes associated with osteosarcoma based on integrated bioinformatics analyses. J Cell Biochem. 2019 08;120(8):13554-13561 Authors: Hu G, Cheng Z,...
AI/ML

Artificial intelligence in drug combination therapy.

Newsemia
Related Articles Artificial intelligence in drug combination therapy. Brief Bioinform. 2019 07 19;20(4):1434-1448 Authors: Tsigelny IF Abstract Currently, the development of medicines for complex diseases...
Pediatrics

New Computational Model by CHOP Researchers Identifies Noncoding Mutations Across Five Pediatric Cancers

Newsemia
Researchers at Children’s Hospital of Philadelphia (CHOP) have developed a new computational algorithm that has, for the first time, identified a spectrum of mutations in...
Pediatrics

New Computational Tools Identify Alternative Splicing Changes in Aggressive Cancers

Newsemia
A multi-institutional group of researchers led by Children’s Hospital of Philadelphia (CHOP) has linked a strong cancer driver gene to changes in proteins that regulate...
Pediatrics

Scientists Identify Gene as a Master Regulator in Schizophrenia

Newsemia
Using computational tools to investigate gene transcription networks in large collections of brain tissues, a scientific team has identified a gene that acts as a...
Biology

Challenges and recommendations to improve the installability and archival stability of omics computational tools

Newsemia
by Serghei Mangul, Thiago Mosqueiro, Richard J. Abdill, Dat Duong, Keith Mitchell, Varuni Sarwal, Brian Hill, Jaqueline Brito, Russell Jared Littman, Benjamin Statz, Angela Ka-Mei...
Pediatrics

New Computational Tool Harnesses Big Data and Deep Learning to Illuminate 'Dark Matter' of the Transciptome

Newsemia
A research team at Children’s Hospital of Philadelphia has developed an innovative computational tool offering researchers an efficient method for detecting the different ways RNA...
Pediatrics

Scientific Leader Launches New Center for Computational and Genomic Medicine

Newsemia
As computational biologist Yi Xing, PhD, launches the Center for Computational and Genomic Medicine at Children’s Hospital of Philadelphia, he draws on his “bilingual” strengths....

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